Design of an optical fiber sensor for detecting in situ the composition of pharmaceuticals in blood

1996 ◽  
Author(s):  
Yueqing Gu ◽  
Zhiyu Qian ◽  
Baoqi Tao ◽  
Shengkai Huang
Keyword(s):  
Optical Fiber ◽  
Optical Fiber Sensor ◽  
Fiber Sensor

scholarly journals Fabrication of a Bare Optical Fiber-Based Biosensor

Micromachines ◽  
2019 ◽  
Vol 10 (8) ◽  
pp. 522
Author(s):  
Yu-Jun Zhang ◽  
Jin-Cherng Hsu ◽  
Jia-Huey Tsao ◽  
Yung-Shin Sun
Keyword(s):  
Refractive Index ◽  
Optical Fiber ◽  
Gold Film ◽  
Optical Fiber Sensor ◽  
Binding Kinetics ◽  
Fiber Sensor ◽  
Sensor Surface ◽  
Material Interface ◽  
Kinetics Of

A bare optical fiber-based biosensor is proposed for measuring the refractive index of different liquids and the binding kinetics of biomolecules to the sensor surface. This optical fiber sensor is based on the Kretschmann’s configuration to attain total internal reflection (TIR) for surface plasmon resonance (SPR) excitation. One end of the bare optical fiber is coated with a gold film. By guiding the light source from the other end into the optical fiber, the light is reflected from the gold-deposited end and the surface evanescent wave is excited in the gold film-transparent material interface. Methanol and ethanol solutions with different refractive indices are used for measuring the corresponding changes in the peak values of the spectra and calculating the corresponding sensitivities. These values are experimentally determined to be in the order of 10−4~10−5 refractive index unit (RIU). Binding of proteins onto the sensor surface is also monitored in real time to obtain the binding kinetics. We believe that, in the future, this optical fiber sensor can serve as a useful biosensor for in situ measurement of allergens, antibody–antigen interactions, and even circulating tumor cells in the blood.

scholarly journals Polydopamine-Assisted Fabrication of Stable Silver Nanoparticles on Optical Fiber for Enhanced Plasmonic Sensing

2019 ◽  
Vol 10 (2) ◽  
pp. 97-104 ◽  
Author(s):  
Yiwen Tang ◽  
Hui Yuan ◽  
Jiangping Chen ◽  
Qiguo Xing ◽  
Rongxin Su ◽  
...  
Keyword(s):  
Optical Fiber ◽  
Localized Surface Plasmon Resonance ◽  
Optical Fiber Sensor ◽  
Redox Activity ◽  
Fiber Sensor ◽  
Localized Surface Plasmon ◽  
Future Application ◽  
Ag Nps ◽  
Plasmonic Sensing

Abstract We present a facile and effective method for fabrication of the localized surface plasmon resonance (LSPR) optical fiber sensor assisted by two polydopamine (PDA) layers with enhanced plasmonic sensing performance. The first PDA layer was self-polymerized onto the bare optical fiber to provide the catechol groups for the reduction from Ag+ to Ago through chelating and redox activity. As the reduction of Ag+ proceeds, Ag nanoparticles (NPs) were grown in-situ on the PDA layer with uniform distribution. The second PDA layer was applied to prevent Ag NPs from oxidating and achieve an improvement of LSPR signal. The PDA/Ag/PDA-based optical fiber sensor has an enhanced LSPR sensitivity of 961 nm/RIU and excellent oxidation resistance. The stable PDA/Ag/PDA-based LSPR sensor with high optical performance is very promising for future application in optical sensing field.

scholarly journals Dynamic Monitoring of Multi-Concentrated Silica Nanoparticles Colloidal Environment with Optical Fiber Sensor

Proceedings ◽  
2019 ◽  
Vol 42 (1) ◽  
pp. 6
Author(s):  
Marco César Prado Soares ◽  
Matheus Santos Rodrigues ◽  
Egont Alexandre Schenkel ◽  
Willian Hideak Arita Silva ◽  
Gabriel Perli ◽  
...  
Keyword(s):  
Optical Fiber ◽  
Silica Nanoparticles ◽  
Optical Fiber Sensor ◽  
Dynamic Monitoring ◽  
Fiber Sensor ◽  
Concentration Gradients ◽  
Elastic Light Scattering ◽  
Reflected Light ◽  
Non Destructive

Colloids are metastable suspensions of particles dispersed in a base fluid, with high scientific and industrial importance, but the monitoring of these systems still demands expensive and large instrumentation. In this research, the measurement of concentration gradients in colloidal silica samples using an optical fiber sensor is reported. Silica nanoparticles (measuring 189 nm) were sedimented in test tubes for creating environments with different concentrations. The fiber probe was immersed in the assessed liquid, resulting in an increase in the dispersion of the reflected light intensity, which is caused by the particles Brownian motion. Therefore, the quasi-elastic light scattering phenomenon related to the diffusivity can be analyzed, providing information about the concentration gradients of the nanosystem with a straightforward, in situ, and non-destructive approach.

scholarly journals Enhanced fabrication process for in situ triboluminescent optical fiber sensor for multifunctional composites

Measurement ◽  
2018 ◽  
Vol 121 ◽  
pp. 240-248 ◽  
Author(s):  
Md Abu Shohag ◽  
Yourri-Samuel Dessureault ◽  
Kunal Joshi ◽  
Taniwa Ndebele ◽  
David Olawale ◽  
...  
Keyword(s):  
Optical Fiber ◽  
Optical Fiber Sensor ◽  
Fabrication Process ◽  
Fiber Sensor ◽  
Multifunctional Composites
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