In-situ strain monitoring in composites using an embedded extrinsic Fabry-Perot interferometric sensor and a CCD detection system

Author(s):  
Tonguy Liu ◽  
F. Ai-Khodairi ◽  
M. Q. Wu ◽  
M. Irle ◽  
Gerard F. Fernando
Coatings ◽  
2020 ◽  
Vol 10 (12) ◽  
pp. 1174
Author(s):  
Sijia Li ◽  
Yulong Li ◽  
Xubo Liu ◽  
Xuewen Li ◽  
Tao Ding ◽  
...  

In this study, in-situ electroplating method was used to fabricate a metal joint fixed extrinsic Fabry-Perot interferometric (EFPI) sensor. Specifically, optical fibers were firstly chemical plated with a very thin conductive nickel layer and then electroplated with nickel coating. After that, in-situ electroplating method was used to fix the metallized optical fibers and the capillary steel tube, the reflection spectra changes of the EFPI sensors during the in-situ electroplating process were recorded in real time, and the temperature sensing characteristics of the EFPI sensors were studied assisted by the temperature sensing system. Results show that: (i) optical fibers are well protected by the nickel layer; (ii) the reflection spectra of the EFPI sensors are clear and complete in the whole in-situ electroplating process, it is feasible to fabricate a EFPI sensor with the in-situ electroplating method; (iii) with the increases of temperature, the peak numbers of the reflection spectra of the EFPI sensors increase gradually; (iv) the EFPI sensors with different cavity length based on the in-situ electroplating method show excellent sensing characteristics, the temperature sensitivities reach up to about 700, 600, and 400 pm/°C from room temperature to 400 °C, respectively.


Author(s):  
G. W. Hacker ◽  
I. Zehbe ◽  
J. Hainfeld ◽  
A.-H. Graf ◽  
C. Hauser-Kronberger ◽  
...  

In situ hybridization (ISH) with biotin-labeled probes is increasingly used in histology, histopathology and molecular biology, to detect genetic nucleic acid sequences of interest, such as viruses, genetic alterations and peptide-/protein-encoding messenger RNA (mRNA). In situ polymerase chain reaction (PCR) (PCR in situ hybridization = PISH) and the new in situ self-sustained sequence replication-based amplification (3SR) method even allow the detection of single copies of DNA or RNA in cytological and histological material. However, there is a number of considerable problems with the in situ PCR methods available today: False positives due to mis-priming of DNA breakdown products contained in several types of cells causing non-specific incorporation of label in direct methods, and re-diffusion artefacts of amplicons into previously negative cells have been observed. To avoid these problems, super-sensitive ISH procedures can be used, and it is well known that the sensitivity and outcome of these methods partially depend on the detection system used.


Author(s):  
Shadi Azam ◽  
Mikael Eriksson ◽  
Arvid Sjölander ◽  
Marike Gabrielson ◽  
Roxanna Hellgren ◽  
...  

Abstract Background Mammographic microcalcifications are considered early signs of breast cancer (BC). We examined the association between microcalcification clusters and the risk of overall and subtype-specific BC. Furthermore, we studied how mammographic density (MD) influences the association between microcalcification clusters and BC risk. Methods We used a prospective cohort (n = 53,273) of Swedish women with comprehensive information on BC risk factors and mammograms. The total number of microcalcification clusters and MD were measured using a computer-aided detection system and the STRATUS method, respectively. Cox regressions and logistic regressions were used to analyse the data. Results Overall, 676 women were diagnosed with BC. Women with ≥3 microcalcification clusters had a hazard ratio [HR] of 2.17 (95% confidence interval [CI] = 1.57–3.01) compared to women with no clusters. The estimated risk was more pronounced in premenopausal women (HR = 2.93; 95% CI = 1.67–5.16). For postmenopausal women, microcalcification clusters and MD had a similar influence on BC risk. No interaction was observed between microcalcification clusters and MD. Microcalcification clusters were significantly associated with in situ breast cancer (odds ratio: 2.03; 95% CI = 1.13–3.63). Conclusions Microcalcification clusters are an independent risk factor for BC, with a higher estimated risk in premenopausal women. In postmenopausal women, microcalcification clusters have a similar association with BC as baseline MD.


Sensors ◽  
2018 ◽  
Vol 18 (8) ◽  
pp. 2712 ◽  
Author(s):  
Jihaeng Yi

This paper presents a monolithic sapphire pressure sensor that is constructed from two commercially available sapphire wafers through a combination of reactive-ion etching and wafer bonding. A Fabry–Perot (FP) cavity is sealed fully between the adhesive-free bonded sapphire wafers and thus acts as a pressure transducer. A combination of standard silica fiber, bonded sapphire wafers and free-space optics is proposed to couple the optical signal to the FP cavity of the sensor. The pressure in the FP cavity is measured by applying both white-light interferometry and diaphragm deflection theory over a range of 0.03 to 3.45 MPa at room temperature. With an all-sapphire configuration, the adhesive-free bonded sapphire sensor is expected to be suitable for in-situ pressure measurements in extreme harsh environments.


2019 ◽  
Vol 21 ◽  
pp. 29
Author(s):  
E. G. Androulakaki ◽  
C. Tsabaris ◽  
M. Kokkoris ◽  
G. Eleftheriou ◽  
D. L. Patiris ◽  
...  

The in-situ gamma-ray spectrometry is a well suited method for seabed mapping applications, since it provides rapid results in a cost effective manner. Moreover, the in-situ method is preferable to the commonly applied laboratory measurements, due to its beneficial characteristics. Therefore, the development of in-situ systems for seabed measurements continuously grows. However, an efficiency calibration of the detection system is necessary for obtaining quantitative results in the full spectral range. In the present work, an approach for calculating the full-energy peak efficiency of an underwater insitu spectrometer for measure- ments on the seabed is presented. The experimental work was performed at the coastal site of Vasilikos (Cyprus). The experimental full-energy peak efficiency of the in-situ was determined in the energy range 1400–2600 keV, by combining the in-situ and laboratory reference measurements. The experimental effi- ciency results were theoretically reproduced by means of Monte Carlo (MC) simulations, using the MCNP5 code.


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