scholarly journals Non-contact trapping and stretching of biological cells using dual-beam optical stretcher on microfluidic platform

2019 ◽  
Author(s):  
Aotuo Dong ◽  
Balaadithya Uppalapati ◽  
Md. Shariful Islam ◽  
Brandon Gibbs ◽  
Ganesan Kamatchi ◽  
...  
Keyword(s):  
Biological Cells ◽  
Microfluidic Platform ◽  
Dual Beam ◽  
Optical Stretcher

Optical Stretcher of Biological Cells Using Sub-Nanometer Optical Tweezers Generated by an Add/Drop Microring Resonator System

2014 ◽  
Vol 6 (2) ◽  
pp. 111-117 ◽  
Author(s):  
I. S. Amiri ◽  
B. Barati ◽  
P. Sanati ◽  
A. Hosseinnia ◽  
H. R. Mansouri Khosravi ◽  
...  
Keyword(s):  
Optical Tweezers ◽  
Microring Resonator ◽  
Biological Cells ◽  
Optical Stretcher ◽  
Resonator System

scholarly journals Calculation of spherical red blood cell deformation in a dual-beam optical stretcher

2007 ◽  
Vol 15 (24) ◽  
pp. 16029 ◽  
Author(s):  
Paul B. Bareil ◽  
Yunlong Sheng ◽  
Yin-Quan Chen ◽  
Arthur Chiou
Keyword(s):  
Blood Cell ◽  
Red Blood Cell ◽  
Cell Deformation ◽  
Dual Beam ◽  
Optical Stretcher

The optical stretcher as a tool for single-particle X-ray imaging and diffraction

2018 ◽  
Vol 25 (4) ◽  
pp. 1196-1205 ◽  
Author(s):  
Jan-David Nicolas ◽  
Johannes Hagemann ◽  
Michael Sprung ◽  
Tim Salditt
Keyword(s):  
Elastic Properties ◽  
Optical Tweezers ◽  
Free Electron ◽  
High Throughput Screening ◽  
Structural Parameters ◽  
Biological Cells ◽  
X Ray Diffraction ◽  
X Ray ◽  
Single Beam ◽  
Optical Stretcher

For almost half a century, optical tweezers have successfully been used to micromanipulate micrometre and sub-micrometre-sized particles. However, in recent years it has been shown experimentally that, compared with single-beam traps, the use of two opposing and divergent laser beams can be more suitable in studying the elastic properties of biological cells and vesicles. Such a configuration is termed an optical stretcher due to its capability of applying high deforming forces on biological objects such as cells. In this article the experimental capabilities of an optical stretcher as a potential sample delivery system for X-ray diffraction and imaging studies at synchrotrons and X-ray free-electron laser (FEL) facilites are demonstrated. To highlight the potential of the optical stretcher its micromanipulation capabilities have been used to image polymer beads and label biological cells. Even in a non-optimized configuration based on a commercially available optical stretcher system, X-ray holograms could be recorded from different views on a biological cell and the three-dimensional phase of the cell could be reconstructed. The capability of the setup to deform cells at higher laser intensities in combination with, for example, X-ray diffraction studies could furthermore lead to interesting studies that couple structural parameters to elastic properties. By means of high-throughput screening, the optical stretcher could become a useful tool in X-ray studies employing synchrotron radiation, and, at a later stage, femtosecond X-ray pulses delivered by X-ray free-electron lasers.

A microfluidic platform enabling real-time control of dynamic biochemical stimuli to biological cells

2020 ◽  
Vol 30 (9) ◽  
pp. 095011
Author(s):  
Chun-Dong Xue ◽  
Yong-Jiang Li ◽  
Jing-Tong Na ◽  
Yan-Xia Wang ◽  
Hong-Jian Yu ◽  
...  
Keyword(s):  
Real Time ◽  
Biological Cells ◽  
Real Time Control ◽  
Microfluidic Platform ◽  
Time Control

Dual-beam laser micromanipulation for sorting biological cells and its device application

2002 ◽  
Author(s):  
Yoichiroh Hosokawa ◽  
Hiroshi M. Masuhara ◽  
Yoshitaka Matsumoto ◽  
Setsuya Sato
Keyword(s):  
Biological Cells ◽  
Device Application ◽  
Beam Laser ◽  
Dual Beam ◽  
Laser Micromanipulation
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