scholarly journals Fully resolved simulation and ultrasound flow studies in stented carotid aneurysm model

2019 ◽  
Author(s):  
Julia Mikhal ◽  
Astrid M. Hoving ◽  
Gabriela M. Ong ◽  
Cornelis H. Slump
Keyword(s):  
Fully Resolved Simulation ◽  
Aneurysm Model

Intracranial Vessel Wall MRI in a Rabbit Elastase Aneurysm Model

2019 ◽  
Author(s):  
James Ho ◽  
Nakisa Sadeghi ◽  
Ilana Galex ◽  
Nathan Davis ◽  
Sofia Cabello ◽  
...  
Keyword(s):  
Vessel Wall ◽  
Intracranial Vessel ◽  
Aneurysm Model

Arterial aneurysm model using laser energy

1987 ◽  
Author(s):  
Joseph LoCicero III ◽  
Renee S. Hartz M.D. ◽  
Walter J. McCarthy M.D. ◽  
Shou-Ren Shih
Keyword(s):  
Laser Energy ◽  
Arterial Aneurysm ◽  
Aneurysm Model

A Hybrid Coil/Polymer Device for Occlusion of Cerebral Aneurysms

2009 ◽  
Vol 3 (4) ◽  
Author(s):  
Fangmin Xu ◽  
Kevin Hart ◽  
Claire E. Flanagan ◽  
John C. Nacker ◽  
Roham Moftakhar ◽  
...  
Keyword(s):  
Cerebral Aneurysms ◽  
In Vitro Models ◽  
In Vivo Studies ◽  
Polymer Shell ◽  
Device Implantation ◽  
Occlusion Device ◽  
Aneurysm Occlusion ◽  
Aneurysm Model

The treatment of cerebral aneurysms is frequently accomplished via endovascular delivery of metal coils in order to occlude the aneurysm and prevent rupture. This procedure involves imprecise packing of large lengths of wire into the aneurysm and often results in high rates of aneurysm recanalization. Over time, this incomplete aneurysm occlusion can lead to aneurysm enlargement, which may have fatal consequences. This report describes the fabrication and preliminary testing of a novel aneurysm occlusion device composed of a single metal coil surrounded by a biocompatible polymer shell. These coil-in-shell devices were tested under flow conditions in synthetic in vitro models of saccular aneurysms and deployed in vivo in a short-term porcine aneurysm model to study occlusion efficacy. A single nickel titanium shape memory wire was used to deploy a biocompatible, elastic polymeric shell, leading to aneurysmal sac filling in both in vitro and in vivo aneurysm models. The deployment of this coil-in-shell device in synthetic aneurysm models in vitro resulted in varying degrees of aneurysm occlusion, with less than 2% of trials resulting in significant leakage of fluid into the aneurysm. Meanwhile, in vivo coil-in-shell device implantation in a porcine aneurysm model provided proof-of-concept for successful occlusion, as both aneurysms were completely occluded by the devices. Both in vitro and in vivo studies demonstrated that this coil-in-shell device may be attractive as an alternative to traditional coil embolization methods in some cases, allowing for a more precise and controlled aneurysm occlusion.

Simplified experimental cerebral aneurysm model in rats: Comprehensive evaluation of induced aneurysms and arterial changes in the circle of Willis

2009 ◽  
Vol 1300 ◽  
pp. 159-168 ◽  
Author(s):  
Hany Eldawoody ◽  
Hiroaki Shimizu ◽  
Naoto Kimura ◽  
Atsushi Saito ◽  
Toshio Nakayama ◽  
...  
Keyword(s):  
Cerebral Aneurysm ◽  
Comprehensive Evaluation ◽  
Circle Of Willis ◽  
Aneurysm Model

A novel intracranial exchange guidewire improves the navigation of various endovascular devices: An in vitro study of challenging situations

2021 ◽  
pp. 159101992110573
Author(s):  
Naoki Kaneko ◽  
Ariel Takayanagi ◽  
Hamidreza Saber ◽  
Lea Guo ◽  
Satoshi Tateshima
Keyword(s):  
Giant Aneurysm ◽  
In Vitro Study ◽  
Target Vessel ◽  
Success Rates ◽  
Intracranial Stenting ◽  
Aneurysm Neck ◽  
Significant Difference ◽  
Aneurysm Model ◽  
Endovascular Devices

Objective Neuroendovascular procedures rely on successful navigation and stable access to the target vessel. The Stabilizer is a 300 cm long exchange wire with a 0.014 diameter and a soft, flexible stent at the distal end designed to assist with navigation and device delivery. This study aims to assess the efficacy of the Stabilizer for navigation in a variety of challenging environments. Methods The efficacy of the Stabilizer was evaluated using three challenging vascular models: a giant aneurysm model, a severe tortuosity model, and an M1 stenosis model. The Stabilizer was compared with a conventional wire during navigation in each model. Results In the giant aneurysm model, there was no significant difference of success during straightening of a looped wire and significantly higher success rates when advancing an intermediate catheter with the Stabilizer beyond the aneurysm neck compared to a conventional guidewire. The Stabilizer also significantly increased success rates when advancing an intermediate catheter through a model with severe tortuosity compared to a conventional guidewire, as well as exchange maneuver for intracranial stenting in a stenosis model compared to an exchange wire. Conclusions In our experimental model, the Stabilizer significantly improved navigation and device delivery in a variety of challenging settings compared to conventional wires.

Geometric Study of Various Chimney Graft Configurations in an In Vitro Juxtarenal Aneurysm Model

2013 ◽  
Vol 20 (2) ◽  
pp. 184-190 ◽  
Author(s):  
Jorg L. de Bruin ◽  
Kak K. Yeung ◽  
Wouter W. Niepoth ◽  
Rutger J. Lely ◽  
Qingfeng Cheung ◽  
...  
Keyword(s):  
Juxtarenal Aneurysm ◽  
Chimney Graft ◽  
Aneurysm Model ◽  
Geometric Study

scholarly journals A New Canine Carotid Artery Bifurcation Aneurysm Model for the Evaluation of Neurovascular Devices

2009 ◽  
Vol 31 (5) ◽  
pp. 967-971 ◽  
Author(s):  
O. Naggara ◽  
T.E. Darsaut ◽  
I. Salazkin ◽  
G. Soulez ◽  
F. Guilbert ◽  
...  
Keyword(s):  
Carotid Artery ◽  
Carotid Artery Bifurcation ◽  
Bifurcation Aneurysm ◽  
Aneurysm Model
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