Two-tier classifier for identifying small objects in histological tissue classification: experiments with colon cancer tissue mapping

2019 ◽  
Author(s):  
Chen-Yu Sun ◽  
Weiguo Liu ◽  
Scott Doyle
Keyword(s):  
Colon Cancer ◽  
Cancer Tissue ◽  
Tissue Classification ◽  
Colon Cancer Tissue ◽  
Tissue Mapping

scholarly journals Research for Expression and Prognostic Value of GABRD in Colon Cancer and Coexpressed Gene Network Construction Based on Data Mining

2021 ◽  
Vol 2021 ◽  
pp. 1-11
Author(s):  
Tao Liu ◽  
Yuejun Fang
Keyword(s):  
Data Mining ◽  
Colon Cancer ◽  
Normal Tissue ◽  
Predictive Ability ◽  
Gene Interaction ◽  
Notch Signaling Pathway ◽  
Cancer Tissue ◽  
Gamma Aminobutyric Acid ◽  
Colon Cancer Tissue ◽  
Go Annotation

Colon cancer is one of the top five cancers with the highest incidence rate in the world. In order to better understand the pathogenesis and progression of colon cancer, it is still necessary to investigate the abnormally expressed genes in cancer tissue. In this study, the Oncomine database was used for expression analysis, and it was found that the expression level of gamma-aminobutyric acid type A receptor subunit delta (GABRD) gene was upregulated in colon cancer tissue compared with that in normal tissue. UALCAN was used to analyze the expression of GABRD in different groups of age, gender, cancer stage, N stage, and histological subtype. Then, it was also found that the expression of GABRD in each subgroup of colon cancer tissue was all high compared with that in normal tissue. LinkedOmics was used to screen out the differentially expressed genes related to GABRD expression in colon cancer. GO annotation and KEGG pathway enrichment analyses found that the correlated genes may be related to breast cancer, human papillomavirus infection, Notch signaling pathway, and other pathways. Thereafter, GSEA was performed to obtain GABRD-related kinases, miRNAs, and transcription factors, and gene interaction networks were constructed. It was found that GABRD may be involved in cell cycle regulation. Finally, websites like GEPIA were used to detect the predictive ability of GABRD on the prognosis of patients with colon cancer. Kaplan-Meier analysis suggested that the upregulation of GABRD expression was related to the poor prognosis of patients with colon cancer. Overall, in this study, the potential role and prognostic ability of GABRD in colon cancer were explored through data mining, which can be a clue for further research on GABRD.

Abstract 4944: Detection of functional P-selectin ligands expressed on colon cancer tissue using a novel flow-based assay

2016 ◽  
Author(s):  
Eric W. Martin ◽  
Ramiro Malgor ◽  
Vicente A. Resto ◽  
Douglas J. Goetz ◽  
Monica M. Burdick
Keyword(s):  
Colon Cancer ◽  
Cancer Tissue ◽  
Colon Cancer Tissue ◽  
Selectin Ligands

scholarly journals Identification of alternatively spliced TIMP-1 mRNA in cancer cell lines and colon cancer tissue

2007 ◽  
Vol 1 (2) ◽  
pp. 205-215 ◽  
Author(s):  
P.A. Usher ◽  
A.M. Sieuwerts ◽  
A. Bartels ◽  
U. Lademann ◽  
H.J. Nielsen ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Cell Lines ◽  
Cancer Cell ◽  
Cancer Cell Lines ◽  
Cancer Tissue ◽  
Colon Cancer Tissue ◽  
Alternatively Spliced

Free-radical processes in multifocal colon cancer tissue.

2014 ◽  
Vol 32 (15_suppl) ◽  
pp. e14636-e14636
Author(s):  
Michail L. Maleyko ◽  
Elena Frantsiyants ◽  
Yuri Gevorkyan ◽  
Ekaterina Komarova ◽  
Andrey Dashkov ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Free Radical ◽  
Cancer Tissue ◽  
Colon Cancer Tissue ◽  
Free Radical Processes ◽  
Radical Processes

Adherent E. coli from colon cancer tissue can induce IL-8 release and COX2 expression

2003 ◽  
Vol 124 (4) ◽  
pp. A484
Author(s):  
Helen Martin ◽  
Barry Campbell ◽  
Manu Nayar ◽  
Helen Williams ◽  
Charles A. Hart ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Cancer Tissue ◽  
Colon Cancer Tissue ◽  
E Coli ◽  
Cox2 Expression

scholarly journals Antibody validation and scoring guidelines for ABCG2 immunohistochemical staining in formalin-fixed paraffin-embedded colon cancer tissue

2016 ◽  
Vol 6 (1) ◽  
Author(s):  
Camilla Natasha Cederbye ◽  
Jesper Andreas Palshof ◽  
Tine Plato Hansen ◽  
Anne Katrine Duun-Henriksen ◽  
Dorte Linnemann ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Immunohistochemical Staining ◽  
Cancer Tissue ◽  
Colon Cancer Tissue ◽  
Formalin Fixed Paraffin ◽  
Formalin Fixed Paraffin Embedded ◽  
Antibody Validation ◽  
Formalin Fixed

Virtual staining of colon cancer tissue by label-free Raman micro-spectroscopy

The Analyst ◽  
2017 ◽  
Vol 142 (8) ◽  
pp. 1207-1215 ◽  
Author(s):  
D. Petersen ◽  
L. Mavarani ◽  
D. Niedieker ◽  
E. Freier ◽  
A. Tannapfel ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Spectral Imaging ◽  
Cancer Tissue ◽  
Label Free ◽  
Colon Cancer Tissue ◽  
Free Classification ◽  
Raman Spectral

The great capability of virtual staining for label-free classification of colon cancer tissue has been demonstrated via Raman spectral imaging.

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