To gate or not to gate: an evaluation of respiratory gating techniques to improve volume measurement of murine lung tumors in micro-CT imaging

Author(s):  
Stephanie Blocker ◽  
Matthew Holbrook ◽  
Yvonne M. Mowery ◽  
Cristian T. Badea
PLoS ONE ◽  
2020 ◽  
Vol 15 (2) ◽  
pp. e0225019 ◽  
Author(s):  
S. J. Blocker ◽  
M. D. Holbrook ◽  
Y. M. Mowery ◽  
D. C. Sullivan ◽  
C. T. Badea

BIO-PROTOCOL ◽  
2015 ◽  
Vol 5 (24) ◽  
Author(s):  
Chiara Ambrogio ◽  
Juan C�mara ◽  
Patricia Nieto ◽  
David Santamar�a ◽  
Francisca Mulero
Keyword(s):  

2014 ◽  
Author(s):  
Joshua K. Y. Swee ◽  
Clare Sheridan ◽  
Elza de Bruin ◽  
Julian Downward ◽  
Francois Lassailly ◽  
...  

2011 ◽  
Author(s):  
Laurel M. Burk ◽  
Yueh Z. Lee ◽  
Samuel Heathcote ◽  
Ko-han Wang ◽  
William Y. Kim ◽  
...  

2006 ◽  
Author(s):  
Eman Namati ◽  
Deokiee Chon ◽  
Jacqueline Thiesse ◽  
Geoffrey McLennan ◽  
Jered Sieren ◽  
...  

Author(s):  
Sebastian Halm ◽  
David Haberthür ◽  
Elisabeth Eppler ◽  
Valentin Djonov ◽  
Andreas Arnold

Abstract Introduction This pilot study explores whether a human Thiel-embalmed temporal bone is suitable for generating an accurate and complete data set with micro-computed tomography (micro-CT) and whether solid iodine-staining improves visualization and facilitates segmentation of middle ear structures. Methods A temporal bone was used to verify the accuracy of the imaging by first digitally measuring the stapes on the tomography images and then physically under the microscope after removal from the temporal bone. All measurements were compared with literature values. The contralateral temporal bone was used to evaluate segmentation and three-dimensional (3D) modeling after iodine staining and micro-CT scanning. Results The digital and physical stapes measurements differed by 0.01–0.17 mm or 1–19%, respectively, but correlated well with the literature values. Soft tissue structures were visible in the unstained scan. However, iodine staining increased the contrast-to-noise ratio by a factor of 3.7 on average. The 3D model depicts all ossicles and soft tissue structures in detail, including the chorda tympani, which was not visible in the unstained scan. Conclusions Micro-CT imaging of a Thiel-embalmed temporal bone accurately represented the entire anatomy. Iodine staining considerably increased the contrast of soft tissues, simplified segmentation and enabled detailed 3D modeling of the middle ear.


2013 ◽  
Vol 35 (12) ◽  
pp. 1793-1800 ◽  
Author(s):  
D. Sreenivasan ◽  
M. Watson ◽  
K. Callon ◽  
M. Dray ◽  
R. Das ◽  
...  

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