scholarly journals A dual-wavelength spread spectrum-based spectroscopic system For time-domain near-infrared diffuse optical imaging

2019 ◽  
Author(s):  
Konstantinos I. Papadimitriou ◽  
Jeremy C. Hebden ◽  
Simon R. Arridge ◽  
Samuel Powell
Keyword(s):  
Optical Imaging ◽  
Time Domain ◽  
Spread Spectrum ◽  
Near Infrared ◽  
Dual Wavelength ◽  
Diffuse Optical Imaging

scholarly journals A spread spectrum approach to time-domain near-infrared diffuse optical imaging using inexpensive optical transceiver modules

2018 ◽  
Vol 9 (6) ◽  
pp. 2648 ◽  
Author(s):  
Konstantinos I. Papadimitriou ◽  
Laura A. Dempsey ◽  
Jeremy C. Hebden ◽  
Simon R. Arridge ◽  
Samuel Powell
Keyword(s):  
Optical Imaging ◽  
Time Domain ◽  
Spread Spectrum ◽  
Near Infrared ◽  
Diffuse Optical Imaging

scholarly journals Time-Domain Diffuse Optical Imaging of Tissue by Non-contact Scanning

2015 ◽  
pp. 561-585 ◽  
Author(s):  
Heidrun Wabnitz ◽  
Mikhail Mazurenka ◽  
Laura Di Sieno ◽  
Gianluca Boso ◽  
Wolfgang Becker ◽  
...  
Keyword(s):  
Optical Imaging ◽  
Time Domain ◽  
Diffuse Optical Imaging

scholarly journals In Vivo Resolution of Multiexponential Decays of Multiple Near-Infrared Molecular Probes by Fluorescence Lifetime-Gated Whole-Body Time-Resolved Diffuse Optical Imaging

2007 ◽  
Vol 6 (4) ◽  
pp. 7290.2007.00020 ◽  
Author(s):  
Walter Akers ◽  
Frederic Lesage ◽  
Dewey Holten ◽  
Samuel Achilefu
Keyword(s):  
Optical Imaging ◽  
Fluorescence Lifetime ◽  
Fluorescence Intensity ◽  
Near Infrared ◽  
Molecular Probes ◽  
Whole Body ◽  
Diffuse Optical Imaging ◽  
Fluorescence Lifetimes ◽  
Time Resolved

The biodistribution of two near-infrared fluorescent agents was assessed in vivo by time-resolved diffuse optical imaging. Bacteriochlorophyll a (BC) and cypate-glysine-arginine-aspartic acid-serine-proline-lysine-OH (Cyp-GRD) were administered separately or combined to mice with subcutaneous xenografts of human breast adenocarcinoma and slow-release estradiol pellets for improved tumor growth. The same excitation (780 nm) and emission (830 nm) wavelengths were used to image the distinct fluorescence lifetime distribution of the fluorescent molecular probes in the mouse cancer model. Fluorescence intensity and lifetime maps were reconstructed after raster-scanning whole-body regions of interest by time-correlated single-photon counting. Each captured temporal point-spread function (TPSF) was deconvolved using both a single and a multiexponental decay model to best determine the measured fluorescence lifetimes. The relative signal from each fluorophore was estimated for any region of interest included in the scanned area. Deconvolution of the individual TPSFs from whole-body fluorescence intensity scans provided corresponding lifetime images for comparing individual component biodistribution. In vivo fluorescence lifetimes were determined to be 0.8 ns (Cyp-GRD) and 2 ns (BC). This study demonstrates that the relative biodistribution of individual fluorophores with similar spectral characteristics can be compartmentalized by using the time-domain fluorescence lifetime gating method.

Diffuse optical imaging

2009 ◽  
Vol 367 (1900) ◽  
pp. 3055-3072 ◽  
Author(s):  
Adam Gibson ◽  
Hamid Dehghani
Keyword(s):  
Optical Imaging ◽  
Near Infrared ◽  
State Of The Art ◽  
Imaging Technique ◽  
Multimodality Imaging ◽  
Natural Extension ◽  
Psychological Research ◽  
Functional Brain Imaging ◽  
Diffuse Optical Imaging ◽  
Image Reconstruction Techniques

Diffuse optical imaging is a medical imaging technique that is beginning to move from the laboratory to the hospital. It is a natural extension of near-infrared spectroscopy (NIRS), which is now used in certain niche applications clinically and particularly for physiological and psychological research. Optical imaging uses sophisticated image reconstruction techniques to generate images from multiple NIRS measurements. The two main clinical applications—functional brain imaging and imaging for breast cancer—are reviewed in some detail, followed by a discussion of other issues such as imaging small animals and multimodality imaging. We aim to review the state of the art of optical imaging.

Time domain diffuse optical imaging and spectroscopy of breast

2011 ◽  
Author(s):  
Paola Taroni ◽  
Antonio Pifferi ◽  
Giovanna Quarto ◽  
Alessandro Torricelli ◽  
Rinaldo Cubeddu ◽  
...  
Keyword(s):  
Optical Imaging ◽  
Time Domain ◽  
Diffuse Optical Imaging ◽  
Imaging And Spectroscopy

scholarly journals Dual wavelength tumor targeting for detection of hypopharyngeal cancer using near-infrared optical imaging in an animal model

2012 ◽  
Vol 131 (7) ◽  
pp. 1633-1640 ◽  
Author(s):  
Stijn Keereweer ◽  
Isabel M. Mol ◽  
Alexander L. Vahrmeijer ◽  
Pieter B.A.A. Van Driel ◽  
Robert J. Baatenburg de Jong ◽  
...  
Keyword(s):  
Animal Model ◽  
Optical Imaging ◽  
Tumor Targeting ◽  
Near Infrared ◽  
Hypopharyngeal Cancer ◽  
Dual Wavelength

Near-Infrared Optical Imaging Based on Time-Domain Photon Information

2019 ◽  
Vol 39 (4) ◽  
pp. 0412011
Author(s):  
乔要宾 Qiao Yaobin ◽  
陈辛 Chen Xin ◽  
郭正玉 Guo Zhengyu
Keyword(s):  
Optical Imaging ◽  
Time Domain ◽  
Near Infrared
Sign in / Sign up

Export Citation Format

Share Document