Nanophotonic structures for highly efficient on-chip optical manipulation

2018 ◽  
Author(s):  
Po-Tsung Lee ◽  
Tsan-Wen Lu ◽  
Pin-Tso Lin ◽  
Chia-Yu Lin ◽  
Chia-Yang Tsai
Keyword(s):  
Optical Manipulation ◽  
Highly Efficient ◽  
On Chip ◽  
Nanophotonic Structures

scholarly journals 3D printed microfluidic lab-on-a-chip device for fiber-based dual beam optical manipulation

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Haoran Wang ◽  
Anton Enders ◽  
John-Alexander Preuss ◽  
Janina Bahnemann ◽  
Alexander Heisterkamp ◽  
...  
Keyword(s):  
Optical Fibers ◽  
Single Cells ◽  
Lab On A Chip ◽  
Cost Effective ◽  
Optical Manipulation ◽  
Hydrodynamic Focusing ◽  
Trapping Region ◽  
Dual Beam ◽  
3D Printed ◽  
On Chip

Abstract3D printing of microfluidic lab-on-a-chip devices enables rapid prototyping of robust and complex structures. In this work, we designed and fabricated a 3D printed lab-on-a-chip device for fiber-based dual beam optical manipulation. The final 3D printed chip offers three key features, such as (1) an optimized fiber channel design for precise alignment of optical fibers, (2) an optically clear window to visualize the trapping region, and (3) a sample channel which facilitates hydrodynamic focusing of samples. A square zig–zag structure incorporated in the sample channel increases the number of particles at the trapping site and focuses the cells and particles during experiments when operating the chip at low Reynolds number. To evaluate the performance of the device for optical manipulation, we implemented on-chip, fiber-based optical trapping of different-sized microscopic particles and performed trap stiffness measurements. In addition, optical stretching of MCF-7 cells was successfully accomplished for the purpose of studying the effects of a cytochalasin metabolite, pyrichalasin H, on cell elasticity. We observed distinct changes in the deformability of single cells treated with pyrichalasin H compared to untreated cells. These results demonstrate that 3D printed microfluidic lab-on-a-chip devices offer a cost-effective and customizable platform for applications in optical manipulation.

A Novel Hybrid Cache Coherence with Global Snooping for Many-core Architectures

2022 ◽  
Vol 27 (1) ◽  
pp. 1-31
Author(s):  
Sri Harsha Gade ◽  
Sujay Deb
Keyword(s):  
Lower Energy ◽  
Cache Coherence ◽  
Network On Chip ◽  
Highly Efficient ◽  
Wireless Links ◽  
Coherence Protocols ◽  
High Area ◽  
On Chip ◽  
Many Core ◽  
Clustered Network

Cache coherence ensures correctness of cached data in multi-core processors. Traditional implementations of existing protocols make them unscalable for many core architectures. While snoopy coherence requires unscalable ordered networks, directory coherence is weighed down by high area and energy overheads. In this work, we propose Wireless-enabled Share-aware Hybrid (WiSH) to provide scalable coherence in many core processors. WiSH implements a novel Snoopy over Directory protocol using on-chip wireless links and hierarchical, clustered Network-on-Chip to achieve low-overhead and highly efficient coherence. A local directory protocol maintains coherence within a cluster of cores, while coherence among such clusters is achieved through global snoopy protocol. The ordered network for global snooping is provided through low-latency and low-energy broadcast wireless links. The overheads are further reduced through share-aware cache segmentation to eliminate coherence for private blocks. Evaluations show that WiSH reduces traffic by and runtime by , while requiring smaller storage and lower energy as compared to existing hierarchical and hybrid coherence protocols. Owing to its modularity, WiSH provides highly efficient and scalable coherence for many core processors.

Machined multicore optical fibres for on-chip optical manipulation

2017 ◽  
Author(s):  
Georgia Anastasiadi ◽  
William N. MacPherson ◽  
Lynn Paterson ◽  
Mark Leonard
Keyword(s):  
Optical Manipulation ◽  
Optical Fibres ◽  
On Chip

scholarly journals A Hybrid Integration Strategy for Compact, Broadband, and Highly Efficient Millimeter-Wave On-Chip Antennas

2019 ◽  
Vol 18 (11) ◽  
pp. 2424-2428 ◽  
Author(s):  
Quinten Van den Brande ◽  
Ad C. F. Reniers ◽  
Bart Smolders ◽  
Bart Kuyken ◽  
Dries Vande Ginste ◽  
...  
Keyword(s):  
Millimeter Wave ◽  
Hybrid Integration ◽  
Highly Efficient ◽  
Integration Strategy ◽  
On Chip

Planar Highly Efficient High-Gain 165 GHz On-Chip Antennas for Integrated Radar Sensors

2019 ◽  
Vol 18 (11) ◽  
pp. 2429-2433 ◽  
Author(s):  
Wael A. Ahmad ◽  
Maciej Kucharski ◽  
Adolfo Di Serio ◽  
Herman Jalli Ng ◽  
Christian Waldschmidt ◽  
...  
Keyword(s):  
High Gain ◽  
Radar Sensors ◽  
Highly Efficient ◽  
On Chip
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