Multidistance time domain diffuse optical spectroscopy in the assessment of abdominal fat heterogeneity

2018 ◽  
Author(s):  
Pranav Lanka ◽  
Andrea Farina ◽  
Sanathana Konugolu Venkata Sekar ◽  
Claudia Guadagno ◽  
Lorenzo Spinelli ◽  
...  
Keyword(s):  
Optical Spectroscopy ◽  
Time Domain ◽  
Abdominal Fat ◽  
Diffuse Optical Spectroscopy

scholarly journals Special Issue on New Horizons in Time Domain Diffuse Optical Spectroscopy and Imaging

2020 ◽  
Vol 10 (8) ◽  
pp. 2752
Author(s):  
Yoko Hoshi
Keyword(s):  
Infrared Spectroscopy ◽  
Optical Spectroscopy ◽  
Near Infrared Spectroscopy ◽  
Time Domain ◽  
Near Infrared ◽  
Special Issue ◽  
Diffuse Optical Spectroscopy ◽  
New Horizons

In 1977, Jöbsis first described the in vivo application of near-infrared spectroscopy (NIRS) [...]

scholarly journals Non-invasive investigation of adipose tissue by time domain diffuse optical spectroscopy

2020 ◽  
Vol 11 (5) ◽  
pp. 2779
Author(s):  
Pranav Lanka ◽  
Agnese Segala ◽  
Andrea Farina ◽  
Sanathana Konugolu Venkata Sekar ◽  
Enzo Nisoli ◽  
...  
Keyword(s):  
Adipose Tissue ◽  
Optical Spectroscopy ◽  
Time Domain ◽  
Diffuse Optical Spectroscopy ◽  
Non Invasive

Time-domain diffuse optical spectroscopy beyond 1100 nm: initial feasibility study

2011 ◽  
Author(s):  
Antonio Pifferi ◽  
Ilaria Bargigia ◽  
Paola Taroni ◽  
Andrea Farina ◽  
Rinaldo Cubeddu
Keyword(s):  
Optical Spectroscopy ◽  
Feasibility Study ◽  
Time Domain ◽  
Diffuse Optical Spectroscopy

Time-domain diffuse optical spectroscopy beyond 1100 nm:initial feasibility study

2011 ◽  
Author(s):  
Antonio Pifferi ◽  
Ilaria Bargigia ◽  
Paola Taroni ◽  
Andrea Farina ◽  
Rinaldo Cubeddua
Keyword(s):  
Optical Spectroscopy ◽  
Feasibility Study ◽  
Time Domain ◽  
Diffuse Optical Spectroscopy

Time-domain diffuse optical spectroscopy up to 1700 nm using an InGaAs/InP single-photon avalanche diode

2011 ◽  
Author(s):  
Ilaria Bargigia ◽  
Alberto Tosi ◽  
Andrea Farina ◽  
Andrea Bassi ◽  
Paola Taroni ◽  
...  
Keyword(s):  
Optical Spectroscopy ◽  
Time Domain ◽  
Single Photon ◽  
Diffuse Optical Spectroscopy ◽  
Avalanche Diode

scholarly journals Comparison of Lipid and Water Contents by Time-domain Diffuse Optical Spectroscopy and Dual-energy Computed Tomography in Breast Cancer Patients

2019 ◽  
Vol 9 (7) ◽  
pp. 1482 ◽  
Author(s):  
Etsuko Ohmae ◽  
Nobuko Yoshizawa ◽  
Kenji Yoshimoto ◽  
Maho Hayashi ◽  
Hiroko Wada ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Computed Tomography ◽  
Cancer Patients ◽  
Optical Spectroscopy ◽  
Time Domain ◽  
Dual Energy ◽  
Breast Cancer Patients ◽  
Diffuse Optical Spectroscopy ◽  
Dual Energy Computed Tomography ◽  
Water Contents

We previously compared time-domain diffuse optical spectroscopy (TD-DOS) with magnetic resonance imaging (MRI) using various water/lipid phantoms. However, it is difficult to conduct similar comparisons in the breast, because of measurement differences due to modality-dependent differences in posture. Dual-energy computed tomography (DECT) examination is performed in the same supine position as a TD-DOS measurement. Therefore, we first verified the accuracy of the measured fat fraction of fibroglandular tissue in the normal breast on DECT by comparing it with MRI in breast cancer patients (n = 28). Then, we compared lipid and water signals obtained in TD-DOS and DECT from normal and tumor-tissue regions (n = 16). The TD-DOS breast measurements were carried out using reflectance geometry with a source–detector separation of 3 cm. A semicircular region of interest (ROI), with a transverse diameter of 3 cm and a depth of 2 cm that included the breast surface, was set on the DECT image. Although the measurement area differed between the modalities, the correlation coefficients of lipid and water signals between TD-DOS and DECT were rs = 0.58 (p < 0.01) and rs = 0.90 (p < 0.01), respectively. These results indicate that TD-DOS captures the characteristics of the lipid and water contents of the breast.

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