Smart routing logic for highly efficient readout of single photon avalanche diode arrays for time-resolved imaging

2018 ◽  
Author(s):  
Alessandro Cominelli ◽  
Giulia Acconcia ◽  
Massimo Ghioni ◽  
Ivan Rech
Keyword(s):  
Single Photon ◽  
Time Resolved ◽  
Avalanche Diode ◽  
Highly Efficient ◽  
Time Resolved Imaging

scholarly journals Gated SPAD Arrays for Single-Photon Time-Resolved Imaging and Spectroscopy

2019 ◽  
Vol 11 (6) ◽  
pp. 1-10 ◽  
Author(s):  
Enrico Conca ◽  
Iris Cusini ◽  
Fabio Severini ◽  
Rudi Lussana ◽  
Franco Zappa ◽  
...  
Keyword(s):  
Single Photon ◽  
Time Resolved ◽  
Imaging And Spectroscopy ◽  
Time Resolved Imaging

scholarly journals Single-photon Coulomb explosion of methanol using broad bandwidth ultrafast EUV pulses

2017 ◽  
Vol 19 (21) ◽  
pp. 13488-13495 ◽  
Author(s):  
Itamar Luzon ◽  
Krishna Jagtap ◽  
Ester Livshits ◽  
Oleg Lioubashevski ◽  
Roi Baer ◽  
...  
Keyword(s):  
Single Photon ◽  
Coulomb Explosion ◽  
Ultrafast Dynamics ◽  
Time Resolved ◽  
Broad Bandwidth ◽  
Time Resolved Imaging

Single-photon Coulomb explosion of methanol using broad bandwidth ultrafast EUV pulses towards achieving time resolved imaging of ultrafast dynamics.

scholarly journals Time-Resolved Diffuse Optical Spectroscopy up to 1700 nm by Means of a Time-Gated InGaAs/InP Single-Photon Avalanche Diode

2012 ◽  
Vol 66 (8) ◽  
pp. 944-950 ◽  
Author(s):  
Ilaria Bargigia ◽  
Alberto Tosi ◽  
Andrea Bahgat Shehata ◽  
Adriano Della Frera ◽  
Andrea Farina ◽  
...  
Keyword(s):  
Optical Spectroscopy ◽  
Single Photon ◽  
Time Resolved ◽  
Diffuse Optical Spectroscopy ◽  
Avalanche Diode

Time-resolved imaging of fluorescent inclusions in optically turbid medium — phantom study

2010 ◽  
Vol 18 (1) ◽  
Author(s):  
M. Kacprzak ◽  
A. Liebert ◽  
P. Sawosz ◽  
N. Żołek ◽  
D. Milej ◽  
...  
Keyword(s):  
Optical Properties ◽  
Imaging System ◽  
Single Photon ◽  
Photon Counting ◽  
Turbid Medium ◽  
Time Resolved ◽  
Excitation Light ◽  
Time Resolved Imaging ◽  
Fish Tank ◽  
Surrounding Liquid

AbstractWe present results of application of a time-resolved optical system for imaging of fluorescence excited in an inclusion containing indocyanine green (ICG), and located in optically turbid medium. The developed imaging system enabled simultaneous acquisition of fluorescence and diffusive reflectance. Eight independent time-resolved measurement channels based on time-correlated single photon counting technique were applied. In four of these channels, used for the fluorescence detection, sets of filters were applied in order to block the excitation light. Fast optomechanical switches allowed us to illuminate sequentially nine different spots on the surface of the studied object and finally 4×4 pixels maps at excitation and emission wavelengths were obtained. A liquid phantom used in this study consists of the fish tank filed with a solution ofmilk and water with black ink added to obtain optical properties in the range of the optical properties typical for the living tissue. A gel ball of a diameter of 5 mm with precisely controlled concentration of ICG was immersed in the liquid. The measurements were performed for inclusion located at different depths and for various ICG concentrations in the gel ball and in the surrounding liquid. The recorded distributions of times of arrival (DTA) of fluorescence photons and times of flight (DTOF) of diffusely reflected photons were analyzed by calculation of their statistical moments. We observed specific changes in moments of the measured DTAs as a function of depth of immersion of the fluorescent inclusion in the medium. We noted also that the changes of moments depend significantly on concentration of the dye in the fluorescence inclusion as well as in the surrounding liquid.

scholarly journals Single-photon avalanche diode imagers in biophotonics: review and outlook

2019 ◽  
Vol 8 (1) ◽  
Author(s):  
Claudio Bruschini ◽  
Harald Homulle ◽  
Ivan Michel Antolovic ◽  
Samuel Burri ◽  
Edoardo Charbon
Keyword(s):  
Single Photon ◽  
Photon Counting ◽  
Super Resolution ◽  
Cmos Technology ◽  
Time Resolved ◽  
Avalanche Diode ◽  
The Past ◽  
Fast Pace ◽  
On Chip ◽  
Super Resolution Microscopy

Abstract Single-photon avalanche diode (SPAD) arrays are solid-state detectors that offer imaging capabilities at the level of individual photons, with unparalleled photon counting and time-resolved performance. This fascinating technology has progressed at a very fast pace in the past 15 years, since its inception in standard CMOS technology in 2003. A host of architectures have been investigated, ranging from simpler implementations, based solely on off-chip data processing, to progressively “smarter” sensors including on-chip, or even pixel level, time-stamping and processing capabilities. As the technology has matured, a range of biophotonics applications have been explored, including (endoscopic) FLIM, (multibeam multiphoton) FLIM-FRET, SPIM-FCS, super-resolution microscopy, time-resolved Raman spectroscopy, NIROT and PET. We will review some representative sensors and their corresponding applications, including the most relevant challenges faced by chip designers and end-users. Finally, we will provide an outlook on the future of this fascinating technology.

scholarly journals Chemical imaging of human teeth by a time-resolved Raman spectrometer based on a CMOS single-photon avalanche diode line sensor

The Analyst ◽  
2019 ◽  
Vol 144 (20) ◽  
pp. 6089-6097 ◽  
Author(s):  
Jere Kekkonen ◽  
Mikko A. J. Finnilä ◽  
Jarkko Heikkilä ◽  
Vuokko Anttonen ◽  
Ilkka Nissinen
Keyword(s):  
Single Photon ◽  
Chemical Imaging ◽  
Spectral Quality ◽  
Human Teeth ◽  
Time Resolved ◽  
Avalanche Diode ◽  
Raman Spectrometer

Improvement to the spectral quality of Rama images of human teeth were achieved with a time-resolved CMOS SPAD-based Raman spectrometer.

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