Bare laser-synthesized Si nanoparticles as functional elements for chitosan nanofiber-based tissue engineering platforms

2018 ◽  
Author(s):  
Gleb Tselikov ◽  
Yury V. Ryabchikov ◽  
Anton A. Popov ◽  
Igor Chourpa ◽  
Amir W. Fahmi ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Functional Elements ◽  
Si Nanoparticles ◽  
Chitosan Nanofiber

scholarly journals Recent Advances in Laser-Ablative Synthesis of Bare Au and Si Nanoparticles and Assessment of Their Prospects for Tissue Engineering Applications

2018 ◽  
Vol 19 (6) ◽  
pp. 1563 ◽  
Author(s):  
Ahmed Al-Kattan ◽  
Viraj Nirwan ◽  
Anton Popov ◽  
Yury Ryabchikov ◽  
Gleb Tselikov ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Engineering Applications ◽  
Recent Advances ◽  
Si Nanoparticles

scholarly journals Toward multifunctional hybrid platforms for tissue engineering based on chitosan(PEO) nanofibers functionalized by bare laser-synthesized Au and Si nanoparticles

RSC Advances ◽  
2017 ◽  
Vol 7 (50) ◽  
pp. 31759-31766 ◽  
Author(s):  
Ahmed Al-Kattan ◽  
Viraj P. Nirwan ◽  
Emilie Munnier ◽  
Igor Chourpa ◽  
Amir Fahmi ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Physicochemical Properties ◽  
Si Nanoparticles

Exhibiting a variety of unique optical, structural and physicochemical properties, laser-synthesized nanomaterials have become increasingly popular during recent years in a variety of biomedical, catalytic, photovoltaic and other applications.

scholarly journals Electrospun Biomaterials from Chitosan Blends Applied as Scaffold for Tissue Regeneration

Polymers ◽  
2021 ◽  
Vol 13 (7) ◽  
pp. 1037
Author(s):  
Christian Enrique Garcia Garcia ◽  
Frédéric Bossard ◽  
Marguerite Rinaudo
Keyword(s):  
Tissue Engineering ◽  
Chitosan Film ◽  
Electrospinning Technique ◽  
Force Microscopy ◽  
Atomic Force ◽  
Chitosan Nanofiber ◽  
Chitosan Blends ◽  
Nanofiber Mats ◽  
Cell Force

Our objective in this work was to summarize the main results obtained in processing pure chitosan and chitosan/hyaluronan complex in view of biomedical applications, taking advantage of their original properties. In addition, an electrospinning technique was selected to prepare nanofiber mats well adapted for tissue engineering in relation to the large porosity of the materials, allowing an exchange with the environment. The optimum conditions for preparation of purified and stable nanofibers in aqueous solution and phosphate buffer pH = 7.4 are described. Their mechanical properties and degree of swelling are given. Then, the prepared biomaterials are investigated to test their advantage for chondrocyte development after comparison of nanofiber mats and uniform films. For that purpose, the adhesion of cells is studied by atomic force microscopy (AFM) using single-cell force spectroscopy, showing the good adhesion of chondrocytes on chitosan. At the end, adhesion and proliferation of chondrocytes in vitro are examined and clearly show the interest of chitosan nanofiber mats compared to chitosan film for potential application in tissue engineering.

Electrospun chitosan nanofiber for tissue engineering

2010 ◽  
Author(s):  
Yun Mi Kang ◽  
Jae Hoon Ko ◽  
E Sle Kim ◽  
Gyeong Hae Kim ◽  
Goh Woon Park ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Chitosan Nanofiber

Decellularized bone extracellular matrix in skeletal tissue engineering

2020 ◽  
Vol 48 (3) ◽  
pp. 755-764
Author(s):  
Benjamin B. Rothrauff ◽  
Rocky S. Tuan
Keyword(s):  
Tissue Engineering ◽  
Bone Regeneration ◽  
Tissue Regeneration ◽  
Animal Studies ◽  
Tumor Resection ◽  
Regenerative Capacity ◽  
Skeletal Tissue ◽  
Large Bone

Bone possesses an intrinsic regenerative capacity, which can be compromised by aging, disease, trauma, and iatrogenesis (e.g. tumor resection, pharmacological). At present, autografts and allografts are the principal biological treatments available to replace large bone segments, but both entail several limitations that reduce wider use and consistent success. The use of decellularized extracellular matrices (ECM), often derived from xenogeneic sources, has been shown to favorably influence the immune response to injury and promote site-appropriate tissue regeneration. Decellularized bone ECM (dbECM), utilized in several forms — whole organ, particles, hydrogels — has shown promise in both in vitro and in vivo animal studies to promote osteogenic differentiation of stem/progenitor cells and enhance bone regeneration. However, dbECM has yet to be investigated in clinical studies, which are needed to determine the relative efficacy of this emerging biomaterial as compared with established treatments. This mini-review highlights the recent exploration of dbECM as a biomaterial for skeletal tissue engineering and considers modifications on its future use to more consistently promote bone regeneration.

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