Far-field wide-field label-free nanoscale imaging based on full-angle evanescent wave illumination (Conference Presentation)

Author(s):  
Qing Yang
2019 ◽  
Vol 9 (18) ◽  
pp. 3834
Author(s):  
Zhang ◽  
Li ◽  
Godavarthi ◽  
Ruan

Tomographic diffractive microscopy (TDM) is a label-free, far-field, super-resolution microscope. The significant difference between TDM and wide-field microscopy is that in TDM the sample is illuminated from various directions with a coherent collimated beam and the complex diffracted field is collected from many scattered angles. By utilizing inversion procedures, the permittivity/refractive index of investigated samples can be retrieved from the measured diffracted field to reconstruct the geometrical parameters of a sample. TDM opens up new opportunities to study biological samples and nano-structures and devices, which require resolution beyond the Rayleigh limit. In this review, we describe the principles and recent advancements of TDM and also give the perspectives of this fantastic microscopy technique.


2018 ◽  
Vol 114 (3) ◽  
pp. 504a-505a
Author(s):  
Mohammed Mahamdeh ◽  
Steve Simmert ◽  
Anna Łuchniak ◽  
Erik Schäffer ◽  
Jonathon Howard

2019 ◽  
Vol 5 (3) ◽  
pp. eaav5335 ◽  
Author(s):  
Yan Kuai ◽  
Junxue Chen ◽  
Xi Tang ◽  
Yifeng Xiang ◽  
Fengya Lu ◽  
...  

Surface plasmon resonance microscopy (SPRM) with single-direction illumination is a powerful platform for biomedical imaging because of its wide-field, label-free, and high-surface-sensitivity imaging capabilities. However, two disadvantages prevent wider use of SPRM. The first is its poor spatial resolution that can be as large as several micrometers. The second is that SPRM requires use of metal films as sample substrates; this introduces working wavelength limitations. In addition, cell culture growth on metal films is not as universally available as growth on dielectric substrates. Here we show that use of azimuthal rotation illumination allows SPRM spatial resolution to be enhanced by up to an order of magnitude. The metal film can also be replaced by a dielectric multilayer and then a different label-free surface-sensitive photonic microscopy is developed, which has more choices in terms of the working wavelength, polarization, and imaging section, and will bring opportunities for applications in biology.


2018 ◽  
Vol 27 (11) ◽  
pp. 118704 ◽  
Author(s):  
Xiaowei Liu ◽  
Chao Meng ◽  
Xuechu Xu ◽  
Mingwei Tang ◽  
Chenlei Pang ◽  
...  

ChemPhysChem ◽  
2008 ◽  
Vol 9 (17) ◽  
pp. 2480-2485 ◽  
Author(s):  
Magnus Brändén ◽  
Sara Dahlin ◽  
Fredrik Höök

2018 ◽  
Vol 5 (6) ◽  
pp. 1870036
Author(s):  
Anna Khimchenko ◽  
Christos Bikis ◽  
Alexandra Pacureanu ◽  
Simone E. Hieber ◽  
Peter Thalmann ◽  
...  

2017 ◽  
Vol 118 (7) ◽  
Author(s):  
Xiaowei Liu ◽  
Cuifang Kuang ◽  
Xiang Hao ◽  
Chenlei Pang ◽  
Pengfei Xu ◽  
...  
Keyword(s):  

2017 ◽  
Vol 42 (21) ◽  
pp. 4569 ◽  
Author(s):  
Chenlei Pang ◽  
Xiaowei Liu ◽  
Minghua Zhuge ◽  
Xu Liu ◽  
Michael Geoffrey Somekh ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document