Near infrared spatial frequency domain fluorescence imaging of tumor phantoms containing erythrocyte-derived optical nanoplatforms

2018 ◽  
Author(s):  
Joshua M. Burns ◽  
Bahman Anvari ◽  
Elise Schaefer
Keyword(s):  
Spatial Frequency ◽  
Frequency Domain ◽  
Fluorescence Imaging ◽  
Near Infrared ◽  
Spatial Frequency Domain

scholarly journals Early stage dental caries detection using near infrared spatial frequency domain imaging

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Alistair D. Bounds ◽  
John M. Girkin
Keyword(s):  
Dental Caries ◽  
Spatial Frequency ◽  
Frequency Domain ◽  
Near Infrared ◽  
Early Stage ◽  
Infrared Light ◽  
Dental Tissue ◽  
Spatial Frequency Domain Imaging ◽  
Demineralized Enamel ◽  
Spatial Frequency Domain

AbstractEarly stage dental caries can be remineralized without the need for “drill-and-fill” treatments that are more invasive and less permanent. However, early stage caries lesions typically present as a white spot on a white background, resulting in many lesions only being identified after they have developed beyond the point of remineralization as cavities. We present a spatial frequency domain imaging technique to characterize the optical properties of dental tissue. This technique enables different dental tissue types (healthy enamel, healthy dentin and damaged or demineralized enamel) to be easily distinguished from one another and allows quantification of the reduced scattering coefficients of dental tissue. The use of near-infrared light at 850 nm allows high depth penetration into the tissue and suppression of absorption effects, ensuring only changes in the reduced scattering coefficient that result directly from demineralization of enamel are observed and simplifying the analysis method. This technique provides a tool to both guide the attention of dentists to areas of interest and potential demineralization, and to provide longitudinal quantified assessments to monitor caries lesion behaviour over time.

scholarly journals Quantitative subsurface spatial frequency‐domain fluorescence imaging for enhanced glioma resection

2019 ◽  
Vol 12 (5) ◽  
Author(s):  
Mira Sibai ◽  
Dennis J. Wirth ◽  
Frederic Leblond ◽  
David W. Roberts ◽  
Keith D. Paulsen ◽  
...  
Keyword(s):  
Spatial Frequency ◽  
Frequency Domain ◽  
Fluorescence Imaging ◽  
Glioma Resection ◽  
Spatial Frequency Domain

scholarly journals Preclinical evaluation of spatial frequency domain-enabled wide-field quantitative imaging for enhanced glioma resection

2017 ◽  
Vol 22 (7) ◽  
pp. 076007 ◽  
Author(s):  
Mira Sibai ◽  
Carl Fisher ◽  
Israel Veilleux ◽  
Jonathan T. Elliott ◽  
Frederic Leblond ◽  
...  
Keyword(s):  
Spatial Frequency ◽  
Frequency Domain ◽  
Quantitative Imaging ◽  
Wide Field ◽  
Preclinical Evaluation ◽  
Glioma Resection ◽  
Spatial Frequency Domain
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