In vivo imaging of colonic tumours with a near-infrared fluorescent probe targeted against a tumour-associated-mucin in a human colon cancer xenograft mouse model

2017 ◽  
Author(s):  
Ralph S. DaCosta
Keyword(s):  
Colon Cancer ◽  
Mouse Model ◽  
Fluorescent Probe ◽  
In Vivo Imaging ◽  
Near Infrared ◽  
Human Colon ◽  
Human Colon Cancer ◽  
Xenograft Mouse Model ◽  
Colonic Tumours

In vivo imaging of alkaline phosphatase in tumor-bearing mouse model by a promising near-infrared fluorescent probe

Talanta ◽  
2017 ◽  
Vol 175 ◽  
pp. 421-426 ◽  
Author(s):  
Hong-Wen Liu ◽  
Xiao-Xiao Hu ◽  
Longmin Zhu ◽  
Ke Li ◽  
Qiming Rong ◽  
...  
Keyword(s):  
Alkaline Phosphatase ◽  
Mouse Model ◽  
Fluorescent Probe ◽  
In Vivo Imaging ◽  
Near Infrared ◽  
Tumor Bearing Mouse ◽  
Tumor Bearing

Abstract 2258: Targeting MACC1: In vivo imaging of distant metastases reduction by MACC1-shRNA in human colon cancer xenografts

2010 ◽  
Author(s):  
Ulrike S. Stein ◽  
Ulrike Sack ◽  
Dennis Kobelt ◽  
Inken Kelch ◽  
Iduna Fichtner ◽  
...  
Keyword(s):  
Colon Cancer ◽  
In Vivo Imaging ◽  
Distant Metastases ◽  
Human Colon ◽  
Human Colon Cancer

scholarly journals A Natural Flavone Tricin from Grains Can Alleviate Tumor Growth and Lung Metastasis in Colorectal Tumor Mice

Molecules ◽  
2020 ◽  
Vol 25 (16) ◽  
pp. 3730
Author(s):  
Grace Yue ◽  
Si Gao ◽  
Julia Lee ◽  
Yuk-Yu Chan ◽  
Eric Wong ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Mouse Model ◽  
Tumor Growth ◽  
Lung Metastasis ◽  
Suppressor Cells ◽  
Human Colon ◽  
Human Colon Cancer ◽  
Imaging Results ◽  
Phosphorylated Akt

Tricin, a flavone isolated from rice bran, has been shown to be chemopreventive in a colorectal cancer (CRC) mouse model. This study aimed to illustrate the inhibitory activities of tricin in colon cancer cells and in a metastatic CRC mouse model. BALB/c mice injected with mouse Colon26-Luc cells into the rectum wall were treated with tricin (37.5 mg/kg) daily for 18 days. Orthotopic colon tumor growth and metastasis to lungs were assessed by in vivo bioluminescence imaging. Results showed that tricin suppressed Colon-Luc cells motility and downregulated phosphorylated Akt, Erk1/2 and NF-κB expressions of human colon cancer HT-29 cells. While tricin treatment suppressed tumor growth and lung metastasis as well as altered the populations of myeloid-derived suppressor cells and regulatory T cells in spleens. In summary, the tumor microenvironment modulatory and anti-metastatic effects of tricin in colon cancer mouse model were shown for the first time, suggesting the potential development of tricin-containing food supplements for CRC patients.

In vivo imaging using a VEGF-based near-infrared fluorescent probe for early cancer diagnosis in the AOM-treated mouse model

2009 ◽  
Author(s):  
Amy M. Winkler ◽  
Photini F. S. Rice ◽  
Jan Weichsel ◽  
Marina V. Backer ◽  
Joseph M. Backer ◽  
...  
Keyword(s):  
Mouse Model ◽  
Fluorescent Probe ◽  
Cancer Diagnosis ◽  
In Vivo Imaging ◽  
Near Infrared ◽  
Early Cancer ◽  
Treated Mouse ◽  
Early Cancer Diagnosis
Sign in / Sign up

Export Citation Format

Share Document