Multimodal fiber-probe spectroscopy as a clinical tool for diagnosing and classifying biological tissues

2017 ◽  
Author(s):  
Riccardo Cicchi ◽  
Suresh Anand ◽  
Riccardo Fantechi ◽  
Flavio Giordano ◽  
Mauro Gacci ◽  
...  
Keyword(s):  
Biological Tissues ◽  
Clinical Tool ◽  
Fiber Probe ◽  
Probe Spectroscopy

scholarly journals Multimodal fiber-probe spectroscopy allows detecting epileptogenic focal cortical dysplasia in children

2017 ◽  
Vol 10 (6-7) ◽  
pp. 896-904 ◽  
Author(s):  
Suresh Anand ◽  
Riccardo Cicchi ◽  
Flavio Giordano ◽  
Valerio Conti ◽  
Anna Maria Buccoliero ◽  
...  
Keyword(s):  
Focal Cortical Dysplasia ◽  
Cortical Dysplasia ◽  
Fiber Probe ◽  
Probe Spectroscopy

Multimodal fiber-probe spectroscopy for the diagnostics and classification of bladder tumors

2017 ◽  
Author(s):  
Suresh Anand ◽  
Riccardo Cicchi ◽  
Riccardo Fantechi ◽  
Mauro Gacci ◽  
Gabriella Nesi ◽  
...  
Keyword(s):  
Bladder Tumors ◽  
Fiber Probe ◽  
Probe Spectroscopy

Single Optical Fiber Probe Spectroscopy for Detection of Dysplastic Tissues

2014 ◽  
pp. 349-354
Author(s):  
Murat Canpolat ◽  
Tuba Denkçeken ◽  
Ayşe Akman-Karakaş ◽  
Erkan Alpsoy ◽  
Recai Tuncer ◽  
...  
Keyword(s):  
Optical Fiber ◽  
Fiber Probe ◽  
Optical Fiber Probe ◽  
Probe Spectroscopy

scholarly journals Optical fiber probe spectroscopy for laparoscopic monitoring of tissue oxygenation during esophagectomies

2010 ◽  
Vol 15 (6) ◽  
pp. 061712 ◽  
Author(s):  
Daniel S. Gareau ◽  
Frederic Truffer ◽  
Kyle Perry ◽  
Thai Pham ◽  
C. Kristian Enestvedt ◽  
...  
Keyword(s):  
Optical Fiber ◽  
Tissue Oxygenation ◽  
Fiber Probe ◽  
Optical Fiber Probe ◽  
Probe Spectroscopy

scholarly journals Errata: Optical fiber probe spectroscopy for laparoscopic monitoring of tissue oxygenation during esophagectomies

2011 ◽  
Vol 16 (3) ◽  
pp. 039801
Author(s):  
Daniel S. Gareau ◽  
Frederic Truffer ◽  
Kyle A. Perry ◽  
Thai H. Pham ◽  
C. Kristian Enestvedt ◽  
...  
Keyword(s):  
Optical Fiber ◽  
Tissue Oxygenation ◽  
Fiber Probe ◽  
Optical Fiber Probe ◽  
Probe Spectroscopy

scholarly journals An Analysis of Open-Ended Coaxial Probe Sensitivity to Heterogeneous Media

Sensors ◽  
2020 ◽  
Vol 20 (18) ◽  
pp. 5372
Author(s):  
Christopher L. Brace ◽  
Sevde Etoz
Keyword(s):  
Heterogeneous Media ◽  
Effective Permittivity ◽  
Three Dimensional ◽  
Biological Tissues ◽  
Field Sensitivity ◽  
Tissue Interface ◽  
Probe Spectroscopy ◽  
Multiple Metrics ◽  
Dimensional Assessment ◽  
Coaxial Probe

Open-ended coaxial probe spectroscopy is commonly used to determine the dielectric permittivity of biological tissues. However, heterogeneities in the probe sensing region can limit measurement precision and reproducibility. This study presents an analysis of the coaxial probe sensing region to elucidate the effects of heterogeneities on measured permittivity. Coaxial probe spectroscopy at 0.5–20 GHz was numerically simulated while a homogenous background was perturbed with a small inclusion of contrasting permittivity. Shifts in the measured effective permittivity provided a three-dimensional assessment of the probe sensitivity field. Sensitivity was well-approximated by the square of the electric field for each analyzed probe. Smaller probes were more sensitive to heterogeneities throughout their sensing region, but were less sensitive to spectral effects compared to larger probes. The probe sensing diameter was less than 0.5 mm in all directions by multiple metrics. Therefore, small heterogeneities may substantially impact permittivity measurement in biological tissues if located near the probe-tissue interface.

Multimodal fiber probe spectroscopy for tissue diagnostics applications: a combined Raman-fluorescence approach

2014 ◽  
Author(s):  
Riccardo Cicchi ◽  
Suresh Anand ◽  
Susanna Rossari ◽  
Alessandro Sturiale ◽  
Flavio Giordano ◽  
...  
Keyword(s):  
Fiber Probe ◽  
Probe Spectroscopy ◽  
Tissue Diagnostics

Three-Dimensional Visualization of the T-System of Frog Muscle Using High Voltage Electron Microscopy and a Lanthanum Stain

1977 ◽  
Vol 35 ◽  
pp. 570-571 ◽  
Author(s):  
Lee D. Peachey ◽  
Clara Franzini-Armstrong
Keyword(s):  
Electron Microscopy ◽  
High Voltage ◽  
Three Dimensional ◽  
Biological Tissues ◽  
High Voltage Electron Microscopy ◽  
Transverse Tubular System ◽  
Peroxidase Reaction ◽  
Voltage Electron ◽  
High Voltage Electron ◽  
T System

The effective study of biological tissues in thick slices of embedded material by high voltage electron microscopy (HVEM) requires highly selective staining of those structures to be visualized so that they are not hidden or obscured by other structures in the image. A tilt pair of micrographs with subsequent stereoscopic viewing can be an important aid in three-dimensional visualization of these images, once an appropriate stain has been found. The peroxidase reaction has been used for this purpose in visualizing the T-system (transverse tubular system) of frog skeletal muscle by HVEM (1). We have found infiltration with lanthanum hydroxide to be particularly useful for three-dimensional visualization of certain aspects of the structure of the T- system in skeletal muscles of the frog. Specifically, lanthanum more completely fills the lumen of the tubules and is denser than the peroxidase reaction product.

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