Ultrasensitive detection of phenolic antioxidants by surface enhanced Raman spectroscopy

Author(s):  
Nancy Ornelas-Soto ◽  
Iris A. Aguilar-Hernández ◽  
Nils Kristian Afseth ◽  
Tzarara López-Luke ◽  
Flavio Contreras-Torres ◽  
...  
Author(s):  
Anil K. Kodali ◽  
Rohit Bhargava

This article describes the use of nanostructured probes to enhance optical and vibrational spectroscopic imaging for biomedical applications. Engineered probes and surfaces are promising tools for enhancing signals for ultrasensitive detection of diseases like carcinoma. Two methods of interest are surface-enhanced infrared absorption (SEIRA) spectroscopy and surface-enhanced Raman spectroscopy (SERS) for IR and Raman modalities, respectively. SERS and SEIRA can be broadly categorized under a common modality termed surface-enhanced vibrational spectroscopy. This article first reviews various breakthrough findings reported in SERS and SEIRA, along with different types ofsubstrates and contrast agents used in realizing the enhancement and theories proposed to explain these findings. It then considers the configurations of nano-LAMPs and presents example results demonstrating their optical resonances and tunability. Finally, it evaluates a few techniques for fabricating multilayered nanoparticles and highlights some issues with respect to fabrication.


RSC Advances ◽  
2013 ◽  
Vol 3 (13) ◽  
pp. 4221 ◽  
Author(s):  
Soumik Siddhanta ◽  
Dhanasekaran Karthigeyan ◽  
Partha P. Kundu ◽  
Tapas K. Kundu ◽  
Chandrabhas Narayana

2014 ◽  
Vol 16 (28) ◽  
pp. 14706-14712 ◽  
Author(s):  
Xuan He ◽  
Hui Wang ◽  
Zhongbo Li ◽  
Dong Chen ◽  
Qi Zhang

Low-cost SERS sensors were fabricated by 4-ATP-functionalized ZnO–Ag hybrid substrates for TNT detection with high sensitivity, selectivity and reproducibility.


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