Wide-field surface-enhanced CARS microscopy of cells (Conference Presentation)

2017 ◽  
Author(s):  
Alexander Fast ◽  
John T. Kenison ◽  
Eric O. Potma
Keyword(s):  
Wide Field ◽  
Surface Enhanced ◽  
Cars Microscopy

scholarly journals Selective imaging of saturated and unsaturated lipids by wide-field CARS-microscopy

2008 ◽  
Vol 16 (4) ◽  
pp. 2699 ◽  
Author(s):  
Christoph Heinrich ◽  
Alexander Hofer ◽  
Andreas Ritsch ◽  
Christian Ciardi ◽  
Stefan Bernet ◽  
...  
Keyword(s):  
Wide Field ◽  
Unsaturated Lipids ◽  
Cars Microscopy

Plasmonic patterned wide-field gap mode mechanism for surface enhanced Raman imaging

2016 ◽  
Vol 109 (26) ◽  
pp. 261904
Author(s):  
Houkai Chen ◽  
Luping Du ◽  
Xiaojing Wu ◽  
Siwei Zhu ◽  
Yong Yang ◽  
...  
Keyword(s):  
Raman Imaging ◽  
Wide Field ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Gap Mode

scholarly journals Wide-field Surface-Enhanced Coherent Anti-Stokes Raman Scattering Microscopy

2021 ◽  
Author(s):  
Cheng Zong ◽  
Ran Cheng ◽  
Fukai Chen ◽  
Peng Lin ◽  
Meng Zhang ◽  
...  
Keyword(s):  
Raman Scattering ◽  
Large Scale ◽  
Time Lapse ◽  
Live Cells ◽  
Large Field ◽  
Wide Field ◽  
Label Free ◽  
Label Free Detection ◽  
Surface Enhanced ◽  
Anti Stokes

Surface-enhanced Raman scattering (SERS) spectroscopy has been used extensively to study biology, chemistry, and materials. However, a point-by-point SERS mapping is time-consuming, taking minutes to hours for large-scale imaging. Here, we report a wide-field surface-enhanced coherent anti-Stokes Raman scattering (WISE-CARS) microscopy for monitoring nanotags in live cells and label-free detection of metabolic molecules. The WISE-CARS microscope achieves an imaging speed as fast as 120 frames per second for a large field of view of 130 microns X 130 microns. By spectral focusing of femtosecond lasers, a hyperspectral WISE-CARS stack of 120 frames can be acquired with a spectral resolution of 10 cm-1, where over 1 million Raman spectra are parallelly recorded within 0.5 seconds. As applications, we demonstrate time-lapse, 3D WISE-CARS imaging of nanotags in live cells as well as label-free detection of adenine released from S. aureus.

WIDE-FIELD CARS-MICROSCOPY

2008 ◽  
Author(s):  
CHRISTOPH HEINRICH ◽  
ALEXANDER HOFER ◽  
STEFAN BERNET ◽  
MONIKA RITSCH-MARTE
Keyword(s):  
Wide Field ◽  
Cars Microscopy

scholarly journals On illumination schemes for wide-field CARS microscopy

2009 ◽  
Vol 17 (9) ◽  
pp. 7339 ◽  
Author(s):  
I. Toytman ◽  
D. Simanovskii ◽  
D. Palanker
Keyword(s):  
Wide Field ◽  
Cars Microscopy

Wide-field CARS-Microscopy

2007 ◽  
Vol 9 (4) ◽  
pp. 52-54
Author(s):  
M.A.M. Ritsch-Marte ◽  
S. Bernet ◽  
C. Heinrich
Keyword(s):  
Wide Field ◽  
Cars Microscopy

scholarly journals iSERS microscopy guided by wide field immunofluorescence: analysis of HER2 expression on normal and breast cancer FFPE tissue sections

The Analyst ◽  
2016 ◽  
Vol 141 (17) ◽  
pp. 5113-5119 ◽  
Author(s):  
Xin-Ping Wang ◽  
Yuying Zhang ◽  
Matthias König ◽  
Evanthia Papadopoulou ◽  
Bernd Walkenfort ◽  
...  
Keyword(s):  
Imaging Technique ◽  
Cancer Diagnostics ◽  
Ffpe Tissue ◽  
Wide Field ◽  
Her2 Expression ◽  
Immunofluorescence Analysis ◽  
Tissue Sections ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Enhanced Raman Scattering

Surface-enhanced Raman scattering (SERS) microscopy is an emerging imaging technique for tissue-based cancer diagnostics.

scholarly journals Solid state lasers for wide-field CARS microscopy

2009 ◽  
Author(s):  
D. Simanovskii ◽  
I. Toytman ◽  
D. Palanker
Keyword(s):  
Solid State ◽  
Wide Field ◽  
Solid State Lasers ◽  
Cars Microscopy
Sign in / Sign up

Export Citation Format

Share Document