Conducting polymer scaffolds for electrical control of cellular functions (Conference Presentation)

Author(s):  
Sahika Inal ◽  
Alwin M. Wan ◽  
Tiffany V. Williams ◽  
Emmanuel P. Giannelis ◽  
Claudia Fischbach-Teschl ◽  
...  
2015 ◽  
Vol 3 (25) ◽  
pp. 5040-5048 ◽  
Author(s):  
Alwin Ming-Doug Wan ◽  
Sahika Inal ◽  
Tiffany Williams ◽  
Karin Wang ◽  
Pierre Leleux ◽  
...  

Ice-templating of the conducting polymer PEDOT:PSS yields 3D tissue-mimicking scaffolds that can electrically control protein conformation and various cell functions.


2017 ◽  
Vol 1 (6) ◽  
Author(s):  
Sahika Inal ◽  
Adel Hama ◽  
Magali Ferro ◽  
Charalampos Pitsalidis ◽  
Julie Oziat ◽  
...  

2009 ◽  
pp. 5278 ◽  
Author(s):  
Alwin M. D. Wan ◽  
Daniel J. Brooks ◽  
Abdurrahman Gumus ◽  
Claudia Fischbach ◽  
George G. Malliaras

2002 ◽  
Vol 14 (23) ◽  
pp. 1644-1647 ◽  
Author(s):  
Shunichi Uchiyama ◽  
Masanao Kobayashi ◽  
Yasushi Hasebe

ACS Omega ◽  
2018 ◽  
Vol 3 (7) ◽  
pp. 7424-7431 ◽  
Author(s):  
Isabel del Agua ◽  
Sara Marina ◽  
Charalampos Pitsalidis ◽  
Daniele Mantione ◽  
Magali Ferro ◽  
...  

2017 ◽  
Vol 1 (6) ◽  
pp. 1700052 ◽  
Author(s):  
Sahika Inal ◽  
Adel Hama ◽  
Magali Ferro ◽  
Charalampos Pitsalidis ◽  
Julie Oziat ◽  
...  

2008 ◽  
Vol 76 (8) ◽  
pp. 532-534 ◽  
Author(s):  
Matsuhiko NISHIZAWA ◽  
Takahiro KITAZUME ◽  
Hirokazu KAJI

Author(s):  
Robert M. Glaeser ◽  
Thea B. Scott

The carbon-replica technique can be used to obtain information about cell-surface structure that cannot ordinarily be obtained by thin-section techniques. Mammalian erythrocytes have been studied by the replica technique and they appear to be characterized by a pebbly or “plaqued“ surface texture. The characteristic “particle” diameter is about 200 Å to 400 Å. We have now extended our observations on cell-surface structure to chicken and frog erythrocytes, which possess a broad range of cellular functions, and to normal rat lymphocytes and mouse ascites tumor cells, which are capable of cell division. In these experiments fresh cells were washed in Eagle's Minimum Essential Medium Salt Solution (for suspension cultures) and one volume of a 10% cell suspension was added to one volume of 2% OsO4 or 5% gluteraldehyde in 0.067 M phosphate buffer, pH 7.3. Carbon replicas were obtained by a technique similar to that employed by Glaeser et al. Figure 1 shows an electron micrograph of a carbon replica made from a chicken erythrocyte, and Figure 2 shows an enlarged portion of the same cell.


Author(s):  
D. L. Taylor

Cells function through the complex temporal and spatial interplay of ions, metabolites, macromolecules and macromolecular assemblies. Biochemical approaches allow the investigator to define the components and the solution chemical reactions that might be involved in cellular functions. Static structural methods can yield information concerning the 2- and 3-D organization of known and unknown cellular constituents. Genetic and molecular techniques are powerful approaches that can alter specific functions through the manipulation of gene products and thus identify necessary components and sequences of molecular events. However, full knowledge of the mechanism of particular cell functions will require direct measurement of the interplay of cellular constituents. Therefore, there has been a need to develop methods that can yield chemical and molecular information in time and space in living cells, while allowing the integration of information from biochemical, molecular and genetic approaches at the cellular level.


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