Quantitative phase imaging by wide field lensless digital holographic microscope

2015 ◽  
Author(s):  
A. Adinda-Ougba ◽  
N. Koukourakis ◽  
A. Essaidi ◽  
N. C. Ger­hardt ◽  
M. R. Hofmann
Keyword(s):  
Wide Field ◽  
Phase Imaging ◽  
Quantitative Phase Imaging ◽  
Quantitative Phase

scholarly journals Adaptive dynamic range shift (ADRIFT) quantitative phase imaging

2021 ◽  
Vol 10 (1) ◽  
Author(s):  
Keiichiro Toda ◽  
Miu Tamamitsu ◽  
Takuro Ideguchi
Keyword(s):  
Dynamic Range ◽  
Range Shift ◽  
Wide Field ◽  
Phase Imaging ◽  
Label Free ◽  
Quantitative Phase Imaging ◽  
Mid Infrared ◽  
Quantitative Phase ◽  
Adaptive Dynamic ◽  
Sensitivity Improvement

AbstractQuantitative phase imaging (QPI) with its high-contrast images of optical phase delay (OPD) maps is often used for label-free single-cell analysis. Contrary to other imaging methods, sensitivity improvement has not been intensively explored because conventional QPI is sensitive enough to observe the surface roughness of a substrate that restricts the minimum measurable OPD. However, emerging QPI techniques that utilize, for example, differential image analysis of consecutive temporal frames, such as mid-infrared photothermal QPI, mitigate the minimum OPD limit by decoupling the static OPD contribution and allow measurement of much smaller OPDs. Here, we propose and demonstrate supersensitive QPI with an expanded dynamic range. It is enabled by adaptive dynamic range shift through a combination of wavefront shaping and dark-field QPI techniques. As a proof-of-concept demonstration, we show dynamic range expansion (sensitivity improvement) of QPI by a factor of 6.6 and its utility in improving the sensitivity of mid-infrared photothermal QPI. This technique can also be applied for wide-field scattering imaging of dynamically changing nanoscale objects inside and outside a biological cell without losing global cellular morphological image information.

Wavelength-scanning lensfree on-chip microscopy for wide-field pixel-super-resolved quantitative phase imaging

2021 ◽  
Author(s):  
Xuejuan Wu ◽  
Jiasong Sun ◽  
Jialin Zhang ◽  
Linpeng Lu ◽  
Rong Chen ◽  
...  
Keyword(s):  
Wide Field ◽  
Phase Imaging ◽  
Quantitative Phase Imaging ◽  
Quantitative Phase ◽  
Wavelength Scanning ◽  
On Chip

scholarly journals Nanoscale topography and spatial light modulator characterization using wide-field quantitative phase imaging

2014 ◽  
Vol 22 (3) ◽  
pp. 3432 ◽  
Author(s):  
Gannavarpu Rajshekhar ◽  
Basanta Bhaduri ◽  
Chris Edwards ◽  
Renjie Zhou ◽  
Lynford L. Goddard ◽  
...  
Keyword(s):  
Spatial Light Modulator ◽  
Wide Field ◽  
Phase Imaging ◽  
Quantitative Phase Imaging ◽  
Light Modulator ◽  
Quantitative Phase ◽  
Nanoscale Topography

scholarly journals Quantitative phase imaging by wide-field interferometry with variable shearing distance uncoupled from the off-axis angle

2020 ◽  
Vol 28 (4) ◽  
pp. 5617 ◽  
Author(s):  
Rongli Guo ◽  
Simcha K. Mirsky ◽  
Itay Barnea ◽  
Matan Dudaie ◽  
Natan T. Shaked
Keyword(s):  
Wide Field ◽  
Phase Imaging ◽  
Quantitative Phase Imaging ◽  
Quantitative Phase

scholarly journals Simultaneous measurement of neurite and neural body mass accumulation via quantitative phase imaging

The Analyst ◽  
2021 ◽  
Author(s):  
Soorya Pradeep ◽  
Tasmia Tasnim ◽  
Huanan Zhang ◽  
Thomas A. Zangle
Keyword(s):  
Body Mass ◽  
Biomass Production ◽  
Simultaneous Measurement ◽  
Neural Differentiation ◽  
Phase Imaging ◽  
Quantitative Phase Imaging ◽  
Quantitative Phase ◽  
Mass Accumulation

Quantitative phase imaging (QPI) used to quantify the mass of soma (cell bodies) and neurites as well as the rates of biomass production due to neurite maturation and formation during neural differentiation.

scholarly journals High-speed line-field confocal holographic microscope for quantitative phase imaging

2016 ◽  
Vol 24 (9) ◽  
pp. 9251 ◽  
Author(s):  
Changgeng Liu ◽  
Sebastian Knitter ◽  
Zhilong Cong ◽  
Ikbal Sencan ◽  
Hui Cao ◽  
...  
Keyword(s):  
High Speed ◽  
Phase Imaging ◽  
Quantitative Phase Imaging ◽  
Line Field ◽  
Quantitative Phase
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