Laser-induced fluorescence spectroscopy at endoscopy: tissue optics, Monte Carlo modeling, and in vivo measurements

1995 ◽  
Vol 34 (11) ◽  
pp. 3334 ◽  
Author(s):  
Jianan Y. Qu
Keyword(s):  
Monte Carlo ◽  
Fluorescence Spectroscopy ◽  
Laser Induced Fluorescence ◽  
Tissue Optics ◽  
Monte Carlo Modeling ◽  
In Vivo Measurements

In vivo real-time assessment of colorectal polyp histology using an optical biopsy forceps system based on laser-induced fluorescence spectroscopy

Endoscopy ◽  
2016 ◽  
Vol 48 (06) ◽  
pp. 557-562 ◽  
Author(s):  
Timo Rath ◽  
Gian Tontini ◽  
Michael Vieth ◽  
Andreas Nägel ◽  
Markus Neurath ◽  
...  
Keyword(s):  
Fluorescence Spectroscopy ◽  
Real Time ◽  
Colorectal Polyp ◽  
Laser Induced Fluorescence ◽  
Optical Biopsy ◽  
Biopsy Forceps ◽  
Time Assessment

scholarly journals Laser-Induced Fluorescence Spectroscopy in the Diagnosis of Tissue Hypoxia (Review)

2019 ◽  
Vol 15 (6) ◽  
pp. 50-61
Author(s):  
Anastasiya S. Babkina
Keyword(s):  
Fluorescence Spectroscopy ◽  
Clinical Medicine ◽  
Laser Induced Fluorescence ◽  
Tissue Hypoxia ◽  
Endogenous Factors ◽  
Tissue Ischemia ◽  
Promising Area ◽  
Reduced Nicotinamide Adenine Dinucleotide ◽  
The Impact

The aim of review is to discuss the results of studies on diagnosis of tissue hypoxia by laser-induced spectroscopy, as well as to identify promising trends and prospects of this technique for its further application in experimental and clinical medicine.The review presents the findings of studies of the fluorescence intensity of endogenous fluorophore molecules (reduced nicotinamide adenine dinucleotide, oxidized flavin adenine dinucleotide) as markers of ischemic injury of internal organs (brain, heart, liver, kidneys, etc.). The principles of fluorescence laser-induced spectroscopy in vivo are discussed. The historical aspects of the subject are also covered. The results of the use of the technique in experimental and clinical studies of tissue hypoxia and ischemia are shown. Difficulties in interpreting the intensity values of autofluorescent signal of the studied molecules are revealed. It was noted that the tissue autofluorescence in a long-term anoxia remains unknown, and there are no structured ideas about the impact of exogenous and endogenous factors on autofluorescence intensity.In conclusion, the use of laser-induced fluorescence spectroscopy to diagnose tissue ischemia is a promising area of experimental and clinical medicine, which still has various unresolved issues, despite a large number of studies in this domain.

Monte Carlo modeling and in-vivo imaging at the Heidelberg Ion Beam Therapy Center

2011 ◽  
Author(s):  
Katia Parodi ◽  
Julia Bauer ◽  
Christopher Kurz ◽  
Andrea Mairani ◽  
Florian Sommerer ◽  
...  
Keyword(s):  
Monte Carlo ◽  
In Vivo Imaging ◽  
Ion Beam ◽  
Monte Carlo Modeling ◽  
Ion Beam Therapy ◽  
Therapy Center

Laser-induced fluorescence spectroscopy for in vivo diagnosis of non-melanoma skin cancers

2002 ◽  
Vol 31 (5) ◽  
pp. 367-373 ◽  
Author(s):  
Masoud Panjehpour ◽  
Clark E. Julius ◽  
Mary N. Phan ◽  
Tuan Vo-Dinh ◽  
Suzanne Overholt
Keyword(s):  
Fluorescence Spectroscopy ◽  
Laser Induced Fluorescence ◽  
Skin Cancers ◽  
In Vivo Diagnosis ◽  
Melanoma Skin

Coupling in vivo measurements and Monte-Carlo simulations to assess organ specific activity

2013 ◽  
Vol 51-52 ◽  
pp. 55-61
Author(s):  
J. Farah ◽  
O. Marzocchi ◽  
D. Leone ◽  
B. Breustedt ◽  
D. Franck ◽  
...  
Keyword(s):  
Monte Carlo ◽  
Monte Carlo Simulations ◽  
Specific Activity ◽  
In Vivo Measurements ◽  
Organ Specific
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