DTI - DKI fitting: a graphical toolbox for estimation and visualization of diffusion tensor and diffusion kurtosis imaging

2015 ◽  
Author(s):  
Rajikha Raja ◽  
Neelam Sinha ◽  
Jitender Saini
Keyword(s):  
Diffusion Tensor ◽  
Diffusion Kurtosis Imaging ◽  
Diffusion Kurtosis ◽  
And Diffusion

Assessment of tissue heterogeneity using diffusion tensor and diffusion kurtosis imaging for grading gliomas

2016 ◽  
Vol 58 (12) ◽  
pp. 1217-1231 ◽  
Author(s):  
Rajikha Raja ◽  
Neelam Sinha ◽  
Jitender Saini ◽  
Anita Mahadevan ◽  
KVL Narasinga Rao ◽  
...  
Keyword(s):  
Diffusion Tensor ◽  
Diffusion Kurtosis Imaging ◽  
Tissue Heterogeneity ◽  
Diffusion Kurtosis ◽  
And Diffusion

The diagnostic value of T2 map, diffusion tensor imaging, and diffusion kurtosis imaging in differentiating dermatomyositis from muscular dystrophy

2021 ◽  
pp. 028418512199900
Author(s):  
Jun Ran ◽  
Bin Dai ◽  
Chanyuan Liu ◽  
Huayue Zhang ◽  
Yitong Li ◽  
...  
Keyword(s):  
Diffusion Tensor Imaging ◽  
Muscular Dystrophy ◽  
Diffusion Tensor ◽  
Mean Diffusivity ◽  
Diagnostic Value ◽  
Thigh Muscle ◽  
Diffusion Kurtosis Imaging ◽  
T2 Map ◽  
Diffusion Kurtosis ◽  
And Diffusion

Background Dermatomyositis (DM) and muscular dystrophy are clinically difficult to differentiate. Purpose To confirm the feasibility and assess the accuracy of conventional magnetic resonance imaging (MRI), T2 map, diffusion tensor imaging (DTI), and diffusion kurtosis imaging (DKI) in the differentiation of DM from muscular dystrophy. Material and Methods Forty-two patients with DM proven by diagnostic criteria were enrolled in the study along with 23 patients with muscular dystrophy. Conventional MR, T2 map, DTI, and DKI images were obtained in the thigh musculature for all patients. Intramuscular T2 value, apparent diffusion coefficient (ADC), fractional anisotropy (FA), mean diffusivity (MD), and mean kurtosis (MK) values were compared between the patients with DM and muscular dystrophy. Student’s t-tests and receiver operating characteristic (ROC) curve analyses were performed for all parameters. P values < 0.05 were considered statistically significant. Results The intramuscular T2, ADC, FA, MD, and MK values within muscles were statistically significantly different between the DM and muscular dystrophy groups ( P<0.01). The MK value was statistically significantly different between the groups in comparison with T2 and FA value. As a supplement to conventional MRI, the parameters of MD and MK differentiated DM and muscular dystrophy may be valuable. The optimal cut-off value of ADC and MD values (with respective AUC, sensitivity, and specificity) between DM and muscular dystrophy were 1.698 ×10−3mm2/s (0.723, 54.1%, and 78.1%) and 1.80 ×10−3mm2/s (61.9% and 70.2%), respectively. Conclusion Thigh muscle ADC and MD parameters may be useful in differentiating patients with DM from those with muscular dystrophy.

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