A novel framework for the temporal analysis of bone mineral density in metastatic lesions using CT images of the femur

2015 ◽  
Author(s):  
Tom H. Knoop ◽  
Loes C. Derikx ◽  
Nico Verdonschot ◽  
Cornelis H. Slump
Keyword(s):  
Bone Mineral Density ◽  
Bone Mineral ◽  
Temporal Analysis ◽  
Ct Images ◽  
Mineral Density ◽  
Metastatic Lesions

scholarly journals Bone mineral density (BMD) and computer tomographic measurements of the equine proximal phalanx in correlation with breaking strength

2013 ◽  
Vol 16 (1) ◽  
pp. 3-8 ◽  
Author(s):  
P. Tóth ◽  
C. Horváth ◽  
V. Ferencz ◽  
B. Tóth ◽  
A. Váradi ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Fracture Risk ◽  
Bone Mineral ◽  
Risk Model ◽  
Breaking Strength ◽  
Proximal Phalanx ◽  
Ct Images ◽  
Mineral Density

Abstract Despite the fact that bone mineral density (BMD) is an important fracture risk predictor in human medicine, studies in equine orthopedic research are still lacking. We hypothesized that BMD correlates with bone failure and fatigue fractures of this bone. Thus, the objectives of this study were to measure the structural and mechanical properties of the proximal phalanx with dual energy X-ray absorptiometry (DXA), to correlate the data obtained from DXA and computer tomography (CT) measurements to those obtained by loading pressure examination and to establish representative region of interest (ROI) for in vitro BMD measurements of the equine proximal phalanx for predicting bone failure force. DXA was used to measure the whole bone BMD and additional three ROI sites in 14 equine proximal phalanges. Following evaluation of the bone density, whole bone, cortical width and area in the mid-diaphyseal plane were measured on CT images. Bones were broken using a manually controlled universal bone crusher to measure bone failure force and reevaluated for the site of fractures on follow-up CT images. Compressive load was applied at a constant displacement rate of 2 mm/min until failure, defined as the first clear drop in the load measurement. The lowest BMD was measured at the trabecular region (mean ± SD: 1.52 ± 0.12 g/cm2; median: 1.48 g/cm2; range: 1.38-1.83 g/cm2). There was a significant positive linear correlation between trabelcular BMD and the breaking strength (P=0.023, r=0.62). The trabecular region of the proximal phalanx appears to be the only significant indicator of failure of strength in vitro. This finding should be reassessed to further reveal the prognostic value of trabecular BMD in an in vivo fracture risk model.

Osteoporosis Screening Using Areal Bone Mineral Density Estimation from Diagnostic CT Images

2012 ◽  
Vol 19 (10) ◽  
pp. 1273-1282 ◽  
Author(s):  
Wei-Liang Tay ◽  
Chee-Kong Chui ◽  
Sim-Heng Ong ◽  
Alvin Choong-Meng Ng
Keyword(s):  
Bone Mineral Density ◽  
Density Estimation ◽  
Bone Mineral ◽  
Ct Images ◽  
Areal Bone Mineral Density ◽  
Mineral Density ◽  
Osteoporosis Screening ◽  
Diagnostic Ct

scholarly journals Bone marrow lesions in the knee diagnosed in MR images are associated with locally increased bone mineral density measured on CT images

2012 ◽  
Vol 20 ◽  
pp. S209-S210 ◽  
Author(s):  
T. Lowitz ◽  
O. Museyko ◽  
L. Laouisset ◽  
J.-D. Laredo ◽  
V.D. Bousson ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Bone Marrow ◽  
Bone Mineral ◽  
Ct Images ◽  
Mr Images ◽  
Mineral Density ◽  
Bone Marrow Lesions

scholarly journals Investigation on the contour and bone mineral density of the distal tibial cutting surface used for total ankle arthroplasty

2021 ◽  
Vol 29 (2) ◽  
pp. 230949902110280
Author(s):  
Dahang Zhao ◽  
Gonghao Zhang ◽  
Dichao Huang ◽  
Jian Yu ◽  
Kan Wang ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Cortical Bone ◽  
Bone Mineral ◽  
Ct Images ◽  
Total Ankle Arthroplasty ◽  
Tibial Tubercle ◽  
Mineral Density ◽  
Ankle Arthroplasty ◽  
Cutting Surface ◽  
Value Measurement

Purpose: This study was designed to investigate (1) the contour of the distal tibial cutting surface, and (2) the bone mineral density (BMD) of the distal tibial cutting surface used during total ankle arthroplasty (TAA). Methods: Eight-four distal tibial models were created using foot and ankle computerized tomographic (CT) images taken from normal people. The distal tibial cutting surface for TAA was determined to be 10 mm proximal to the tibial plafond. The bony contour and BMD values were determined from the CT image at that level. A bounding box was made on the contour and the width and length of the contour was measured. Regional BMD was evaluated by Hounsfield units (HU) value measurement, with 7 regions of interest (ROI) on 8 different directions for all the 84 CT images. Two different observers made independent measurements and mean HU values for all the 56 ROIs were calculated. Results: Great variations were found among the contours of the cutting surface especially in term of the shape of the anterior and posterior tibial tubercle, and the fibular notch. These variations could be grouped into six categories. For the BMD of the cutting surface, the medial border of the cutting surface did not included cortical bone. The HU value of seven ROIs, which included cortical bone, were significantly greater than all the other ROIs. Few statistical differences were found by multiple comparisons among HU value of all the 49 ROIs without cortex. Conclusions: Great variability existed in the shape and the BMD of the distal tibial cutting surface.

scholarly journals Estimation of bone mineral density in children from diagnostic CT images: A comparison of methods with and without an internal calibration standard

Bone ◽  
2011 ◽  
Vol 48 (5) ◽  
pp. 1087-1094 ◽  
Author(s):  
Alexander H. Habashy ◽  
Xiaowei Yan ◽  
J. Keenan Brown ◽  
Xiaoping Xiong ◽  
Sue C. Kaste
Keyword(s):  
Bone Mineral Density ◽  
Bone Mineral ◽  
Ct Images ◽  
Comparison Of Methods ◽  
Calibration Standard ◽  
Mineral Density ◽  
Internal Calibration ◽  
Diagnostic Ct
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