Live dynamic imaging and analysis of developmental cardiac defects in mouse models with optical coherence tomography

2015 ◽  
Author(s):  
Andrew L. Lopez ◽  
Shang Wang ◽  
Monica Garcia ◽  
Christian Valladolid ◽  
Kirill V. Larin ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Mouse Models ◽  
Dynamic Imaging ◽  
Optical Coherence ◽  
Cardiac Defects

Dynamic imaging of penetration and decontamination after chemical eye burn using optical coherence tomography

2007 ◽  
Author(s):  
Felix Spöler ◽  
Michael Först ◽  
Heinrich Kurz ◽  
Markus Frentz ◽  
Norbert F. Schrage
Keyword(s):  
Optical Coherence Tomography ◽  
Dynamic Imaging ◽  
Optical Coherence

Anatomic optical coherence tomography for dynamic imaging of the upper airway

2017 ◽  
Author(s):  
Ruofei Bu ◽  
Santosh Balakrishnan ◽  
Nicusor Iftimia ◽  
Hillel Price ◽  
Carlton Zdanski ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Upper Airway ◽  
Dynamic Imaging ◽  
Optical Coherence

Static and dynamic imaging of alveoli using optical coherence tomography needle probes

2012 ◽  
Vol 113 (6) ◽  
pp. 967-974 ◽  
Author(s):  
Robert A. McLaughlin ◽  
Xiaojie Yang ◽  
Bryden C. Quirk ◽  
Dirk Lorenser ◽  
Rodney W. Kirk ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Three Dimensional ◽  
Dynamic Imaging ◽  
Hypodermic Needle ◽  
Outer Diameter ◽  
Optical Coherence ◽  
Adult Rats ◽  
Fetal Sheep ◽  
Lung Inflation ◽  
Needle Probe

Imaging of alveoli in situ has for the most part been infeasible due to the high resolution required to discern individual alveoli and limited access to alveoli beneath the lung surface. In this study, we present a novel technique to image alveoli using optical coherence tomography (OCT). We propose the use of OCT needle probes, where the distal imaging probe has been miniaturized and encased within a hypodermic needle (as small as 30-gauge, outer diameter 310 μm), allowing insertion deep within the lung tissue with minimal tissue distortion. Such probes enable imaging at a resolution of ∼12 μm within a three-dimensional cylindrical field of view with diameter ∼1.5 mm centered on the needle tip. The imaging technique is demonstrated on excised lungs from three different species: adult rats, fetal sheep, and adult pigs. OCT needle probes were used to image alveoli, small bronchioles, and blood vessels, and results were matched to histological sections. We also present the first dynamic OCT images acquired with an OCT needle probe, allowing tracking of individual alveoli during simulated cyclical lung inflation and deflation.

scholarly journals Dynamic imaging of accommodation by swept-source anterior segment optical coherence tomography

2015 ◽  
Vol 41 (3) ◽  
pp. 501-510 ◽  
Author(s):  
Alberto Neri ◽  
Marco Ruggeri ◽  
Alessandra Protti ◽  
Rosachiara Leaci ◽  
Stefano A. Gandolfi ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Anterior Segment ◽  
Dynamic Imaging ◽  
Optical Coherence ◽  
Swept Source
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