Apparatus and fast method for cancer cell classification based on high harmonic coherent diffraction imaging in reflection geometry

2014 ◽  
Author(s):  
Michael Zürch ◽  
Stefan Foertsch ◽  
Mark Matzas ◽  
Katharina Pachmann ◽  
Rainer Kuth ◽  
...  
Keyword(s):  
Cancer Cell ◽  
High Harmonic ◽  
Fast Method ◽  
Cell Classification ◽  
Coherent Diffraction Imaging ◽  
Diffraction Imaging ◽  
Reflection Geometry

scholarly journals Cancer cell classification with coherent diffraction imaging using an extreme ultraviolet radiation source

2014 ◽  
Vol 1 (3) ◽  
pp. 031008 ◽  
Author(s):  
Michael Zürch ◽  
Stefan Foertsch ◽  
Mark Matzas ◽  
Katharina Pachmann ◽  
Rainer Kuth ◽  
...  
Keyword(s):  
Ultraviolet Radiation ◽  
Cancer Cell ◽  
Radiation Source ◽  
Extreme Ultraviolet ◽  
Cell Classification ◽  
Coherent Diffraction Imaging ◽  
Diffraction Imaging ◽  
Extreme Ultraviolet Radiation

Ultrahigh 22-nm resolution EUV coherent diffraction imaging using a tabletop 13-nm high harmonic source

2012 ◽  
Author(s):  
Matthew D. Seaberg ◽  
Daniel E. Adams ◽  
Bosheng Zhang ◽  
Dennis F. Gardner ◽  
Margaret M. Murnane ◽  
...  
Keyword(s):  
High Harmonic ◽  
Coherent Diffraction Imaging ◽  
Diffraction Imaging ◽  
Harmonic Source

scholarly journals Oversampling smoothness: an effective algorithm for phase retrieval of noisy diffraction intensities

2013 ◽  
Vol 46 (2) ◽  
pp. 312-318 ◽  
Author(s):  
Jose A. Rodriguez ◽  
Rui Xu ◽  
Chien-Chun Chen ◽  
Yunfei Zou ◽  
Jianwei Miao
Keyword(s):  
Phase Retrieval ◽  
High Harmonic ◽  
Solution Space ◽  
Real Space ◽  
X Ray ◽  
Coherent Diffraction Imaging ◽  
Wide Range ◽  
Diffraction Imaging ◽  
Correlation Information ◽  
Noise Robust

Coherent diffraction imaging (CDI) is high-resolution lensless microscopy that has been applied to image a wide range of specimens using synchrotron radiation, X-ray free-electron lasers, high harmonic generation, soft X-ray lasers and electrons. Despite recent rapid advances, it remains a challenge to reconstruct fine features in weakly scattering objects such as biological specimens from noisy data. Here an effective iterative algorithm, termed oversampling smoothness (OSS), for phase retrieval of noisy diffraction intensities is presented. OSS exploits the correlation information among the pixels or voxels in the region outside of a support in real space. By properly applying spatial frequency filters to the pixels or voxels outside the support at different stages of the iterative process (i.e.a smoothness constraint), OSS finds a balance between the hybrid input–output (HIO) and error reduction (ER) algorithms to search for a global minimum in solution space, while reducing the oscillations in the reconstruction. Both numerical simulations with Poisson noise and experimental data from a biological cell indicate that OSS consistently outperforms the HIO, ER–HIO and noise robust (NR)–HIO algorithms at all noise levels in terms of accuracy and consistency of the reconstructions. It is expected that OSS will find application in the rapidly growing CDI field, as well as other disciplines where phase retrieval from noisy Fourier magnitudes is needed. TheMATLAB(The MathWorks Inc., Natick, MA, USA) source code of the OSS algorithm is freely available from http://www.physics.ucla.edu/research/imaging.

scholarly journals XUV coherent diffraction imaging in reflection geometry with low numerical aperture

2013 ◽  
Vol 21 (18) ◽  
pp. 21131 ◽  
Author(s):  
Michael Zürch ◽  
Christian Kern ◽  
Christian Spielmann
Keyword(s):  
Numerical Aperture ◽  
Coherent Diffraction Imaging ◽  
Diffraction Imaging ◽  
Reflection Geometry

Electrochemically Induced Strain Evolution in Pt–Ni Alloy Nanoparticles Observed by Bragg Coherent Diffraction Imaging

Nano Letters ◽  
2021 ◽  
Author(s):  
Tomoya Kawaguchi ◽  
Vladimir Komanicky ◽  
Vitalii Latyshev ◽  
Wonsuk Cha ◽  
Evan R. Maxey ◽  
...  
Keyword(s):  
Alloy Nanoparticles ◽  
Strain Evolution ◽  
Coherent Diffraction Imaging ◽  
Ni Alloy ◽  
Diffraction Imaging

scholarly journals Complex wavefront sensing based on coherent diffraction imaging using vortex modulation

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Rujia Li ◽  
Liangcai Cao
Keyword(s):  
Phase Retrieval ◽  
Dynamic Range ◽  
A Priori ◽  
Measured Intensity ◽  
Physical Constraints ◽  
Coherent Diffraction Imaging ◽  
Effective Dynamic ◽  
Ill Posed ◽  
Retrieval Problem ◽  
Diffraction Imaging

AbstractPhase retrieval seeks to reconstruct the phase from the measured intensity, which is an ill-posed problem. A phase retrieval problem can be solved with physical constraints by modulating the investigated complex wavefront. Orbital angular momentum has been recently employed as a type of reliable modulation. The topological charge l is robust during propagation when there is atmospheric turbulence. In this work, topological modulation is used to solve the phase retrieval problem. Topological modulation offers an effective dynamic range of intensity constraints for reconstruction. The maximum intensity value of the spectrum is reduced by a factor of 173 under topological modulation when l is 50. The phase is iteratively reconstructed without a priori knowledge. The stagnation problem during the iteration can be avoided using multiple topological modulations.

Experimental demonstration of coupled multi-peak Bragg coherent diffraction imaging with genetic algorithms

2021 ◽  
Vol 103 (21) ◽  
Author(s):  
Matthew J. Wilkin ◽  
Siddharth Maddali ◽  
Stephan O. Hruszkewycz ◽  
Anastasios Pateras ◽  
Richard L. Sandberg ◽  
...  
Keyword(s):  
Genetic Algorithms ◽  
Experimental Demonstration ◽  
Coherent Diffraction Imaging ◽  
Diffraction Imaging

High-resolution multi-planar coherent diffraction imaging with multimode fiber source

2021 ◽  
Vol 140 ◽  
pp. 106530
Author(s):  
Yuanyuan Liu ◽  
Qingwen Liu ◽  
You Li ◽  
Junyong Zhang ◽  
Zuyuan He
Keyword(s):  
High Resolution ◽  
Multimode Fiber ◽  
Coherent Diffraction Imaging ◽  
Diffraction Imaging

Enhanced high-speed coherent diffraction imaging

2011 ◽  
Author(s):  
Jonathan Potier ◽  
Sebastien Fricker ◽  
Mourad Idir
Keyword(s):  
High Speed ◽  
Coherent Diffraction Imaging ◽  
Diffraction Imaging
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