Monitoring the effects of fibrinogen concentration on blood coagulation using quartz crystal microbalance (QCM) and its comparison with thromboelastography

2013 ◽  
Author(s):  
Ramji S. Lakshmanan ◽  
Vitaly Efremov ◽  
Sinéad Cullen ◽  
Barry Byrne ◽  
Anthony J. Killard
Keyword(s):  
Blood Coagulation ◽  
Quartz Crystal Microbalance ◽  
Quartz Crystal ◽  
Fibrinogen Concentration

scholarly journals Blood Coagulation Testing Smartphone Platform Using Quartz Crystal Microbalance Dissipation Method

Sensors ◽  
2018 ◽  
Vol 18 (9) ◽  
pp. 3073 ◽  
Author(s):  
Jia Yao ◽  
Bin Feng ◽  
Zhiqi Zhang ◽  
Chuanyu Li ◽  
Wei Zhang ◽  
...  
Keyword(s):  
Blood Coagulation ◽  
Quartz Crystal Microbalance ◽  
Quartz Crystal ◽  
Clinical Laboratory ◽  
Point Of Care ◽  
Dissipation Factor ◽  
Parylene C ◽  
Adhesive Surface ◽  
Self Testing ◽  
Coagulation Testing

Blood coagulation function monitoring is important for people who are receiving anticoagulation treatment and a portable device is needed by these patients for blood coagulation self-testing. In this paper, a novel smartphone based blood coagulation test platform was proposed. It was developed based on parylene-C coated quartz crystal microbalance (QCM) dissipation measuring and analysis. The parylene-C coating constructed a robust and adhesive surface for fibrin capturing. The dissipation factor was obtained by measuring the frequency response of the sensor. All measured data were sent to a smartphone via Bluetooth for dissipation calculation and blood coagulation results computation. Two major coagulation indexes, activated partial thromboplastin time (APTT) and prothrombin time (PT) were measured on this platform compared with results by a commercial hemostasis system in a clinical laboratory. The measurement results showed that the adjusted R-square (R2) value for APTT and PT measurements were 0.985 and 0.961 respectively. The QCM dissipation method for blood coagulation measurement was reliable and effective and the platform together with the QCM dissipation method was a promising solution for point of care blood coagulation testing.

The modelling of blood coagulation using the quartz crystal microbalance

2013 ◽  
Vol 46 (3) ◽  
pp. 437-442 ◽  
Author(s):  
Vitaly Efremov ◽  
Anthony J. Killard ◽  
Barry Byrne ◽  
Ramji S. Lakshmanan
Keyword(s):  
Blood Coagulation ◽  
Quartz Crystal Microbalance ◽  
Quartz Crystal

Interaction of Clear Flavor Emulsions Containing Lemon Essential Oils with Lipid Bilayers via a Quartz Crystal Microbalance

2019 ◽  
Vol 25 (6) ◽  
pp. 879-884
Author(s):  
Takahiro Sakai ◽  
Hayato Seki ◽  
Shogo Yoshida ◽  
Hayato Hori ◽  
Hisashi Suzuki ◽  
...  
Keyword(s):  
Essential Oils ◽  
Lipid Bilayers ◽  
Quartz Crystal Microbalance ◽  
Quartz Crystal

Effect of Current Distribution on Quartz Crystal Microbalance Measurements

1998 ◽  
Vol 145 (2) ◽  
pp. 492-497 ◽  
Author(s):  
James J. Kelly ◽  
K. M. Anisur Rahman ◽  
Christopher J. Durning ◽  
Alan C. West
Keyword(s):  
Quartz Crystal Microbalance ◽  
Current Distribution ◽  
Quartz Crystal
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