Laser reflectance oximetry and Doppler flowmetry in assessment of complex physiological parameters of cutaneous blood microcirculation

Author(s):  
Andrey V. Dunaev ◽  
Victor V. Sidorov ◽  
Neil A. Stewart ◽  
Sergei G. Sokolovski ◽  
Edik U. Rafailov
2021 ◽  
Author(s):  
Guangjun Wang ◽  
Shuyong Jia ◽  
Xiaojing Song ◽  
Shuyou Wang ◽  
Weibo Zhang

Abstract A total of 30 healthy participants (Old, aged >40 years, n=12; Young, age<40, n=18) were recruited, and their bilateral upper limb blood flow was recorded. The results showed that on either the left or right side, the average oscillation intervals of the lower age were significantly higher than those of the older age and that on the left or right side, the average interval was negatively and weakly correlated with age. The current study provides a window to access age-related changes on the oscillation interval of cutaneous laser Doppler flowmetry.


Author(s):  
Tetana Stanishevska ◽  
Оksana Gorna ◽  
Daria Horban ◽  
Olga Yusupova

This research deals with the study of blood microcirculation peculiarities.Materials and methods. 72 students of Bogdan Khmelnytsky Melitopol State Pedagogical University, aged 18–19, were examined. The experimental research consisted of the study of blood microcirculation functional state by means of Laser Doppler flowmetry (LDF) method. It helped to evaluate the state of tissue blood-circulation and to detect individual-typological peculiarities of blood microcirculation under the influence of physical activity (before and after exercise).Results. Three types of blood microcirculation were identified by using LDF-metry. The normoemic type of blood microcirculation, characterized by the superposition of oscillatory rhythms and reflected the balance of the mechanisms of regulation of microcirculation. The hyperemic type, characterized by a «monotonous» LDF-gram with a high parameter of microcirculation, which reflects the relative predominance of metabolic mechanisms in the regulation of microcirculation. The hypoemic type, characterized by a «monotonous» LDF-gram with a low parameter of the microcirculation parameter, which reflects the decrease of vasomotor mechanisms in the regulation of microcirculation. According to the LDF-metric data, the examined students under intensive physical activity have a significant increase in microcirculatory status: by 6 % of the microcirculation parameter, by 28 % of the mean square deviation and by 45 % of the initial value of the coefficient of variation.Conclusions. This dynamics of microcirculation shows that under the influence of physical exertion, a person creates significant functional reserves for the redistribution of blood flow and for more perfect intraorgan capillary blood flow. It was found, that in the process of physical activity, morpho-functional rearrangements of the human cardiovascular system occur. This reaction is formed by several components of blood microcirculation: blood flow in the transport direction, regulating blood supply in accordance with the needs of tissues and the exchange component of the histochemical barrier


1994 ◽  
Vol 30 (2) ◽  
pp. 65-72 ◽  
Author(s):  
Andreas Bircher ◽  
Edith M. de Boer ◽  
Tove Agner ◽  
Jan E. Wahlberg ◽  
Jørgen Serup

2020 ◽  
Vol 10 (4) ◽  
pp. 63-65
Author(s):  
Vadim Astashov ◽  
Valentin Kozlov ◽  
Victor Sidorov, ◽  
Mihail Uloga ◽  
Inna Borodina ◽  
...  

In this study we used laser doppler flowmetry to investigate the parameters of peripheral blood flow in the upper extremities in young males both right- and left-handers. Based on the data obtained we found that in right-handers (dextrals) active mechanisms of regulation of blood microcirculation prevail on the leading hand, In left-handers (sinestrals) active and passive mechanisms of its regulation are involved in the regulation of blood flow on the leading hand (left) and on the opposite (right). However, the contribution of active mechanisms is lower than that of right-handers.


2019 ◽  
Vol 485 (1) ◽  
pp. 114-116
Author(s):  
G. I. Lobov ◽  
Yu. P. Gerasimenko ◽  
T. R. Moshonkina

Changes of the blood flow in the shin skin in the case of 12 healthy subjects by laser doppler flowmetry were observed under transcutaneous electrical spinal cord stimulation (TSCS) by subthreshold bipolar pulses with a frequency of 30 Hz were detected. It was found that the TSCS in the area of the vertebrae T11 and L1 leads to a significant increase in skin blood flow. With a stimulus intensity of 90% of the motor threshold, the microcirculation rate increased by more than 85% relative to baseline.The results of the study show that the stimulation of blood flow in the skin by TSCS is realized mainly due to the antidromic stimulation of sensory nerve fibers. An important mediator that contributes to vasodilation and increase of cutaneous blood flow in PSCS is nitric oxide (NO), which is predominantly endothelial in origin.


2018 ◽  
Vol 17 (3) ◽  
pp. 58-64
Author(s):  
E. V. Potapova ◽  
M. A. Filina ◽  
I. O. Kozlov ◽  
E. V. Zharkikh ◽  
V. V. Dremin ◽  
...  

The purpose of this work is to diagnose microcirculatory disorders in the tissues of psoriatic plaques in patients with psoriasis. Material and methods. Using the method of laser Doppler flowmetry (LDF), local hemodynamic parameters were studied in the place of psoriatic lesion of tissue and in uninvolved skin. Results. In the psoriatic plaque, there is an increase in average perfusion, myogenic and cardiac fluctuations, as well as nutritive blood flow as compared to the area of intact skin. Conclusions. The use of spectral analysis of the LDF signal has great potential for assessing the contribution of each link of the microvascular bed in the study the pathogenesis of psoriasis and evaluating the effectiveness of the therapy.


2017 ◽  
Author(s):  
M. V. Volkov ◽  
D. A. Kostrova ◽  
N. B. Margaryants ◽  
I. P. Gurov ◽  
N. P. Erofeev ◽  
...  

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