Influence of coherent light on blood microcirculation in human oral cavity mucous membrane: an objective monitoring by laser photoplethysmography and Doppler flowmetry

2004 ◽  
Author(s):  
Natalia A. Kharish ◽  
Alexander V. Lepilin ◽  
Vladislav V. Lychagov ◽  
Elena V. Safonkina ◽  
Alexey V. Sedykh ◽  
...  
2004 ◽  
Author(s):  
Sergey S. Ulyanov ◽  
Natalia A. Kharish ◽  
Alexander V. Lepilin ◽  
Mikhail Naumov ◽  
Elena V. Safonkina ◽  
...  

2004 ◽  
Author(s):  
Anastasia V. Ryzhkova ◽  
Sergey S. Ulyanov ◽  
Alexander V. Lepilin ◽  
Natalia A. Kharish

2005 ◽  
Author(s):  
Sergey S. Ulyanov ◽  
Haiying Chen ◽  
Natalia A. Kharish ◽  
Alexander V. Lepilin ◽  
Nisong Lin ◽  
...  

2017 ◽  
Vol 63 (5) ◽  
pp. 703-707
Author(s):  
Vladimir Nikolenko ◽  
Yekaterina Kochurova ◽  
Aleksandr Mukhanov

Modern data of the etiology of squamous cell carcinoma (SCC) of the mucous membrane of the oral cavity (MMOC) show an increasing prevalence of the disease, a high mortality rate despite the development of modern methods of diagnosis and treatment. SCC is a group of polyetiological diseases. Among the most often etiological factors the use of tobacco products is found as one of the main cause of the disease with the division into active or passive methods of their use, prevalence and potential pathogenicity. Also the risk of the development of SCC MMOC depends on the consumption of alcoholic product as the long-acting traumatic factor. There were analyzed and considered the most common precancerous diseases of the mucous membrane of the mouth, their private and common significance in the structure of precancerous diseases. There was revealed the high correlation between periodontal disease and the development of SCC MMOC, which corresponded to the general assumption about the risk of oncology development against the background of chronic infection in the oral cavity. There were identified new data of the relation between the carriers of some types of the viruses of human papillomavirus and the development of SCC MMOC. Particular understanding of the causal relation of presented on-copathology allowed judging the lack of preventive measures, the necessity of required qualification of specialists of dental and related profile.


1993 ◽  
Vol 43 (4) ◽  
pp. 631-639 ◽  
Author(s):  
Y. ETOH ◽  
F. E. DEWHIRST ◽  
B. J. PASTER ◽  
A. YAMAMOTO ◽  
N. GOTO

2009 ◽  
Vol 75 (11) ◽  
pp. 3777-3786 ◽  
Author(s):  
S. R. Vartoukian ◽  
R. M. Palmer ◽  
W. G. Wade

ABSTRACT Members of the phylum “Synergistetes” have frequently been detected in the human oral cavity at sites of dental disease, but they have rarely been detected in studies of oral health. Only two oral “Synergistetes” taxa are cultivable. The aims of this study were to investigate the diversity of “Synergistetes” in the oral cavity, to establish whether “Synergistetes” taxa are more strongly associated with periodontitis than with oral health, and to visualize unculturable “Synergistetes” in situ. Sixty samples (saliva, dental plaque, and mucosal swabs) were collected from five subjects with periodontitis and five periodontally healthy controls. Using phylum-specific 16S rRNA gene primers, “Synergistetes” were identified by PCR, cloning, and sequencing of 48 clones per PCR-positive sample. Subgingival plaque samples were labeled with probes targeting rRNA of unculturable oral “Synergistetes” using fluorescent in situ hybridization (FISH). Analysis of 1,664 clones revealed 12 “Synergistetes” operational taxonomic units (OTUs) at the 99% sequence identity level, 5 of which were novel. “Synergistetes” OTU 4.2 was found in significantly more subjects with periodontitis than controls (P = 0.048) and was more abundant in subgingival plaque at diseased sites than at healthy sites in subjects with periodontitis (P = 0.019) or controls (P = 0.019). FISH analysis revealed that unculturable oral “Synergistetes” cells were large curved bacilli. The human oral cavity harbors a diverse population of “Synergistetes.” “Synergistetes” OTU 4.2 is associated with periodontitis and may have a pathogenic role.


2021 ◽  
Vol 66 (1) ◽  
pp. 45-51
Author(s):  
V. M. Chervinets ◽  
Yu. V. Chervinets ◽  
A. V. Leont’eva ◽  
E. A. Kozlova ◽  
N. M. Stulov ◽  
...  

The microbiome of oral cavity in healthy people and patients with periodontitis was analyzed to determine their adhesive properties and the ability to form biofilms. The study involved 2 groups: healthy, 18 people, and an experimental group, 20 patients with chronic generalized periodontitis moderate severity of the disease. The average age of the studied people was 35-45 years. Material - dental plaque, scraping from the mucous membrane of the back of the tongue, the contents of the periodontal groove and periodontal pocket, as well as oral fluid. The main method of diagnostic was bacteriological. The average adhesion index (AAI) was used to determine adhesion level of microorganisms to epithelial cells of oral cavity’s mucous membrane. The microbiota’s ability to form biofilm was tested on glass and plastic surface. The microbiota of oral cavity of patients with periodontitis was characterized by decrease in the frequency of bacteria of the genera: Streptococcus, Peptostreptococcus, Peptococcus, and an increase in Staphylococcus aureus, Veillonella spp., Bacillus spp. The microbiota of the oral cavity of patients with generalized periodontitis has a greater ability to adhere to the cells of the mucous membrane than in healthy people, while their ability to form biofilms and exhibit pathogenic properties is enhanced. The biofilm formation of microorganisms in healthy and sick people differs both on glass and on plastic surfaces.


2018 ◽  
Vol 13 (14) ◽  
pp. 1611-1624 ◽  
Author(s):  
Maxime DM Fonkou ◽  
Jean-Charles Dufour ◽  
Grégory Dubourg ◽  
Didier Raoult

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