scholarly journals Noninvasive, in vivo imaging of blood-oxygenation dynamics within the mouse brain using photoacoustic microscopy

2009 ◽  
Vol 14 (2) ◽  
pp. 020502 ◽  
Author(s):  
Erich W. Stein ◽  
Konstantin Maslov ◽  
Lihong V. Wang
Keyword(s):  
Mouse Brain ◽  
In Vivo Imaging ◽  
Blood Oxygenation ◽  
Photoacoustic Microscopy

scholarly journals Noninvasive, in vivo imaging of the mouse brain using photoacoustic microscopy

2009 ◽  
Vol 105 (10) ◽  
pp. 102027 ◽  
Author(s):  
Erich W. Stein ◽  
Konstantin Maslov ◽  
Lihong V. Wang
Keyword(s):  
Mouse Brain ◽  
In Vivo Imaging ◽  
Photoacoustic Microscopy

scholarly journals High-resolution in vivo imaging of rhesus cerebral cortex with ultrafast portable photoacoustic microscopy

NeuroImage ◽  
2021 ◽  
pp. 118260
Author(s):  
Wei Qin ◽  
Qi Gan ◽  
Lei Yang ◽  
Yongchao Wang ◽  
Weizhi Qi ◽  
...  
Keyword(s):  
Cerebral Cortex ◽  
High Resolution ◽  
In Vivo Imaging ◽  
Photoacoustic Microscopy

scholarly journals Ultra-high-speed multi-parametric photoacoustic microscopy

2021 ◽  
Author(s):  
Song Hu ◽  
Fenghe Zhong
Keyword(s):  
High Speed ◽  
Laser Scanning ◽  
Ultrasonic Transducer ◽  
Hemoglobin Concentration ◽  
Blood Oxygenation ◽  
Flow Quantification ◽  
Photoacoustic Microscopy ◽  
Ultra High Speed ◽  
Working Distance

Multi-parametric photoacoustic microscopy (PAM) is uniquely capable of simultaneous, high-resolution mapping of blood hemoglobin concentration, oxygenation, and flow in vivo. However, its speed has been limited by the dense sampling required for blood flow quantification. To overcome this limitation, we have developed an ultra-high-speed multi-parametric PAM system, which enables simultaneous acquisition of ~500 densely sampled B-scans by superposing the rapid laser scanning across the line-shaped focus of a cylindrically focused ultrasonic transducer over the conventional mechanical scan of the optical-acoustic dual foci. A novel optical-acoustic combiner is designed and implemented to accommodate the short working distance of the transducer, enabling convenient confocal alignment of the dual foci in the reflection mode. This new system enables continuous monitoring of microvascular hemoglobin concentration, blood oxygenation, and flow over a 4.5 x 3 mm2 area in the awake mouse brain with high spatial and temporal resolution (6.9 μm and 0.3 Hz, respectively).

Migration and morphology changes of bone marrow cells in ischemic and peri-ischemic areas of the mouse brain demonstrated by chronic in vivo imaging

2005 ◽  
Vol 25 (1_suppl) ◽  
pp. S494-S494
Author(s):  
Alexy Tran Dinh ◽  
Nathalie Kubis ◽  
Yutaka Tomita ◽  
Bartosz Karaszewski ◽  
Yolande Calando ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Mouse Brain ◽  
In Vivo Imaging ◽  
Bone Marrow Cells ◽  
Morphology Changes ◽  
Marrow Cells

Functional photoacoustic microscopy for high-resolution and noninvasive in vivo imaging

2006 ◽  
Vol 24 (7) ◽  
pp. 848-851 ◽  
Author(s):  
Hao F Zhang ◽  
Konstantin Maslov ◽  
George Stoica ◽  
Lihong V Wang
Keyword(s):  
High Resolution ◽  
In Vivo Imaging ◽  
Photoacoustic Microscopy
Sign in / Sign up

Export Citation Format

Share Document