Differentiation of apoptosis from necrosis by dynamic changes of reduced nicotinamide adenine dinucleotide fluorescence lifetime in live cells

Hsing-Wen Wang; Vladimir Gukassyan; Chien-Tsun Chen; Yau-Huei Wei; Han-Wen Guo; Jia-Sin Yu; Fu-Jen Kao

doi:10.1117/1.2975831

Differentiation of apoptosis from necrosis by dynamic changes of reduced nicotinamide adenine dinucleotide fluorescence lifetime in live cells

Journal of Biomedical Optics ◽

10.1117/1.2975831 ◽

2008 ◽

Vol 13 (5) ◽

pp. 054011 ◽

Cited By ~ 67

Author(s):

Hsing-Wen Wang ◽

Vladimir Gukassyan ◽

Chien-Tsun Chen ◽

Yau-Huei Wei ◽

Han-Wen Guo ◽

...

Keyword(s):

Fluorescence Lifetime ◽

Nicotinamide Adenine Dinucleotide ◽

Nicotinamide Adenine ◽

Live Cells ◽

Dynamic Changes ◽

Reduced Nicotinamide Adenine Dinucleotide

Download Full-text

Reduced nicotinamide adenine dinucleotide fluorescence lifetime detected poly(adenosine-5ʹ-diphosphate-ribose) polymerase-1-mediated cell death and therapeutic effect of pyruvate

Journal of Biomedical Optics ◽

10.1117/1.3590204 ◽

2011 ◽

Vol 16 (6) ◽

pp. 068001 ◽

Cited By ~ 5

Author(s):

Han-Wen Guo ◽

Yau-Huei Wei ◽

Hsing-Wen Wang

Keyword(s):

Cell Death ◽

Therapeutic Effect ◽

Fluorescence Lifetime ◽

Nicotinamide Adenine Dinucleotide ◽

Nicotinamide Adenine ◽

Reduced Nicotinamide Adenine Dinucleotide

Download Full-text

Increase of reduced nicotinamide adenine dinucleotide fluorescence lifetime precedes mitochondrial dysfunction in staurosporine-induced apoptosis of HeLa cells

Journal of Biomedical Optics ◽

10.1117/1.3560513 ◽

2011 ◽

Vol 16 (3) ◽

pp. 036008 ◽

Cited By ~ 18

Author(s):

Jia-Sin Yu ◽

Han-Wen Guo ◽

Chih-Hao Wang ◽

Yau-Huei Wei ◽

Hsing-Wen Wang

Keyword(s):

Mitochondrial Dysfunction ◽

Fluorescence Lifetime ◽

Hela Cells ◽

Nicotinamide Adenine Dinucleotide ◽

Nicotinamide Adenine ◽

Induced Apoptosis ◽

Reduced Nicotinamide Adenine Dinucleotide

Download Full-text

Monitoring Cellular Metabolism with Fluorescence Lifetime of Reduced Nicotinamide Adenine Dinucleotide

The Journal of Physical Chemistry C ◽

10.1021/jp810931u ◽

2009 ◽

Vol 113 (27) ◽

pp. 11532-11540 ◽

Cited By ~ 72

Author(s):

Vladimir V. Ghukasyan ◽

Fu-Jen Kao

Keyword(s):

Fluorescence Lifetime ◽

Nicotinamide Adenine Dinucleotide ◽

Cellular Metabolism ◽

Nicotinamide Adenine ◽

Reduced Nicotinamide Adenine Dinucleotide

Download Full-text

Monitoring Cellular Metabolism with Fluorescence Lifetime of Reduced Nicotinamide Adenine Dinucleotide

Asia Communications and Photonics Conference and Exhibition ◽

10.1364/acp.2009.fe4 ◽

2009 ◽

Cited By ~ 1

Author(s):

Vladimir V. Ghukasyan ◽

Fu-Jen Kao

Keyword(s):

Fluorescence Lifetime ◽

Nicotinamide Adenine Dinucleotide ◽

Cellular Metabolism ◽

Nicotinamide Adenine ◽

Reduced Nicotinamide Adenine Dinucleotide

Download Full-text

Reduced nicotinamide adenine dinucleotide fluorescence lifetime separates human mesenchymal stem cells from differentiated progenies

Journal of Biomedical Optics ◽

10.1117/1.2990752 ◽

2008 ◽

Vol 13 (5) ◽

pp. 050505 ◽

Cited By ~ 34

Author(s):

Han-Wen Guo ◽

Chien-Tsun Chen ◽

Yau-Huei Wei ◽

Oscar K. Lee ◽

Vladimir Gukassyan ◽

...

Keyword(s):

Stem Cells ◽

Mesenchymal Stem Cells ◽

Fluorescence Lifetime ◽

Nicotinamide Adenine Dinucleotide ◽

Human Mesenchymal Stem Cells ◽

Nicotinamide Adenine ◽

Reduced Nicotinamide Adenine Dinucleotide

Download Full-text

Effect of lidocaine on dynamic changes in cortical reduced nicotinamide adenine dinucleotide fluorescence during transient focal cerebral ischemia in rats

Neuroscience ◽

10.1016/j.neuroscience.2013.01.010 ◽

2013 ◽

Vol 235 ◽

pp. 59-69 ◽

Cited By ~ 1

Author(s):

H. Naito ◽

Y. Takeda ◽

T. Danura ◽

I.S. Kass ◽

K. Morita

Keyword(s):

Cerebral Ischemia ◽

Nicotinamide Adenine Dinucleotide ◽

Focal Cerebral Ischemia ◽

Nicotinamide Adenine ◽

Dynamic Changes ◽

Transient Focal Cerebral Ischemia ◽

Reduced Nicotinamide Adenine Dinucleotide

Download Full-text

Faculty Opinions recommendation of Reduced nicotinamide adenine dinucleotide phosphate oxidase 2 plays a key role in stellate cell activation and liver fibrogenesis in vivo.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.5807958.5789056 ◽

2010 ◽

Author(s):

Jonathan A Dranoff ◽

Michel Fausther

Keyword(s):

Nicotinamide Adenine Dinucleotide ◽

Cell Activation ◽

Stellate Cell ◽

Nicotinamide Adenine Dinucleotide Phosphate ◽

Nicotinamide Adenine ◽

Liver Fibrogenesis ◽

Reduced Nicotinamide Adenine Dinucleotide

Download Full-text

Reduced Nicotinamide Adenine Dinucleotide (NADH) Fluorescence for the Detection of Cell Death

Anti-Cancer Agents in Medicinal Chemistry ◽

10.2174/187152009789377718 ◽

2009 ◽

Vol 9 (9) ◽

pp. 1012-1017 ◽

Cited By ~ 32

Author(s):

Hsing-Wen Wang ◽

Yau-Huei Wei ◽

Han-Wen Guo

Keyword(s):

Cell Death ◽

Nicotinamide Adenine Dinucleotide ◽

Nicotinamide Adenine ◽

Nadh Fluorescence ◽

Reduced Nicotinamide Adenine Dinucleotide

Download Full-text

Partial Characterization of the Nuclear Reduced Nicotinamide Adenine Dinucleotide Phosphate: Δ4-3-Ketosteroid 5α-Oxidoreductase of Rat Prostate

Journal of Biological Chemistry ◽

10.1016/s0021-9258(18)62328-2 ◽

1971 ◽

Vol 246 (8) ◽

pp. 2584-2593

Author(s):

D.W. Frederiksen ◽

Jean D. Wilson

Keyword(s):

Nicotinamide Adenine Dinucleotide ◽

Nicotinamide Adenine Dinucleotide Phosphate ◽

Partial Characterization ◽

Nicotinamide Adenine ◽

Rat Prostate ◽

Reduced Nicotinamide Adenine Dinucleotide

Download Full-text

A Form of Reduced Nicotinamide Adenine Dinucleotide-Cytochrome b5 Reductase Containing Both the Catalytic Site and an Additional Hydrophobic Membrane-binding Segment

Journal of Biological Chemistry ◽

10.1016/s0021-9258(19)44337-8 ◽

1973 ◽

Vol 248 (3) ◽

pp. 793-799 ◽

Cited By ~ 17

Author(s):

Lawrence Spatz ◽

Philipp Strittmatter

Keyword(s):

Nicotinamide Adenine Dinucleotide ◽

Cytochrome B5 ◽

Membrane Binding ◽

Catalytic Site ◽

Nicotinamide Adenine ◽

Hydrophobic Membrane ◽

Cytochrome B5 Reductase ◽

Reduced Nicotinamide Adenine Dinucleotide

Download Full-text