scholarly journals In vivo optical characterization of human prostate tissue using near-infrared time-resolved spectroscopy

2007 ◽  
Vol 12 (1) ◽  
pp. 014022 ◽  
Author(s):  
Tomas Svensson ◽  
Stefan Andersson-Engels ◽  
Margrét Einarsdóttír ◽  
Katarina Svanberg
Keyword(s):  
Near Infrared ◽  
Optical Characterization ◽  
Prostate Tissue ◽  
Human Prostate ◽  
Time Resolved ◽  
Time Resolved Spectroscopy ◽  
Human Prostate Tissue

scholarly journals Numerical simulation modeling of the irreversible electroporation treatment zone for focal therapy of prostate cancer, correlation with whole-mount pathology and T2-weighted MRI sequences

2019 ◽  
Vol 11 ◽  
pp. 175628721985230 ◽  
Author(s):  
Matthijs J. Scheltema ◽  
Tim J. O’Brien ◽  
Willemien van den Bos ◽  
Daniel M. de Bruin ◽  
Rafael V. Davalos ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Irreversible Electroporation ◽  
Prostate Tissue ◽  
Human Prostate ◽  
Ablation Zone ◽  
Electrical Field ◽  
Whole Mount ◽  
Human Prostate Tissue ◽  
Mri Sequences

Background: At present, it is not possible to predict the ablation zone volume following irreversible electroporation (IRE) for prostate cancer (PCa). This study aimed to determine the necessary electrical field threshold to ablate human prostate tissue in vivo with IRE. Methods: In this prospective multicenter trial, patients with localized PCa were treated with IRE 4 weeks before their scheduled radical prostatectomy. In 13 patients, numerical models of the electrical field were generated and compared with the ablation zone volume on whole-mount pathology and T2-weighted magnetic resonance imaging (MRI) sequences. Volume-generating software was used to calculate the ablation zone volumes on histology and MRI. The electric field threshold to ablate prostate tissue was determined for each patient. Results: A total of 13 patients were included for histological and simulation analysis. The median electrical field threshold was 550 V/cm (interquartile range 383–750 V/cm) for the software-generated histology volumes. The median electrical field threshold was 500 V/cm (interquartile range 386–580 V/cm) when the ablation zone volumes were used from the follow-up MRI. Conclusions: The electrical field threshold to ablate human prostate tissue in vivo was determined using whole-mount pathology and MRI. These thresholds may be used to develop treatment planning or monitoring software for IRE prostate ablation; however, further optimization of simulation methods are required to decrease the variance that was observed between patients.

In vivo time-resolved multi-distance spectroscopy of human forehead: a step towards optical characterization of brain tissue

2006 ◽  
Author(s):  
D. Comelli ◽  
A. Pifferi ◽  
P. Taroni ◽  
A. Torricelli ◽  
R. Cubeddu ◽  
...  
Keyword(s):  
Brain Tissue ◽  
Optical Characterization ◽  
Time Resolved

scholarly journals Single-voxel oversampled J-resolved spectroscopy of in vivo human prostate tissue

2001 ◽  
Vol 45 (6) ◽  
pp. 973-980 ◽  
Author(s):  
Mark G. Swanson ◽  
Daniel B. Vigneron ◽  
Tuan-Khanh C. Tran ◽  
Napapon Sailasuta ◽  
Ralph E. Hurd ◽  
...  
Keyword(s):  
Prostate Tissue ◽  
Human Prostate ◽  
Single Voxel ◽  
Human Prostate Tissue

Cloning and characterization of the α1-antichymotrypsin produced by human prostate tissue

The Prostate ◽  
1998 ◽  
Vol 34 (3) ◽  
pp. 155-161 ◽  
Author(s):  
Guan Wu ◽  
Hans Lilja ◽  
Abraham T.K. Cockett ◽  
Sten Gershagen
Keyword(s):  
Prostate Tissue ◽  
Human Prostate ◽  
Human Prostate Tissue

In Vivo Optical Characterization of Human Prostatic Tissue using Time-resolved Near Infra-red Spectroscopy

2006 ◽  
Author(s):  
Tomas Svensson ◽  
Stefan Andersson-Engels ◽  
Margét Einarsdottir ◽  
Katarina Svanberg
Keyword(s):  
Optical Characterization ◽  
Prostatic Tissue ◽  
Time Resolved ◽  
Infra Red

Development and characterization of efficient xenograft models for benign and malignant human prostate tissue

The Prostate ◽  
2005 ◽  
Vol 64 (2) ◽  
pp. 149-159 ◽  
Author(s):  
Yuzhuo Wang ◽  
Monica P. Revelo ◽  
Daniel Sudilovsky ◽  
Mei Cao ◽  
Wilfred G. Chen ◽  
...  
Keyword(s):  
Prostate Tissue ◽  
Human Prostate ◽  
Human Prostate Tissue ◽  
Xenograft Models
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