Development and characterization of efficient xenograft models for benign and malignant human prostate tissue

The Prostate ◽  
2005 ◽  
Vol 64 (2) ◽  
pp. 149-159 ◽  
Author(s):  
Yuzhuo Wang ◽  
Monica P. Revelo ◽  
Daniel Sudilovsky ◽  
Mei Cao ◽  
Wilfred G. Chen ◽  
...  
Keyword(s):  
Prostate Tissue ◽  
Human Prostate ◽  
Human Prostate Tissue ◽  
Xenograft Models

Cloning and characterization of the α1-antichymotrypsin produced by human prostate tissue

The Prostate ◽  
1998 ◽  
Vol 34 (3) ◽  
pp. 155-161 ◽  
Author(s):  
Guan Wu ◽  
Hans Lilja ◽  
Abraham T.K. Cockett ◽  
Sten Gershagen
Keyword(s):  
Prostate Tissue ◽  
Human Prostate ◽  
Human Prostate Tissue

Pathologic Characterization of Human Prostate Tissue with Proton MR Spectroscopy

Radiology ◽  
2003 ◽  
Vol 228 (1) ◽  
pp. 144-151 ◽  
Author(s):  
Peter Swindle ◽  
Simon McCredie ◽  
Peter Russell ◽  
Uwe Himmelreich ◽  
Mohammed Khadra ◽  
...  
Keyword(s):  
Mr Spectroscopy ◽  
Prostate Tissue ◽  
Human Prostate ◽  
Proton Mr Spectroscopy ◽  
Human Prostate Tissue

272: Biological Characterization of XMRV, a Novel Retrovirus Isolated from Human Prostate Tissue

2007 ◽  
Vol 177 (4S) ◽  
pp. 91-91
Author(s):  
Beihua Dong ◽  
Sanguu Kim ◽  
Seunghee Hong ◽  
Jaydip Das Gupta ◽  
Krishnamurthy Malathi ◽  
...  
Keyword(s):  
Prostate Tissue ◽  
Human Prostate ◽  
Biological Characterization ◽  
Human Prostate Tissue

scholarly journals Characterization of Precursor-Dependent Steroidogenesis in Human Prostate Cancer Models

Cancers ◽  
2018 ◽  
Vol 10 (10) ◽  
pp. 343 ◽  
Author(s):  
Subrata Deb ◽  
Steven Pham ◽  
Dong-Sheng Ming ◽  
Mei Chin ◽  
Hans Adomat ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Cell Lines ◽  
Messenger Rna ◽  
Prostate Tissue ◽  
Human Prostate ◽  
Classical Pathway ◽  
Castration Resistant ◽  
Cancer Models ◽  
Human Prostate Tissue

Castration-resistant prostate tumors acquire the independent capacity to generate androgens by upregulating steroidogenic enzymes or using steroid precursors produced by the adrenal glands for continued growth and sustainability. The formation of steroids was measured by liquid chromatography-mass spectrometry in LNCaP and 22Rv1 prostate cancer cells, and in human prostate tissues, following incubation with steroid precursors (22-OH-cholesterol, pregnenolone, 17-OH-pregnenolone, progesterone, 17-OH-progesterone). Pregnenolone, progesterone, 17-OH-pregnenolone, and 17-OH-progesterone increased C21 steroid (5-pregnan-3,20-dione, 5-pregnan-3,17-diol-20-one, 5-pregnan-3-ol-20-one) formation in the backdoor pathway, and demonstrated a trend of stimulating dihydroepiandrosterone or its precursors in the backdoor pathway in LNCaP and 22Rv1 cells. The precursors differentially affected steroidogenic enzyme messenger RNA (mRNA) expressions in the cell lines. The steroidogenesis following incubation of human prostate tissue with 17-OH-pregnenolone and progesterone produced trends similar to those observed in cell lines. Interestingly, the formation of C21 steroids from classical pathway was not stimulated but backdoor pathway steroids (e.g., 5-pregnan-3,20-dione, 5-pregnan-3-ol-20-one) were elevated following incubations with prostate tissues. Overall, C21 steroids were predominantly formed in the classical as well as backdoor pathways, and steroid precursors induced a diversion of steroidogenesis to the backdoor pathway in both cell lines and human prostate tissue, and influenced adaptive steroidogenesis to form C21 steroids.

scholarly journals In vivo optical characterization of human prostate tissue using near-infrared time-resolved spectroscopy

2007 ◽  
Vol 12 (1) ◽  
pp. 014022 ◽  
Author(s):  
Tomas Svensson ◽  
Stefan Andersson-Engels ◽  
Margrét Einarsdóttír ◽  
Katarina Svanberg
Keyword(s):  
Near Infrared ◽  
Optical Characterization ◽  
Prostate Tissue ◽  
Human Prostate ◽  
Time Resolved ◽  
Time Resolved Spectroscopy ◽  
Human Prostate Tissue
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