Multifunctional natural polymer-based metallic implant surface modifications

2021 ◽  
Vol 16 (2) ◽  
pp. 020803
Author(s):  
Ahmet Engin Pazarçeviren ◽  
Ayşen Tezcaner ◽  
Zafer Evis
Keyword(s):  
Surface Modifications ◽  
Natural Polymer ◽  
Implant Surface ◽  
Metallic Implant

scholarly journals The Impact of Dental Implant Surface Modifications on Osseointegration and Biofilm Formation

2021 ◽  
Vol 10 (8) ◽  
pp. 1641
Author(s):  
Stefanie Kligman ◽  
Zhi Ren ◽  
Chun-Hsi Chung ◽  
Michael Angelo Perillo ◽  
Yu-Cheng Chang ◽  
...  
Keyword(s):  
Dental Implant ◽  
Biofilm Formation ◽  
Bacterial Colonization ◽  
Surface Modifications ◽  
Implant Surface ◽  
Oral Rehabilitation ◽  
Surface Design ◽  
Polyether Ether Ketone ◽  
Dental Implant Surface ◽  
The Impact

Implant surface design has evolved to meet oral rehabilitation challenges in both healthy and compromised bone. For example, to conquer the most common dental implant-related complications, peri-implantitis, and subsequent implant loss, implant surfaces have been modified to introduce desired properties to a dental implant and thus increase the implant success rate and expand their indications. Until now, a diversity of implant surface modifications, including different physical, chemical, and biological techniques, have been applied to a broad range of materials, such as titanium, zirconia, and polyether ether ketone, to achieve these goals. Ideal modifications enhance the interaction between the implant’s surface and its surrounding bone which will facilitate osseointegration while minimizing the bacterial colonization to reduce the risk of biofilm formation. This review article aims to comprehensively discuss currently available implant surface modifications commonly used in implantology in terms of their impact on osseointegration and biofilm formation, which is critical for clinicians to choose the most suitable materials to improve the success and survival of implantation.

Calcium Phosphate-Coated Titanium Implants in the Mandible: Limitations of the in vivo Minipig Model

2020 ◽  
Vol 61 (6) ◽  
pp. 177-187
Author(s):  
Till Kämmerer ◽  
Tony Lesmeister ◽  
Victor Palarie ◽  
Eik Schiegnitz ◽  
Andrea Schröter ◽  
...  
Keyword(s):  
Calcium Phosphate ◽  
Statistical Difference ◽  
Surface Modifications ◽  
Titanium Implants ◽  
In Vivo Model ◽  
Implant Surface ◽  
Press Fit ◽  
Endosseous Implant ◽  
Bone To Implant Contact

Introduction: We aimed to compare implant osseointegration with calcium phosphate (CaP) surfaces and rough subtractive-treated sandblasted/acid etched surfaces (SA) in an in vivo minipig mandible model. Materials and Methods: A total of 36 cylindrical press-fit implants with two different surfaces (CaP, n = 18; SA, n = 18) were inserted bilaterally into the mandible of 9 adult female minipigs. After 2, 4, and 8 weeks, we analyzed the cortical bone-to-implant contact (cBIC; %) and area coverage of bone-to-implant contact within representative bone chambers (aBIC; %). Results: After 2 weeks, CaP implants showed no significant increase in cBIC and aBIC compared to SA (cBIC: mean 38 ± 5 vs. 16 ± 11%; aBIC: mean 21 ± 1 vs. 6 ± 9%). Two CaP implants failed to achieve osseointegration. After 4 weeks, no statistical difference between CaP and SA was seen for cBIC (mean 54 ± 15 vs. 43 ± 16%) and aBIC (mean 43 ± 28 vs. 32 ± 6). However, we excluded two implants in each group due to failure of osseointegration. After 8 weeks, we observed no significant intergroup differences (cBIC: 18 ± 9 vs. 18 ± 20%; aBIC: 13 ± 8 vs. 16 ± 9%). Again, three CaP implants and two SA implants had to be excluded due to failure of osseointegration. Conclusion: Due to multiple implant losses, we cannot recommend the oral mandibular minipig in vivo model for future endosseous implant research. Considering the higher rate of osseointegration failure, CaP coatings may provide an alternative to common subtractive implant surface modifications in the early phase post-insertion.

scholarly journals Erratum to: Biomechanical and histological evaluation of four different titanium implant surface modifications: an experimental study in the rabbit tibia

2015 ◽  
Vol 19 (7) ◽  
pp. 1699-1699 ◽  
Author(s):  
José Luis Calvo-Guirado ◽  
Marta Satorres ◽  
Bruno Negri ◽  
Piedad Ramirez-Fernandez ◽  
Jose Eduardo Maté-Sánchez de Val ◽  
...  
Keyword(s):  
Experimental Study ◽  
Titanium Implant ◽  
Surface Modifications ◽  
Histological Evaluation ◽  
Implant Surface ◽  
Rabbit Tibia ◽  
Titanium Implant Surface

scholarly journals Biological Responses to New Advanced Surface Modifications of Endosseous Medical Implants

2009 ◽  
Vol 2 ◽  
pp. BTRI.S3150 ◽  
Author(s):  
Weerachai Singhatanadgit
Keyword(s):  
Surface Modifications ◽  
Modern Medicine ◽  
Medical Implants ◽  
Implant Surface ◽  
Implantable Medical Devices ◽  
Implant Placement ◽  
Biological Responses ◽  
Wide Range ◽  
Tissue Responses ◽  
Surface Modification Techniques

Implantable medical devices are increasingly important in the practice of modern medicine. However, patients with severely poor bone quality and quantity require highest implant osseointegration for the long-term success. A number of newly-developed advanced surface modifications of medical implants have recently been introduced to the medical implant system. Understanding the mechanisms by which osteogenic cells respond to such materials is therefore of major importance in developing the most effective materials to promote functional osseointegration. Diverse studies using materials with a wide range of new surface modification techniques have demonstrated the pivotal role of surface treatments in cell adhesion, proliferation and lineage specific differentiation. These events underlie the tissue responses required for bone healing following implant placement, with the interaction between adsorbed proteins on the implant surface and surrounding cells eliciting body responses to the treated implant surface. This review illustrates tissue responses to the implant material following implant placement and highlights cellular responses to new advanced implant surface modifications. Such information is of utmost importance to further develop several new advanced surface modifications to be used in the new era medical implantable devices.

Implant Surface Modification and Osseointegration-Past, Present and Future

2014 ◽  
Vol 8 (2) ◽  
pp. 113-118 ◽  
Author(s):  
A Kumar ◽  
V Kumar ◽  
M Goel ◽  
R Mehta ◽  
G Bhayana ◽  
...  
Keyword(s):  
Surface Modification ◽  
Surface Properties ◽  
Dental Implant ◽  
Research Evidence ◽  
Surface Modifications ◽  
Biological Fixation ◽  
Implant Surface ◽  
Jaw Bones

ABSTRACT Biological fixation between the dental implant surfaces and jaw bones should be considered a prerequisite for the long-term success of implant-supported prostheses. The implant surface modifications gained an important and decisive place in implant research over the last years. Nowadays, a large number of implant types with a great variety of surface properties and other features are commercially available and have to be treated with caution. Although surface modifications have been shown to enhance osseointegration at early implantation times, for example, the clinician should look for research evidence before selecting a dental implant for a specific use.

Comparison of two dental implant surface modifications on implants with same macrodesign: an experimental study in the pelvic sheep model

2014 ◽  
Vol 26 (8) ◽  
pp. 898-908 ◽  
Author(s):  
Sabrina Ernst ◽  
Stefan Stübinger ◽  
Peter Schüpbach ◽  
Michéle Sidler ◽  
Karina Klein ◽  
...  
Keyword(s):  
Experimental Study ◽  
Dental Implant ◽  
Surface Modifications ◽  
Implant Surface ◽  
Sheep Model ◽  
Dental Implant Surface

scholarly journals Impact of Dental Implant Surface Modifications on Osseointegration

2016 ◽  
Vol 2016 ◽  
pp. 1-16 ◽  
Author(s):  
Ralf Smeets ◽  
Bernd Stadlinger ◽  
Frank Schwarz ◽  
Benedicta Beck-Broichsitter ◽  
Ole Jung ◽  
...  
Keyword(s):  
Dental Implants ◽  
Survival Rates ◽  
Surface Modifications ◽  
Comprehensive Overview ◽  
Implant Surface ◽  
Oral Rehabilitation ◽  
New Techniques ◽  
Surface Design ◽  
Dental Implant Surface ◽  
Experimental Surface

Objective.The aim of this paper is to review different surface modifications of dental implants and their effect on osseointegration. Common marketed as well as experimental surface modifications are discussed.Discussion.The major challenge for contemporary dental implantologists is to provide oral rehabilitation to patients with healthy bone conditions asking for rapid loading protocols or to patients with quantitatively or qualitatively compromised bone. These charging conditions require advances in implant surface design. The elucidation of bone healing physiology has driven investigators to engineer implant surfaces that closely mimic natural bone characteristics. This paper provides a comprehensive overview of surface modifications that beneficially alter the topography, hydrophilicity, and outer coating of dental implants in order to enhance osseointegration in healthy as well as in compromised bone. In the first part, this paper discusses dental implants that have been successfully used for a number of years focusing on sandblasting, acid-etching, and hydrophilic surface textures. Hereafter, new techniques like Discrete Crystalline Deposition, laser ablation, and surface coatings with proteins, drugs, or growth factors are presented.Conclusion.Major advancements have been made in developing novel surfaces of dental implants. These innovations set the stage for rehabilitating patients with high success and predictable survival rates even in challenging conditions.

scholarly journals Influence of implant surfaces on osseointegration

2010 ◽  
Vol 21 (6) ◽  
pp. 471-481 ◽  
Author(s):  
Arthur Belém Novaes Jr ◽  
Sérgio Luis Scombatti de Souza ◽  
Raquel Rezende Martins de Barros ◽  
Karina Kimiko Yamashina Pereira ◽  
Giovanna Iezzi ◽  
...  
Keyword(s):  
Dental Implant ◽  
Bone Morphogenetic Proteins ◽  
Dental Treatment ◽  
Surface Modifications ◽  
In Vivo Studies ◽  
Treatment Modalities ◽  
Biological Fixation ◽  
Implant Surface

The biological fixation between the dental implant surfaces and jaw bones should be considered a prerequisite for the long-term success of implant-supported prostheses. In this context, the implant surface modifications gained an important and decisive place in implant research over the last years. As the most investigated topic in, it aided the development of enhanced dental treatment modalities and the expansion of dental implant use. Nowadays, a large number of implant types with a great variety of surface properties and other features are commercially available and have to be treated with caution. Although surface modifications have been shown to enhance osseointegration at early implantation times, for example, the clinician should look for research evidence before selecting a dental implant for a specific use. This paper reviews the literature on dental implant surfaces by assessing in vitro and in vivo studies to show the current perspective of implant development. The review comprises quantitative and qualitative results on the analysis of bone-implant interface using micro and nano implant surface topographies. Furthermore, the perspective of incorporating biomimetic molecules (e.g.: peptides and bone morphogenetic proteins) to the implant surface and their effects on bone formation and remodeling around implants are discussed.

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