Polystyrene-block-polyethylene oxide thin films: In vitro cytocompatibility and protein adsorption testing

2020 ◽  
Vol 15 (1) ◽  
pp. 011003
Author(s):  
Isabela Monteiro A. ◽  
Tarek Kollmetz ◽  
David S. Musson ◽  
Sue R. McGlashan ◽  
Jenny Malmström
2010 ◽  
Vol 1277 ◽  
Author(s):  
Phaedra Silva-Bermudez ◽  
Sandra E. Rodil

The adsorption of bovine serum albumin (BSA) and fibrinogen proteins dissolved on Phosphate buffer solution onto Ta, Nb and Ti oxide thin films was studied. The metal oxide thin films were deposited by magnetron sputtering on Si(100) wafers and characterized by contact angle measurements and profilometry. Spectroscopic ellipsometry was employed to characterize the kinetics of the protein adsorption process in-situ at the solid-liquid interface and the optical properties of the adsorbed protein layer formed after 45 minutes of immersion of the thin film in the protein solution. Infrared spectroscopy was used to study the proteins within the adsorbed layer. A trend indicating that the surface mass density of the adsorbed protein layer increases as the Rt (peak-to-valley height) surface roughness parameter increases was observed for fibrinogen and BSA. An increment in the surface mass density of the adsorbed protein layer was also observed onto surfaces with higher polar components of the surface energy. BSA and fibrinogen seemed to more readily adsorbed onto tantalum oxide than onto titanium oxide.


2017 ◽  
Vol 265 ◽  
pp. 102-110 ◽  
Author(s):  
Memoon Sajid ◽  
Ghayas Uddin Siddiqui ◽  
Soo Wan Kim ◽  
Kyoung Hoan Na ◽  
Young Soo Choi ◽  
...  

1992 ◽  
Vol 293 ◽  
Author(s):  
Joyce Y. Wong ◽  
Robert S. Langer ◽  
Donald E. Ingber

AbstractThin films of polypyrrole were synthesized using both chemical oxidative and electrochemical methods. The resulting oxidized films were characterized by UV/VIS spectroscopy, contact angle and conductivity measurements. In vitro studies suggest that extracellular matrix molecules, such as fibronectin, adsorb efficiently onto polypyrrole thin films and that 3T3 Balb/c mouse fibroblasts attach and spread normally on polypyrrole.


Soft Matter ◽  
2017 ◽  
Vol 13 (33) ◽  
pp. 5597-5603 ◽  
Author(s):  
Daniel E. Martínez-Tong ◽  
Luis A. Miccio ◽  
Angel Alegria

We present a detailed Atomic Force Microscopy based study on the ionic transport properties of polyethylene oxide (PEO) thin films prepared under different conditions.


Author(s):  
I. A. Rauf

To understand the electronic conduction mechanism in Sn-doped indium oxide thin films, it is important to study the effect of dopant atoms on the neighbouring indium oxide lattice. Ideally Sn is a substitutional dopant at random indium sites. The difference in valence (Sn4+ replaces In3+) requires that an extra electron is donated to the lattice and thus contributes to the free carrier density. But since Sn is an adjacent member of the same row in the periodic table, the difference in the ionic radius (In3+: 0.218 nm; Sn4+: 0.205 nm) will introduce a strain in the indium oxide lattice. Free carrier electron waves will no longer see a perfect periodic lattice and will be scattered, resulting in the reduction of free carrier mobility, which will lower the electrical conductivity (an undesirable effect in most applications).One of the main objectives of the present investigation is to understand the effects of the strain (produced by difference in the ionic radius) on the microstructure of the indium oxide lattice when the doping level is increased to give high carrier densities. Sn-doped indium oxide thin films were prepared with four different concentrations: 9, 10, 11 and 12 mol. % of SnO2 in the starting material. All the samples were prepared at an oxygen partial pressure of 0.067 Pa and a substrate temperature of 250°C using an Edwards 306 coating unit with an electron gun attachment for heating the crucible. These deposition conditions have been found to give optimum electrical properties in Sn-doped indium oxide films. A JEOL 2000EX transmission electron microscope was used to investigate the specimen microstructure.


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