scholarly journals The role of ultrasonography in head and neck Non-Melanoma Skin Cancer approach: an update with a review of the literature

2020 ◽  
Author(s):  
Tiberiu Tamas ◽  
Cristian Dinu ◽  
Manuela Lenghel ◽  
Grigore Băciuț ◽  
Simion Bran ◽  
...  
Keyword(s):  
Skin Cancer ◽  
New Technologies ◽  
Treatment Plan ◽  
Full Range ◽  
Excisional Biopsy ◽  
Skin Cancer Prevention ◽  
Depth Of Invasion ◽  
Non Melanoma Skin Cancer ◽  
The Face ◽  
Melanoma Skin

Non-Melanoma Skin Cancer is one of the most common cancer types and the face is the most affected region. The diagnosis of the skin cancer relies on clinical inspection, palpation, dermoscopy followed by incisional or excisional biopsy. When skin cancers are removed from the face, many factors are involved, including aesthetics. In addition, surgical planning with preoperative acknowledgement of the tumour margins is often the key to avoid incomplete excision, the need for reintervention, or in the prevention of functional and aesthetical defects in the treatment of skin tumours. In recent years, the development of new technologies in sonography, including high frequencies transducers can provide a full range of data. It can offer valuable information regarding the size of the tumour including the depth of invasion, the extent of the tumour, histology and subtypes of the lesions which are helpful for the treatment plan. It also may be efficient in detection of positive margins after surgery and it could play a role in the treatment of skin cancer, prevention of local recurrences and overall control of the disease. K

scholarly journals The incidence and clinical analysis of non-melanoma skin cancer

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Magdalena Ciążyńska ◽  
Grażyna Kamińska-Winciorek ◽  
Dariusz Lange ◽  
Bogumił Lewandowski ◽  
Adam Reich ◽  
...  
Keyword(s):  
Skin Cancer ◽  
Cell Carcinoma ◽  
Treatment Strategies ◽  
Cancer Registries ◽  
Clinical Analysis ◽  
Tumour Site ◽  
Non Melanoma Skin Cancer ◽  
Skin Cancers ◽  
The Face ◽  
Melanoma Skin

AbstractNon-melanoma skin cancers (NMSCs) are the most common malignancies diagnosed in Caucasian populations. Basal cell carcinoma (BCC) is the most frequent skin cancer, followed by squamous cell carcinoma (SCC). Unfortunately, most European cancer registries do not record individual types of NMSC. To evaluate the incidence of primary BCCs and SCCs regarding age, sex, tumour site and tumour subtype to determine trends in epidemiology of both cancers. Retrospective analysis of BCCs and SCCs diagnosed and treated across seven sites in Poland from 1999 to 2019. We recorded 13,913 NMSCs occurring in 10,083 patients. BCC represented 85.2% of all cases. SCC patients were older than BCC patients (77.1 ± 11.3 years vs. 70.1 ± 12.3 years, p < 0.01). The nodular subtype was the most common subtype of BCC, followed by the superficial and infiltrative subtypes. The superficial BCC subtype was more common on photoprotected areas (p < 0.01), whereas the nodular BCC subtype occurred on the face (p < 0.01). The high-risk SCC subtypes were more common on face compared to low-risk SCC subtypes (p < 0.01). BCC and SCC are common malignancies developing at various ages and anatomical sites. These data underline the need for better registration policies regarding NMSC in order to improve prevention and treatment strategies for these tumours.

Non-melanoma Skin Cancer in Canada Chapter 2: Primary Prevention of Non-melanoma Skin Cancer

2015 ◽  
Vol 19 (3) ◽  
pp. 216-226 ◽  
Author(s):  
Kirk Barber ◽  
Gordon E. Searles ◽  
Ronald Vender ◽  
Hwee Teoh ◽  
John Ashkenas
Keyword(s):  
Public Health ◽  
Primary Prevention ◽  
Skin Cancer ◽  
Skin Cancer Prevention ◽  
Accurate Information ◽  
Non Melanoma Skin Cancer ◽  
Literature Searches ◽  
Canadian Health ◽  
Canadian Health Care ◽  
Melanoma Skin

Background Non-melanoma skin cancer (NMSC), including basal and squamous cell carcinoma (BCC and SCC), represents the most common malignancy. Objective To provide guidance to Canadian health care practitioners regarding primary prevention of NMSC. Methods Structured literature searches were conducted, using search terms including prevention, sunscreen, and sun prevention factor. All recommendations concern guidance that physicians should regularly discuss with their patients to help establish photoprotection habits. The GRADE system was used to assign strength to each recommendation. Results Ultraviolet exposure is the major modifiable risk factor for NMSC. Aspects of photoprotection, including effective sunscreen use and avoidance of both the midday sun and artificial tanning, are discussed. Several widespread misunderstandings that undermine responsible public health measures related to sun safety are addressed. Conclusions Photoprotection represents both an individual priority and a public health imperative. By providing accurate information during routine patient visits, physicians reinforce the need for ongoing skin cancer prevention.

The incidence of non-melanoma skin cancer after a single field treatment with aminolevulinic acid and blue light photodynamic therapy

2009 ◽  
Vol 27 (15_suppl) ◽  
pp. e14646-e14646
Author(s):  
O. N. Kozyreva ◽  
N. Konnikov
Keyword(s):  
Photodynamic Therapy ◽  
High Risk ◽  
Skin Cancer ◽  
Aminolevulinic Acid ◽  
Non Melanoma Skin Cancer ◽  
Before And After ◽  
The Face ◽  
Risk Patients ◽  
History Of ◽  
Melanoma Skin

e14646 Background: Non-melanoma skin cancer (NMSC) is the most common form of human cancer. Aminolevulinic acid photodynamic therapy (ALA PDT) is a safe and effective treatment for NMSC precursors. It is unknown if ALA PDT treatment will affect incidence of NMSC in high risk patients (pts). Methods: A retrospective study was undertaken using a Veteran Affairs Boston Health Care System Medical Record Database. Study population included immunocompetent pts with history of NMSC, multiple actinic keratosis (AKs), and moderate to severe dermatoheliosis (DH). Study pts received a single application of 20 % ALA to the face or scalp following by exposure to blue light at 10 J/cm2. Differences in incidence of NMSC two years prior and two years after ALA PDT were tested using the Wilcoxon rank sum test. Data were analyzed by the median and interquartile range (IQR). Results: 43 Caucasian males (range 59- 87 yrs), 37 (87%) had history of NMSC on the face or scalp, 32 (78%) had basal cell carcinoma (BCC), 11 (22%) squamous cell carcinoma (SCC), 100% of patients had multiple (>4) AKs prior to treatment and 23 (75% ) had moderate to severe DH determined by Griffiths scale. Prior to ALA-PDT 74 NMSC's were documented: 40 (54%) BCC and 34 (46%) SCC. 46 NMSC's were documented following ALA-PDT: 22 (48%) BCC and 24 (52%) SCC. Prior to ALA-PDT, the frequency of BCC averaged 2 [IQR 1 to 3, max=4], and the frequency of SCC averaged 1 [IQR 1 to 1, max=3]. Following ALA-PDT, the occurrence of BCC averaged 1 [IQR 0 to 1, max=5], and that of SCC averaged 1 [IQR 0 to 2, max= 4]. The difference between BCC frequency before and after ALA-PDT treatment shown a significant reduction in BCC incidence (P = 0.0018). No such differences were observed between the frequency of SCC before and after ALA-PDT (P=0.6230) Conclusions: A single ALA-PDT treatment to the face or scalp in high risk patients significantly reduces the incidence of BCC, the incidence of SCC was not reduced. The potential role of ALA PDT as a NMSC chemopreventive modality warrants further investigation in larger samples with an alternative treatment protocols. No significant financial relationships to disclose.

scholarly journals 085 TLR4 as a novel molecular target for non-melanoma skin cancer prevention

2016 ◽  
Vol 136 (5) ◽  
pp. S15
Author(s):  
J. Janda ◽  
K. Blohm-Mangone ◽  
N. Burkett ◽  
J.G. Einspahr ◽  
D.S. Alberts ◽  
...  
Keyword(s):  
Skin Cancer ◽  
Cancer Prevention ◽  
Molecular Target ◽  
Skin Cancer Prevention ◽  
Non Melanoma Skin Cancer ◽  
Melanoma Skin
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