scholarly journals Biomarkers in melanoma and non‐melanoma skin cancer prevention and risk stratification

2020 ◽  
Author(s):  
Megan H. Trager ◽  
Larisa J. Geskin ◽  
Faramarz H. Samie ◽  
Liang Liu
Keyword(s):  
Skin Cancer ◽  
Risk Stratification ◽  
Cancer Prevention ◽  
Skin Cancer Prevention ◽  
Non Melanoma Skin Cancer ◽  
Melanoma Skin

scholarly journals 085 TLR4 as a novel molecular target for non-melanoma skin cancer prevention

2016 ◽  
Vol 136 (5) ◽  
pp. S15
Author(s):  
J. Janda ◽  
K. Blohm-Mangone ◽  
N. Burkett ◽  
J.G. Einspahr ◽  
D.S. Alberts ◽  
...  
Keyword(s):  
Skin Cancer ◽  
Cancer Prevention ◽  
Molecular Target ◽  
Skin Cancer Prevention ◽  
Non Melanoma Skin Cancer ◽  
Melanoma Skin

Non-melanoma Skin Cancer in Canada Chapter 2: Primary Prevention of Non-melanoma Skin Cancer

2015 ◽  
Vol 19 (3) ◽  
pp. 216-226 ◽  
Author(s):  
Kirk Barber ◽  
Gordon E. Searles ◽  
Ronald Vender ◽  
Hwee Teoh ◽  
John Ashkenas
Keyword(s):  
Public Health ◽  
Primary Prevention ◽  
Skin Cancer ◽  
Skin Cancer Prevention ◽  
Accurate Information ◽  
Non Melanoma Skin Cancer ◽  
Literature Searches ◽  
Canadian Health ◽  
Canadian Health Care ◽  
Melanoma Skin

Background Non-melanoma skin cancer (NMSC), including basal and squamous cell carcinoma (BCC and SCC), represents the most common malignancy. Objective To provide guidance to Canadian health care practitioners regarding primary prevention of NMSC. Methods Structured literature searches were conducted, using search terms including prevention, sunscreen, and sun prevention factor. All recommendations concern guidance that physicians should regularly discuss with their patients to help establish photoprotection habits. The GRADE system was used to assign strength to each recommendation. Results Ultraviolet exposure is the major modifiable risk factor for NMSC. Aspects of photoprotection, including effective sunscreen use and avoidance of both the midday sun and artificial tanning, are discussed. Several widespread misunderstandings that undermine responsible public health measures related to sun safety are addressed. Conclusions Photoprotection represents both an individual priority and a public health imperative. By providing accurate information during routine patient visits, physicians reinforce the need for ongoing skin cancer prevention.

scholarly journals The role of ultrasonography in head and neck Non-Melanoma Skin Cancer approach: an update with a review of the literature

2020 ◽  
Author(s):  
Tiberiu Tamas ◽  
Cristian Dinu ◽  
Manuela Lenghel ◽  
Grigore Băciuț ◽  
Simion Bran ◽  
...  
Keyword(s):  
Skin Cancer ◽  
New Technologies ◽  
Treatment Plan ◽  
Full Range ◽  
Excisional Biopsy ◽  
Skin Cancer Prevention ◽  
Depth Of Invasion ◽  
Non Melanoma Skin Cancer ◽  
The Face ◽  
Melanoma Skin

Non-Melanoma Skin Cancer is one of the most common cancer types and the face is the most affected region. The diagnosis of the skin cancer relies on clinical inspection, palpation, dermoscopy followed by incisional or excisional biopsy. When skin cancers are removed from the face, many factors are involved, including aesthetics. In addition, surgical planning with preoperative acknowledgement of the tumour margins is often the key to avoid incomplete excision, the need for reintervention, or in the prevention of functional and aesthetical defects in the treatment of skin tumours. In recent years, the development of new technologies in sonography, including high frequencies transducers can provide a full range of data. It can offer valuable information regarding the size of the tumour including the depth of invasion, the extent of the tumour, histology and subtypes of the lesions which are helpful for the treatment plan. It also may be efficient in detection of positive margins after surgery and it could play a role in the treatment of skin cancer, prevention of local recurrences and overall control of the disease. K

scholarly journals The Importance of Dedicated Dermatology Clinics in the Care of Organ Transplant Recipients.

2018 ◽  
Vol 76 (4) ◽  
pp. 371-372
Author(s):  
João Borges-Costa ◽  
Günther FL Hofbauer
Keyword(s):  
Skin Cancer ◽  
Organ Transplant ◽  
Field Cancerization ◽  
Skin Cancer Prevention ◽  
Solid Organ ◽  
Transplant Recipients ◽  
Organ Transplant Recipients ◽  
Exposed Skin ◽  
Non Melanoma Skin Cancer ◽  
Melanoma Skin

Organ transplant recipients have a high risk of skin cancer associated with immunosuppressive therapy and ultraviolet radiation. The incidence of non-melanoma skin cancer, in particular is up to 65-times higher than for the normal population. Field cancerization of sun- exposed skin is also a major health issue in these patients1.In Portugal there were 895 solid organ transplants in 2017, with the majority being kidney (529) and liver (259)2.   There are already several publications concerning skin cancer in Portuguese organ transplant recipients, reporting a prevalence of non-melanoma skin cancer ranging from 15% to 25% in renal transplant recipients3,4,5and 8% in one series6that included more liver transplant recipients with relatively less immunosuppression.The sunny geographical location and sun exposure habits, namely the poor knowledge and adherence to photoprotective measures, such as hats, long-sleeved clothes or sunscreen while on outdoor work or leisure activities, pose serious difficulties for skin cancer prevention in this population. In one study concerning knowledge of sun protective measures in a population of Portuguese transplant recipients7, 29% did not know that their risk of skin cancer was increased, and 25% of those who went to the beach stayed there between 11.30 and 16:00 pm. Not surprisingly, only 8% consulted a dermatologist in the first year after transplant7.Different organizations like the Skin Care in Organ Transplant Recipients - Europe (SCOPE) or the International Transplant Skin Cancer Collaborative (ITSCC) together with institutions such as the British National Institute for Health and Clinical Excellence (NICE)8,9,10, recommend initial assessment of these patients by a dermatologist and providing them with education on photoprotection and self-examination of the skin. These patients also need regular follow-up with time intervals defined by their previous history of skin cancer and the presence of field cancerization of their sun-exposed skin. In such patients with previous skin cancer and detectable field cancerization, some authors11propose three months as time interval between appointments. Dedicated or specialist dermatology clinics for organ transplantation are recommended11,12,and have also been shown to improve compliance with photoprotection13. Their introduction in the main Portuguese referral hospitals for transplantation would allow earlier dermatological care, inclusion of dermatology among the specialties that collaborate in the transplant teams and reduction of the burden of skin cancer in these patients, saving lives and costs.   

scholarly journals Expert Consensus on Sunscreen for the Primary Prevention of Skin Cancer: Results of the Skin Cancer Prevention Working Group Conference

2021 ◽  
Vol 5 (3) ◽  
pp. 190-202
Author(s):  
Justin Marson ◽  
Aaron Farberg ◽  
Alex Glazer ◽  
Graham Litchman ◽  
Ryan Svoboda ◽  
...  
Keyword(s):  
Primary Prevention ◽  
Skin Cancer ◽  
Cancer Prevention ◽  
Working Group ◽  
Skin Cancer Prevention ◽  
Efficacy And Safety ◽  
Review Of The Literature ◽  
Level Of Evidence ◽  
Consensus Statements ◽  
Melanoma Skin

Background: Melanoma and non-melanoma skin cancers (NMSC) are the overall most common type of malignancy. Despite this fact, the use of sunscreen as a primary preventative measure for skin cancer is not ubiquitous. Objective: To review the literature regarding efficacy and safety of sunscreens and to process and condense data into overarching principles to provide guidance to the general public and improve outcomes for melanoma NMSC. Methods: A systematic review of the literature pertaining to sunscreen efficacy in the primary prevention of melanoma and non-melanoma skin cancer, safety in humans and environmental impact was conducted. Following a thorough review of the literature, the Skin Cancer Prevention Working Group (SCPWG), an expert panel consisting of dermatologists with specialized training in melanoma and NMSC diagnosis and management, employed a modified Delphi technique to reach consensus over the development of statements regarding the current level of evidence for sunscreen efficacy and safety. Final statements were only adopted after achieving a supermajority vote >80%. Results: 96 articles were identified for further review and discussion. The SCPWG developed 7 consensus statements regarding the efficacy and safety of sunscreens and their role in the prevention of melanoma and NMSC. Conclusion: The proven benefits of primary skin cancer prevention outweigh the potential/hypothetical risks of sunscreen use, especially given insufficient real-world, prospective data for the discussed risks. As experts in skin health and skin cancer pathophysiology, the SCPWG believes dermatologists are uniquely qualified to lead future studies investigating sunscreen efficacy and safety and should counsel patients and the public on skin cancer primary prevention strategies.

Texting teens to promote knowledge, attitude and behavior change for skin cancer prevention

2013 ◽  
Author(s):  
Melanie D. Hingle ◽  
Aimee Snyder ◽  
Naja McKenzie ◽  
Cynthia Thomson ◽  
Robert A. Logan ◽  
...  
Keyword(s):  
Skin Cancer ◽  
Behavior Change ◽  
Cancer Prevention ◽  
Skin Cancer Prevention ◽  
And Behavior
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