scholarly journals Stitching of sensor-navigated 3D ultrasound datasets for the determination of large thyroid volumes – a phantom study

2018 ◽  
Vol 20 (4) ◽  
pp. 480 ◽  
Author(s):  
Martin Freesmeyer ◽  
Leonard Knichel ◽  
Christian Kuehnel ◽  
Thomas Winkens

Aims: Thyroid volume has to be measured in goiters prior to radioiodine treatment to calculate the needed amount of radioactivity. Modern clinical equipment for ultrasonography shows the trend to smaller probes, so that larger goiters do not fit any longer into the probe’s field of view. This study evaluated the feasibility and accuracy of stitching procedures applied to thyroid volumetric analysis performed using three-dimensional ultrasound (3D-US).Material and methods: Ad hoc thyroid phantoms of different shapes (regular, nodular, thickened isthmus) and volumes (ranging between 50 and 400 mL) were developed. In 15 such phantoms the left and right lobes were separately scanned, and the 3D-US datasets were then assembled (stitched) using predefined landmarks and dedicated software. Volumetric analysis was then assessed via a conventional ellipsoid model (em) and manual tracing (mt). The correlation of measured and reference volumes was determined using Pearson’s correlation coefficients and Bland and Altman limits of agreement.Results: The results showed a high level of agreement (with correlation coefficients ranging from 0.974 to 0.999) for all shapes and volumes tested, including the largest volume of 400 mL. The mt method, although more time consuming, proved superior to the em.Conclusions: Stitching-mediated thyroid volumetric analysis is accurate, and its clinical performance should be investigated in future studies

2019 ◽  
Vol 21 (4) ◽  
pp. 389
Author(s):  
Philipp Seifert ◽  
Thomas Winkens ◽  
Leonard Knichel ◽  
Chirstian Kühnel ◽  
Martin Freesmeyer

Aims: To investigate the feasibility and accuracy of 3D-US extended field of view volumetric analyses acquired with mechanically-swept ultrasound probes with different measurement methods for large volume thyroid phantoms.Materials and methods: Fifteen thyroid phantoms with different shapes (regular, nodular, thickened isthmus) and volumes (50-400 mL) were created. Two different mechanically-swept US probes were used for the separate scanning of the left and right lobes: convex and linear probe. After specific modifications, the 3D-US datasets were stitched together to an extended field of view using predefined landmarks. Volumetric analyses were performed by conventional ellipsoid model and manual tracing methods. The correspondence of measured and reference volumes was calculated using Pearson’s correlation coefficients and limits of agreement according to Bland and Altman.Results: The C-probe proved feasible for the acquisition and processing of the three-dimensional ultrasound extended field of view images; very high levels of agreement (correlation coefficients for volume analyses: 0.9843-0.9992) were observed for all shapes and volumes investigated. The manual tracing method showed superior results in comparison to the ellipsoid model, but was more time consuming. The linear probe was only applicable for the 50 mL phantoms due to its limited field of view.Conclusions: The investigated mechanically-swept convex probe was suitable for the three-dimensional ultrasound extended field of view stitching of large volume thyroid phantoms. Accurate volume analyses could be carried out. The mechanically-swept linear probe is limited to a maximum of 50 m


2006 ◽  
Vol 43 (2) ◽  
pp. 129-137 ◽  
Author(s):  
Emeka Nkenke ◽  
Bernhard Lehner ◽  
Manuel Kramer ◽  
Gerd Haeusler ◽  
Stefanie Benz ◽  
...  

Objective To assess measurement errors of a novel technique for the three-dimensional determination of the degree of facial symmetry in patients suffering from unilateral cleft lip and palate malformations. Design Technical report, reliability study. Setting Cleft Lip and Palate Center of the University of Erlangen-Nuremberg, Erlangen, Germany. Patients The three-dimensional facial surface data of five 10-year-old unilateral cleft lip and palate patients were subjected to the analysis. Distances, angles, surface areas, and volumes were assessed twice. Main Outcome Measures Calculations were made for method error, intraclass correlation coefficient, and repeatability of the measurements of distances, angles, surface areas, and volumes. Results The method errors were less than 1 mm for distances and less than 1.5° for angles. The intraclass correlation coefficients showed values greater than .90 for all parameters. The repeatability values were comparable for cleft and noncleft sides. Conclusion The small method errors, high intraclass correlation coefficients, and comparable repeatability values for cleft and noncleft sides reveal that the new technique is appropriate for clinical use.


2014 ◽  
Vol 2014 ◽  
pp. 1-10 ◽  
Author(s):  
Jumat Salimon ◽  
Talal A. Omar ◽  
Nadia Salih

Two different procedures for the methylation of fatty acids (FAs) andtransfatty acids (TFAs) in food fats were compared using gas chromatography (GC-FID). The base-catalyzed followed by an acid-catalyzed method (KOCH3/HCl) and the base-catalyzed followed by (trimethylsilyl)diazomethane (TMS–DM) method were used to prepare FA methyl esters (FAMEs) from lipids extracted from food products. In general, both methods were suitable for the determination ofcis/transFAs. The correlation coefficients (r) between the methods were relatively small (ranging from 0.86 to 0.99) and had a high level of agreement for the most abundant FAs. The significant differences (P=0.05) can be observed for unsaturated FAs (UFAs), specifically for TFAs. The results from the KOCH3/HCl method showed the lowest recovery values (%R) and higher variation (from 84% to 112%), especially for UFAs. The TMS-DM method had higherRvalues, less variation (from 90% to 106%), and more balance between variation and %RSD values in intraday and interday measurements (less than 4% and 6%, resp.) than the KOCH3/HCl method, except for C12:0, C14:0, and C18:0. Nevertheless, the KOCH3/HCl method required shorter time and was less expensive than the TMS-DM method which is more convenient for an accurate and thorough analysis of richcis/transUFA samples.


2021 ◽  
Vol 3 ◽  
Author(s):  
José Luis Pastrana-Brincones ◽  
Belén Troyano-Gallegos ◽  
Juan Pablo Morillo-Baro ◽  
Raimundo López de Vinuesa-Piote ◽  
Juan Antonio Vázquez-Diz ◽  
...  

Nowadays, getting advantageous offensive situations in high-level basketball is being increasingly harder, so taking advantage of any situation in the game since the team has the ball is essential to be competitive. Therefore, the goal to achieve in this study is to evaluate using a mixed method strategy the behaviors happening in the application of the technical–tactical means performed in the transition play of professional basketball in Spain. An ad hoc observation tool made of 11 criteria and 83 exhaustive and mutually exclusive categories (E/ME) has been designed and validated by means of data quality and generalizability analyses. Indexes obtained show high reliability and validity allowing the proposed actions to be recorded (correlation coefficients are above 0.95 and generalizability coefficients are above 0.90 in all cases). A total number of 128 situations corresponding to eight games of Unicaja de Málaga in the Endesa League in the 18/19 season were observed with the Hoisan software. The analysis of the relationships among behaviors was performed using the polar coordinates technique where the one-on-one initiation, outside the zone, has been used as focal behavior. The estimation of the functions representing the vectors has also been performed to model the best fit that estimates, starting from a focal category, the relationship among this focal behavior and the rest of the mating behaviors for possible future observations. The results show significant relationships between the selected focal behavior and the mating behaviors, showing indications of behaviors allowing tactical interpretation of the game and the definition of intervention programs to improve the performance of the team.


2016 ◽  
Vol 11 (3) ◽  
pp. 577-592 ◽  
Author(s):  
Pisut Nakmuenwai ◽  
◽  
Fumio Yamazaki ◽  
Wen Liu ◽  

In this study, damage caused by Typhoon Haiyan in the city of Tacloban, Philippines is extracted from COSMO-SkyMed imagery data. A multitemporal correlation map, i.e., a color composite of the backscattering coefficients obtained on different days and their correlation coefficients, is used to indicate changes. The Hyperboloid Change Index is proposed as a measure of the level of destruction. The method is demonstrated in a three-dimensional Cartesian coordinate system to elaborate the relationships among the aforementioned parameters. Compared to other candidate methods, a hyperboloid equation is found to be the most suitable for change detection, and its resulting positive value indicates that the typhoon had a high level of impact on the area. Potential damage areas are extracted using a thresholding operation, and the results are compared to two WorldView-2 satellite images to specifically assess coastal erosion and damage to buildings and offshore fish traps.


2016 ◽  
Vol 85 (4) ◽  
Author(s):  
Urška Barbič ◽  
Ivan Verdenik ◽  
Maja Marolt Mušič ◽  
Nataša Ihan Hren

Abstract: Background: The purpose of this study was to find a three - dimensional (3D) ultrasound technique for tongue volume estimation, to compare male and female groups and to find the correlation between tongue volume and body characteristics.Methods: 3D ultrasound was performed within a group of 14 men and a group of 18 women with norm-occlusion. The collected data were analysed by annexed software and the tongue volume was estimated. The repeatability as well as intra- and inter-rater agreement was determined by calculating intra-class correlation coefficient. The Student t-test was used to determine if there were significant differences in tongue volume and body characteristics between the male and the female groups. Pearson correlation coefficients were used to assess the relationship between tongue volume and body characteristics.Results: The 3D ultrasound estimation of tongue volume was highly repeatable in terms of good intraclass correlation coefficients of repeatability (ICC: 0,997) as well as intra- and inter-rater reliabilities (ICC: 0,998 and 0,993 respectively). The male group were significantly taller, heavier and with higher BMI than the female group, and had significantly larger tongue volumes (mean of 89.2 cm3 in males vs. 67.2 cm3 in females). Only the body weights and BMIs in the male group correlated with the tongue volume.Conclusion: This study did demonstrate a valid and reproducible 3D ultrasound technique for tongue volume assessment.


2002 ◽  
Vol 111 (9) ◽  
pp. 821-827 ◽  
Author(s):  
Andreas Müller ◽  
Mario Schubert ◽  
Eggert Beleites

Luminal dimension measurements are still an unsolved problem in endoscopy. The goal of our study was to develop a 3-dimensional (3-D) measuring device for endoscopic applications. For this purpose, a fiber probe projecting a ring of laser light (laser diode, 675 nm) was integrated in a position registration system. Software was developed for image analysis, distortion correction, and export of data for 3-D display. Experimental evaluation of measuring accuracy employing plastic tubes and 15 postmortem pig trachea preparations with artificial stenosis indicated a high level of method precision (Pearson's correlation coefficients, r = 0.99 for normal tracheal lumen and r = 0.97 for high-grade stenosis; p < .0001). Our clinical experience with the technique in 10 patients with tracheal stenosis revealed no side effects and encourages us to recommend this method for other endoscopic applications. The method enhances our 3-D grasp of endoscopically examined lesions.


2010 ◽  
Vol 67 (9) ◽  
pp. 761-765 ◽  
Author(s):  
Zoran Komazec ◽  
Slobodanka Lemajic-Komazec ◽  
Rajko Jovic ◽  
Congor Nadj ◽  
Ljiljana Jovancevic ◽  
...  

Background/Aim. A more recent method, the auditory steadystate response (ASSR), has become more and more important test method due to difference that was found in previous investigations between hearing thresholds determined by the ASSR and the pure-tone audiometry (PTA). The aim of this study was to evaluate the reliability of the ASSR in determining the frequency specific hearing thresholds by establishing a correlation between the thresholds determined by PTA, as well as to evaluate the reliability of ASSR in determining the hearing threshold with respect to the level of hearing loss and the configuration of the PTA findings. Methods. The prospective study included 46 subjects (92 ears) which were assigned to groups based on their level of hearing loss and audiometric configuration. All the subjects underwent determination of hearing thresholds by PTA and ASSR without insight into their previously obtained PTA results. Results. The overall sample differences between the ASSR and PTA thresholds were 4.1, 2.5, 4.4, and 4.2 dB at 0.5, 1, 2, and 4 kHz, respectively. A high level of correlation was achieved in groups with different configurations of PTA findings. The correlation coefficients between the hearing thresholds determined by ASSR and PTA were significant in subjects with all levels of hearing loss. The differences between hearing thresholds determined by ASSR and PTA were less than 10 dB in 85% of subjects (ranging from 4 dB for moderately severe hearing loss to 7.2 dB for normal hearing). Conclusion. The ASSR is an excellent complementary method for the determination of hearing thresholds at the 4 carrier frequencies, as well as determination of the level of hearing loss and the audiometric configuration.


Author(s):  
Laura Sarno ◽  
Gabriele Saccone ◽  
Marco Di Cresce ◽  
Pasquale Martinelli ◽  
Giuseppe Maria Maruotti

ABSTRACT Accurate and timely prenatal diagnosis of spina bifida (SB) is a major challenge of actual antenatal care. The diagnosis of spina bifida may be only suspected during I trimester because the detection rate of intracranial traslucency is 50%; the final diagnosis is made in the II trimester by direct visualization of defect of spine or the presence of myelomeningocele or the visualization of indirect signs. When a spine defect is detected it is necessary a neurosurgical counseling with the patient .The degree of handicap and the survival rate depend on the level of injury, the size of the defect, and the presence of associated anomalies. In tertiary fetal medicine centers, two-dimensional (2D) and three-dimensional (3D) ultrasound allows an accurate determination of the location, type, extention of the defect. Maternal—fetal surgery for myelomeningocele repair must be offered to carefully selected patients even if there are significant maternal implications and complications How to cite this article Sarno L, Saccone G, Di Cresce M, Martinelli P, Maruotti GM. Spina Bifida—Ultrasonographic Diagnosis in First and Second Trimesters. Donald School J Ultrasound Obstet Gynecol 2017;11(4):341-346.


2020 ◽  
Vol 0 (0) ◽  
Author(s):  
Aslim Cinar ◽  
Mekin Sezik ◽  
Serenat Eris Yalcin ◽  
And Yavuz

AbstractObjectivesA small or a large cavum septi pellucidi (CSP) during routine second trimester sonography may suggest abnormal cerebral development. Therefore, determination of CSP volume with three-dimensional (3D) ultrasound can be valuable. For this purpose, we sought to evaluate the reference ranges and measurement reliability of CSP volume by Virtual Organ Computer-aided AnaLysis (VOCAL).MethodsVOCAL software was used to calculate the CSP volume from transabdominal multiplanar datasets of 99 structurally normal fetal ultrasound examinations between 19 and 24 weeks of gestation. Linear regression was utilized to determine reference intervals for CSP volumes as a function of gestational week (GW). Agreement among three evaluators with different proficiency levels (obstetrics and gynecology resident, perinatology fellow, and perinatologist) was assessed, using intraclass correlation coefficients (ICC) and 95% confidence intervals (CI).ResultsCSP volume and gestational age was positively correlated (r2=0.383, p=0.0001), represented by the following equation: 0.058–(1.016 x GW). Interobserver agreement between perinatologist and fellow was relatively high (ICC, 0.78; 95% CI, 0.70–0.85), whereas limited ultrasound experience (resident) was associated with fair agreement with non-novice observers (ICC for resident and perinatologist, 0.50; 95% CI, 0.29–0.65 and ICC for resident and fellow, 0.57; 95% CI, 0.38–0.71).ConclusionsReference ranges of CSP volumes using VOCAL from 19 0/6 through 24 6/7 weeks of gestation were established. A first-degree model to estimate CSP volume as a function of gestational age was also constructed. CSP volumetry seems reliable when evaluated by an examiner with particular 3D sonography experience.


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