scholarly journals Ultrasound and magnetic resonance imaging in the prenatal diagnosis of open spina bifida

2018 ◽  
Vol 20 (2) ◽  
pp. 221 ◽  
Author(s):  
Romeo Micu ◽  
Anca Lucia Chicea ◽  
Dan Georgian Bratu ◽  
Paula Nita ◽  
Georgiana Nemeti ◽  
...  

Open spina bifida, also known as spina bifida aperta is a neural tube defect involving the lack of closure of vertebral arches and associated meninges and/or spinal cord abnormalities.Ultrasound examination is the gold standard for the diagnosis of spina bifida aperta. It represents the main imaging tool used to ascertain this diagnosis early in gestation. Three-dimensional ultrasound is necessary to detect the level and the size of the defect. Magnetic resonance imaging (MRI) represents a more sensitive tool, giving specific information of the defect and associated anomalies, playing an important role in ruling out differential diagnosis. Due to the advent of MRI use, it is possible today to achieve in utero treatment of fetuses with this pathology. The aim of the current review is to provide an update of literature regarding the role of ultrasound and MRI in the prenatal diagnosis of spina bifida aperta.

2003 ◽  
Vol 22 (12) ◽  
pp. 1363-1368 ◽  
Author(s):  
Franca A. Gerards ◽  
Melanie A. J. Engels ◽  
Frederik Barkhof ◽  
Frank A. M. van den Dungen ◽  
R. Jeroen Vermeulen ◽  
...  

2003 ◽  
Vol 22 (4) ◽  
pp. 419-423 ◽  
Author(s):  
Rodrigo Ruano ◽  
Jean-Pierre Aubry ◽  
Isabelle Simon ◽  
Anne-Gaelle Grebille ◽  
Pascale Sonigo ◽  
...  

2016 ◽  
Vol 18 (3) ◽  
pp. 378 ◽  
Author(s):  
Talita Micheletti Helfer ◽  
Alberto Borges Peixoto ◽  
Gabriele Tonni ◽  
Edward Araujo Júnior

Craniosynostosis is defined as the process of premature fusion of one or more of the cranial sutures.  It is a common condition that occurs in about 1 to 2,000 live births. Craniosynostosis may be classified in primary or secondary. It is also classified as nonsyndromic or syndromic. According to suture commitment, craniosynostosis may affect a single suture or multiple sutures. There is a wide range of syndromes involving craniosynostosis and the most common are Apert, Pffeifer, Crouzon, Shaethre-Chotzen and Muenke syndromes. The underlying etiology of nonsyndromic craniosynostosis is unknown. Mutations in the fibroblast growth factor (FGF) signalling pathway play a crucial role in the etiology of craniosynostosis syndromes. Prenatal ultrasound`s detection rate of craniosynostosis is low. Nowadays, different methods can be applied for prenatal diagnosis of craniosynostosis, such as two-dimensional (2D) and three-dimensional (3D) ultrasound, magnetic resonance imaging (MRI), computed tomography (CT) scan and, finally, molecular diagnosis. The presence of craniosynostosis may affect the birthing process. Fetuses with craniosynostosis also have higher rates of perinatal complications. In order to avoid the risks of untreated craniosynostosis, children are usually treated surgically soon after postnatal diagnosis.


Sign in / Sign up

Export Citation Format

Share Document