Measurement of Bond Strength of Direct Heat Tissue Fusion in Arteries

2012 ◽  
Author(s):  
James D. Cezo ◽  
Virginia L. Ferguson ◽  
Kenneth D. Taylor ◽  
Mark E. Rentschler
Keyword(s):  
Bond Strength ◽  
Peel Strength ◽  
Burst Pressure ◽  
Tissue Composition ◽  
Tissue Fusion ◽  
Vessel Lumen ◽  
Surgical Tool ◽  
Arterial Tissue ◽  
Future Evaluation ◽  
Tearing Strength

Tissue fusion is a method of joining tissue using heat and pressure. Several surgical tool companies have developed devices which perform tissue fusion on blood vessels in order to perform ligation of the vessel [1]. The success or failure of these devices is contingent upon the strength of the bond it creates between opposing sides of the blood vessel lumen, yet little characterization has been done to measure the strength of this interface. Previous studies have examined the strength of tissue fusion using clinically relevant metrics such as burst pressure or tearing strength, but none have explored metrics more appropriate for determining the mechanics of the actual bond, such as peel strength or shear strength [2–3]. These clinical metrics are susceptible to large variations due to tissue composition and geometry. The goal of this study is to measure the bond’s modulus and strength using standard engineering methods. The motivation of the present work is to develop a method for quantitatively measuring the strength of the bond made during tissue fusion. This method can then be applied to quantify the strength of the fusion interface between arterial tissue using other devices and aid in future evaluation and development of tissue fusion devices to maximize the bond strength.

Evaluating temperature and duration in arterial tissue fusion to maximize bond strength

2014 ◽  
Vol 30 ◽  
pp. 41-49 ◽  
Author(s):  
James D. Cezo ◽  
Anna C. Passernig ◽  
Virginia L. Ferguson ◽  
Kenneth D. Taylor ◽  
Mark E. Rentschler
Keyword(s):  
Bond Strength ◽  
Tissue Fusion ◽  
Arterial Tissue

Bond Strength of Thermally Fused Vascular Tissue Varies With Apposition Force

2015 ◽  
Vol 137 (12) ◽  
Author(s):  
Nicholas S. Anderson ◽  
Eric A. Kramer ◽  
James D. Cezo ◽  
Virginia L. Ferguson ◽  
Mark E. Rentschler
Keyword(s):  
Bond Strength ◽  
Blood Vessels ◽  
Thermal Energy ◽  
Molecular Mechanisms ◽  
Vascular Tissue ◽  
Tissue Temperature ◽  
Tissue Fusion ◽  
Tunica Media ◽  
Adhesive Mechanics ◽  
Bond Strengths

Surgical tissue fusion devices ligate blood vessels using thermal energy and coaptation pressure, while the molecular mechanisms underlying tissue fusion remain unclear. This study characterizes the influence of apposition force during fusion on bond strength, tissue temperature, and seal morphology. Porcine splenic arteries were thermally fused at varying apposition forces (10–500 N). Maximum bond strengths were attained at 40 N of apposition force. Bonds formed between 10 and 50 N contained laminated medial layers; those formed above 50 N contained only adventitia. These findings suggest that commercial fusion devices operate at greater than optimal apposition forces, and that constituents of the tunica media may alter the adhesive mechanics of the fusion mechanism.

Affection of Manufacture Parameters and Mixture Material on Plastic Alloy Bearings

2012 ◽  
Vol 164 ◽  
pp. 37-41
Author(s):  
Cheng Yun Yang ◽  
Jin Min Peng
Keyword(s):  
Mechanical Properties ◽  
Tensile Strength ◽  
Process Parameters ◽  
Peel Strength ◽  
Manufacture Process ◽  
Orthogonal Experiments ◽  
And Performance ◽  
Orthogonal Tests ◽  
Tearing Strength ◽  
Optimal Formula

Manufacture process parameters will be obtained from experiments in research. Molding technology determines the mechanical properties and performance of the product. The influence of molding temperature and time are significant on the performance of water lubricated bearing, the plastic alloy is based on latex material, synthesized with different fillings, accelerators and other matters, and displays great mechanical and friction properties. The main performance included peel strength, tensile strength and wearing capacity. Optimization of manufacture process parameters and the orthogonal experiments on them were carried out by integrating the results of experiments and finally the optimal manufacture process was achieved. In the experiment, three-leveled orthogonal tests were conducted for the three systems to test the tensile strength, tearing strength, stress at definite elongation, hardness and tensile rate. The impacts of the respective systems were analyzed and the content of each component are determined to get the optimal formula.

Temperature Measurement Methods During Direct Heat Arterial Tissue Fusion

2013 ◽  
Vol 60 (9) ◽  
pp. 2552-2558 ◽  
Author(s):  
James D. Cezo ◽  
Eric Kramer ◽  
Kenneth D. Taylor ◽  
Virginia Ferguson ◽  
Mark E. Rentschler
Keyword(s):  
Temperature Measurement ◽  
Measurement Methods ◽  
Tissue Fusion ◽  
Arterial Tissue

Effect of Blending with Additives on Mechanical Properties of PVC Architectural Membrane Material

2011 ◽  
Vol 687 ◽  
pp. 617-620 ◽  
Author(s):  
Yu Gang Meng ◽  
Rui Ting Huo ◽  
Chun Zhi Qi ◽  
Ling Yu Chang
Keyword(s):  
Mechanical Properties ◽  
Tensile Strength ◽  
Mechanical Characteristics ◽  
Peel Strength ◽  
Pvc Membrane ◽  
Membrane Material ◽  
Chlorinated Polyethylene ◽  
Coated Fabric ◽  
Tearing Strength ◽  
Trimethoxy Silane

Polyvinyl chloride (PVC) architectural membrane material is a species of composite textile material. In comparison with other architectural membrane materials such as PTFE or ETFE, PVC membrane material is much cheaper, softer and easier construction feasibility. In this paper, g-methacryloxypropyl trimethoxy silane (KH-570), chlorinated polyethylene (CPE) and pellet binder (PB) were added into PVC paste, respectively. The mechanical properties (tensile strength, peel strength and tearing strength) of the coated fabric were investigated. It was found that the mechanical characteristics of PVC coated fabric were evidently affected by the addition of KH-570 in the coating paste. Both tensile strength and peel strength of PVC coated fabric were improved by the addition of KH-570. The addition of CPE into the coating paste had little effect on the mechanical properties of the coated fabric. The mechanical properties of the coated fabric were greatly improved by blending with PB, the peel strength enhanced 157% and the tensile strength increased 150N/50mm, but the tearing strength was largely reduced.

Tissue Hydration Influences Bursting Pressure of Fused Arteries

2013 ◽  
Author(s):  
James D. Cezo ◽  
Nicholas Anderson ◽  
Eric Kramer ◽  
Kenneth D. Taylor ◽  
Mark E. Rentschler ◽  
...  
Keyword(s):  
Triple Helix ◽  
Bound Water ◽  
Free Water ◽  
Tissue Temperature ◽  
Bursting Pressure ◽  
Tissue Fusion ◽  
Dipole Interactions ◽  
Ecm Proteins ◽  
Arterial Tissue ◽  
Thermally Driven

Tissue fusion is a complex thermally driven reaction which, through the application of heat and pressure, bonds the extracellular matrix (ECM) of neighboring tissues together. While the mechanism of this reaction is unknown, several theories do exist. Collagen is largely thought to be responsible for the formation of the fusion bond [1–3]. During tissue fusion, as the tissue temperature is elevated (> 100 °C) [4–5], collagen denatures and water is forcibly evaporated out of the tissue [6–11]. Collagen in arterial tissue is comprised of a tightly wound triple helix held in place by crosslinking. Upon denaturation, the crosslinks are broken and the helix unwinds [6–8]. It is theorized that under applied heat and pressure the denatured molecules tangling with adjacent molecules [1], crosslinking to neighboring molecules [2], or a combination of these two mechanisms are responsible for the formation of the tissue fusion bond [3]. Water is also present in the ECM which can be classified as free or bound. Free water is able to diffuse and move freely around the ECM. Bound water is held to ECM proteins through dipole interactions. During tissue fusion, the water is forcibly removed and these charged sites which interact with water are now able to interact with adjacent molecules. These charged sites would not exist if not for the removal of water from the ECM. The goal of this study is to elucidate the importance of water in the formation of the tissue fusion bond.

Parameter Selection for Peel Strength Optimization of Thermoplastic CF-PA6 for Humm3TM

2019 ◽  
Vol 809 ◽  
pp. 297-302
Author(s):  
Neha Yadav ◽  
Ralf Schledjewski
Keyword(s):  
Bond Strength ◽  
Process Parameters ◽  
Peel Test ◽  
Peel Strength ◽  
Process Window ◽  
Heating Source ◽  
Optimum Parameters ◽  
Selection For ◽  
Strength Characterization

For Automated Tape Placement process, degree of bond varies with variation in process parameters and material. Interlaminar bond strength characterization is one of the most important criteria in determining the quality of bond between two layers of thermoplastic tapes. Depending on the bond strength achieved using different process parameters, a process window is defined. Based on the process window an iterative procedure is adopted to find optimum parameters to realize maximum bond strength. This paper aims to investigate the interlaminar bond strength of thermoplastic CF-PA6, during Automated Tape Placement process. A fairly new heating source, a pulsed light solution, i.e. a humm3TM system, which delivers uniform, highly controllable heat to the nip point is used. Experiments were conducted for different process parameters and results obtained using wedge peel test were analyzed. Results acquired help in assessing the material and the heating source in terms of capabilities and efficiency.

Effect of Tearing Strength by Variations in Amount of Adhesive in Laminated Film for Liquid Package

2013 ◽  
Vol 577-578 ◽  
pp. 597-600
Author(s):  
Yukihiko Machida ◽  
Akira Shimamoto ◽  
Hiroyuki Aoki
Keyword(s):  
Tensile Strength ◽  
Physical Properties ◽  
Peel Strength ◽  
Packaging Material ◽  
Plastic Film ◽  
Large Role ◽  
Plastic Films ◽  
On Demand ◽  
Tearing Strength

Plastic film assumes a large role as packaging material in our life. Especially, by lamination which is pasting some kind of simple substances together, plastic films are able to have many kind of function on demand of usage. It is considered that enough high peel strength and tensile strength are needed for liquid package material. And it is considered that low tearing strength is needed for easy open package too. Adhesive existing at interlayer of laminated film, and the amount of adhesive may have effect on these physical properties. In this study, we changed amount of adhesive about laminated film, measured peel strength, tensile strength and tearing strength. And we investigated best suited amount of interlayer adhesive.

Substrate Pretreatments and Strength Limiting Factors in Cu-AlN Direct Bonds

1992 ◽  
Vol 282 ◽  
Author(s):  
Wan-Lan Chiang ◽  
Victor A. Greenhut ◽  
Daniel J. Shanefield ◽  
Lois A. Johnson
Keyword(s):  
Bond Strength ◽  
Failure Modes ◽  
Peel Strength ◽  
Limiting Factors ◽  
Thermal Expansion Mismatch ◽  
High Temperature Annealing ◽  
Optimum Thickness ◽  
Different Temperatures ◽  
Bond Strengths ◽  
Main Factor

ABSTRACTCu-AlN direct bonds were made by the gas-metal eutectic method. Two kinds of AlN substrates from different suppliers were used for the research. The AlN surfaces were preoxidized in O2 at three different temperatures. An optional “anneal” in Ar was applied following the oxidation procedure. Two processes were used for the bonding.The bond strengths and the failure modes were found to depend on the substrate used, the pretreatment of the AlN and bonding conditions. There was an optimum thickness for the Al2O3 layer on the AlN surface. High temperature annealing in Ar was demonstrated to effectively promote bond strength. The highest peel strength measured was 50 N/cm.A thermal expansion mismatch between Al2O3 and AlN was considered to be the main factor which dominated the ultimate bond strength. This mismatch resulted in a residual stress in the Al2O3 layer. A measurement by XRD indicated a 300 MPa tensile stress existed in the surface Al2O3 after AlN oxidation. This made Al2O3/AlN the weakest interface and limited the bond strength rather than the eutectic bond.

Studies on Chick Embryo Thrombocytes

1963 ◽  
Vol 09 (02) ◽  
pp. 291-299 ◽  
Author(s):  
Helge Stalsberg ◽  
Hans Prydz
Keyword(s):  
Chick Embryo ◽  
Bleeding Time ◽  
In Vivo Microscopy ◽  
Cut Edge ◽  
Vessel Lumen ◽  
Cellular Constituent

SummaryThe formation of hemostatic plugs were studied in the chick embryo through in vivo microscopy, in sections of hemostatic plugs and by measurements of primary bleeding time. Thrombocytes were found to be their only cellular constituent. Ability to form adequate hemostatic plugs appeared rather abruptly in embryos of stages 16-17 and coincided with an increase in thrombocyte precursors (stages III and IV).The thrombocytes initially adhere to the cut edge of the vessel. The extension of the hemostatic plug into the vessel lumen is a secondary step in plug development.

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