Design, Fabrication and Thermal Characterization of a MEMS Device for Control of Nerve Cell Growth

2003 ◽  
Author(s):  
Ankur Jain ◽  
Kevin Ness ◽  
Angie McConnell ◽  
Linan Jiang ◽  
Kenneth Goodson
Keyword(s):  
Cell Growth ◽  
Nerve Cell ◽  
Membrane Surface ◽  
Thermal Response ◽  
Thermal Characterization ◽  
Effect Of Temperature ◽  
Amorphous Nature ◽  
And Control ◽  
Growth Experiments

There has been significant work on use of MEMS for biomedical applications in the past few years. This work presents a microheater device for use in experiments to study the effect of temperature on nerve cell growth. The device consists of a thin membrane with embedded heater and temperature sensors. Nerve cells could be immobilized on the membrane surface and their growth behavior could be studied by applying different heating powers, the goal being the actuation and control of cell growth using temperature. This work presents the design and fabrication of the microheater device being used in these cell growth experiments. Experimental data and finite element modeling are used to characterize the thermal response of the device. This yields a low value of the membrane thermal conductivity which indicates the amorphous nature of the thin film.

scholarly journals Isolation and Characterization of 4-tert-Butylphenol-Utilizing Sphingobium fuliginis Strains from Phragmites australis Rhizosphere Sediment

2010 ◽  
Vol 76 (20) ◽  
pp. 6733-6740 ◽  
Author(s):  
Tadashi Toyama ◽  
Naonori Momotani ◽  
Yuka Ogata ◽  
Yuji Miyamori ◽  
Daisuke Inoue ◽  
...  
Keyword(s):  
Cell Growth ◽  
Phragmites Australis ◽  
Gas Chromatography Mass Spectrometry ◽  
Side Chains ◽  
Isolation And Characterization ◽  
Alkyl Side Chains ◽  
Basal Salts ◽  
Growth Experiments ◽  
Rhizosphere Sediment

ABSTRACT We isolated three Sphingobium fuliginis strains from Phragmites australis rhizosphere sediment that were capable of utilizing 4-tert-butylphenol as a sole carbon and energy source. These strains are the first 4-tert-butylphenol-utilizing bacteria. The strain designated TIK-1 completely degraded 1.0 mM 4-tert-butylphenol in basal salts medium within 12 h, with concomitant cell growth. We identified 4-tert-butylcatechol and 3,3-dimethyl-2-butanone as internal metabolites by gas chromatography-mass spectrometry. When 3-fluorocatechol was used as an inactivator of meta-cleavage enzymes, strain TIK-1 could not degrade 4-tert-butylcatechol and 3,3-dimethyl-2-butanone was not detected. We concluded that metabolism of 4-tert-butylphenol by strain TIK-1 is initiated by hydroxylation to 4-tert-butylcatechol, followed by a meta-cleavage pathway. Growth experiments with 20 other alkylphenols showed that 4-isopropylphenol, 4-sec-butylphenol, and 4-tert-pentylphenol, which have alkyl side chains of three to five carbon atoms with α-quaternary or α-tertiary carbons, supported cell growth but that 4-n-alkylphenols, 4-tert-octylphenol, technical nonylphenol, 2-alkylphenols, and 3-alkylphenols did not. The rate of growth on 4-tert-butylphenol was much higher than that of growth on the other alkylphenols. Degradation experiments with various alkylphenols showed that strain TIK-1 cells grown on 4-tert-butylphenol could degrade 4-alkylphenols with variously sized and branched side chains (ethyl, n-propyl, isopropyl, n-butyl, sec-butyl, tert-butyl, n-pentyl, tert-pentyl, n-hexyl, n-heptyl, n-octyl, tert-octyl, n-nonyl, and branched nonyl) via a meta-cleavage pathway but not 2- or 3-alkylphenols. Along with the degradation of these alkylphenols, we detected methyl alkyl ketones that retained the structure of the original alkyl side chains. Strain TIK-1 may be useful in the bioremediation of environments polluted by 4-tert-butylphenol and various other 4-alkylphenols.

Structural and Thermal Characterization of Antimony-Phosphate Glass

2017 ◽  
Vol 268 ◽  
pp. 33-37
Author(s):  
S.Y. Moustafa ◽  
Md Rahim Sahar ◽  
Sib Krishna Ghoshal
Keyword(s):  
Thermal Characterization ◽  
Melt Quenching ◽  
Sem Images ◽  
Amorphous Nature ◽  
Quenching Method ◽  
Xrd Patterns ◽  
New Research ◽  
Antimony Phosphate ◽  
Approximate Percentage

A new ternary glass systems of composition xSb2O3-(75-x) P2O5-25MgO, where x = 30, 40, 50 mol%; has been prepared via melt-quenching method. Synthesized glasses are characterized using XRD, FESEM, EDX, and TG/DTA measurements. The influence of varying Sb2O3 concentrations on their thermal properties and crystal structure is evaluated. The XRD patterns confirmed the amorphous nature of samples. SEM images demonstrated interesting phase formation with ribbons-like texture. Three crystalline phases were observed in this glass series which are antimony phosphate, antimony orthophosphate and cervantite. EDX spectra detected the approximate percentage of the raw elemental traces. Thermal analysis of these glasses revealed their high-molecular polymer character for Sb2O3 content at 50 mol%. Three different glass transition temperatures are achieved with three different composition each, which are (276, 381, 422 °C) at x=30 mol%, (276, 381, 470 °C) at x=40 mol% and (276, 381, 443 °C) at x=50 mol%. Furthermore, the solidus and liquidus temperature are found to decrease with increasing Sb2O3. This observation may open up new research avenues for antimony based ternary glasses.

Thermal Characterization of Resveratrol

2018 ◽  
Vol 69 (6) ◽  
pp. 1346-1351 ◽  
Author(s):  
Oana Roxana Bancuta ◽  
Andrei Chilian ◽  
Iulian Bancuta ◽  
Radu Setnescu ◽  
Tanta Setnescu ◽  
...  
Keyword(s):  
Ir Spectroscopy ◽  
Statistical Methods ◽  
Thermal Characterization ◽  
Effect Of Temperature ◽  
No Conversion ◽  
Ft Ir ◽  
Time Periods ◽  
Pearson Correlations ◽  
Ft Ir Spectroscopy

In this paper was studied effect of temperature on the trans-resveratrol till to total degradation by UV-Vis spectrophotometry and FT-IR spectroscopy. Using statistical methods, it was observed that trans-resveratrol is unstable to higher temperatures than 100 �C, even in the absence of light. However, at temperatures up to 70 � C, resveratrol was found to be enough stable for time periods as short as 30 min. Pearson correlations of absorbance values at 304 nm (characteristic for trans-resveratrol) and 286 nm (characteristic for cis-resveratrol) shown that no conversion of trans-resveratrol to cis resveratrol is produced at elevated experimental temperatures.

scholarly journals Analysis of the Influence of Reducing the Duration of a Thermal Response Test in a Water-Filled Geothermal Borehole Located in Spain

Energies ◽  
2020 ◽  
Vol 13 (24) ◽  
pp. 6693
Author(s):  
Ignacio Martín Nieto ◽  
Cristina Sáez Blázquez ◽  
Arturo Farfán Martín ◽  
Diego González-Aguilera
Keyword(s):  
Thermal Response ◽  
Thermal Characterization ◽  
Geothermal System ◽  
Thermal Response Test ◽  
Geothermal Systems ◽  
Time Intervals ◽  
Response Test ◽  
High Investment ◽  
Time Reduction

Usually thermal response tests are restricted to big geothermal projects; the high investment makes them less suitable for designing domestic low-enthalpy geothermal energy systems. The work here presented aims to study the influence of time reduction in thermal response tests on their precision. Due to the importance of the correct assessment of the thermal characterization of the ground for any kind of geothermal system, time reduction in this essay could make it more affordable to be implemented in some domestic systems. A thermal response test has been implemented, and several time intervals of the test have been considered in order to obtain different results for the thermal conductivity of the ground. The mentioned results have been then compared and also the domestic geothermal systems designed from them by the use of the geothermal software GES-CAL. Results have shown that, in some cases (our testing borehole has some singular characteristics), a significant time reduction in the data acquisition process of the thermal response test does not compromise seriously the precision of the results.

scholarly journals Effect of Temperature on the Ink Transfer of sublimation Printing Process

2021 ◽  
pp. 32-35
Author(s):  
Phung Thi Mai Hong ◽  
Hoang Thi Kieu Nguyen
Keyword(s):  
Thermal Characterization ◽  
Experimental Results ◽  
Effect Of Temperature ◽  
Optimum Operating ◽  
Processing Temperature ◽  
Printing Technology ◽  
Printing Process ◽  
Single Colour ◽  
Ink Transfer

The effect of temperature on the ink transfer of sublimation printing technology was investigated. The ink transfer was conducted by the colour density of single solid inks and the ink trapping of overprinted solid inks. The experimental results indicate that the amount of ink transferred from the colour ribbon to the substrate is determined by the thermal characterization of dye materials. The densities of single colour inks as well as the ink trapping coefficients obtain the highest values at the temperature corresponding to the endothermic peaks of the dye materials. This is the optimum operating processing temperature.

Ultrastructural identification of three types of sensory setae on copepod antennae

1995 ◽  
Vol 53 ◽  
pp. 956-957
Author(s):  
T. M. Weatherby ◽  
P.H. Lenz
Keyword(s):  
Phase Locking ◽  
Membrane Surface ◽  
Reaction Times ◽  
High Sensitivity ◽  
Structural Features ◽  
Calanoid Copepods ◽  
Marine Food Webs ◽  
Dendritic Membrane ◽  
Ultrastructural Characterization

Crustaceans, as well as other arthropods, are covered with sensory setae and hairs, including mechanoand chemosensory sensillae with a ciliary origin. Calanoid copepods are small planktonic crustaceans forming a major link in marine food webs. In conjunction with behavioral and physiological studies of the antennae of calanoids, we undertook the ultrastructural characterization of sensory setae on the antennae of Pleuromamma xiphias.Distal mechanoreceptive setae exhibit exceptional behavioral and physiological performance characteristics: high sensitivity (<10 nm displacements), fast reaction times (<1 msec latency) and phase locking to high frequencies (1-2 kHz). Unusual structural features of the mechanoreceptors are likely to be related to their physiological sensitivity. These features include a large number (up to 3000) of microtubules in each sensory cell dendrite, arising from or anchored to electron dense rods associated with the ciliary basal body microtubule doublets. The microtubules are arranged in a regular array, with bridges between and within rows. These bundles of microtubules extend far into each mechanoreceptive seta and terminate in a staggered fashion along the dendritic membrane, contacting a large membrane surface area and providing a large potential site of mechanotransduction.

Random pseudo promptings applied to the thermal characterization of a wet porous material

1999 ◽  
Vol 6 (1) ◽  
pp. 101-108 ◽  
Author(s):  
E. Delacre ◽  
D. Defer ◽  
E. Antczak ◽  
B. Duthoit
Keyword(s):  
Porous Material ◽  
Thermal Characterization

Photoacoustic thermal characterization of the dehydration process of Agar-SiO2emulsions

2005 ◽  
Vol 125 ◽  
pp. 177-180
Author(s):  
T. Lopez ◽  
M. Picquart ◽  
G. Aguirre ◽  
Y. Freile ◽  
D. H. Aguilar ◽  
...  
Keyword(s):  
Thermal Characterization ◽  
Dehydration Process
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