Advances in Oxide-Oxide CMC

2000 ◽  
Vol 122 (2) ◽  
pp. 202-205 ◽  
Author(s):  
Robert A. Jurf ◽  
Steven C. Butner

Recent advances in COI’s oxide–oxide CMC materials will be presented including basic processing steps, updated material properties, and fabrication techniques. Material properties of COI’s alumino-silicate system reinforced with various oxide fabrics will be compared, along with progress in developing a 1200°C oxide matrix system for future turbine system applications. Examples of fabricated hardware, including a subscale combustion liner, will be shown. Recent test and evaluation data will be provided. [S0742-4795(00)01802-0]

Author(s):  
Robert A. Jurf ◽  
Steven C. Butner

Recent advances in COI’s oxide-oxide CMC materials will be presented including basic processing steps, updated material properties, and fabrication techniques. Material properties of COI’s alumino-silicate system reinforced with various oxide fabrics will be compared, along with progress in developing a 1200°C oxide matrix system for future turbine system applications. Examples of fabricated hardware, including a subscale combustion liner, will be shown. Recent test and evaluation data will be provided.


2014 ◽  
Author(s):  
Bryant Wysocki ◽  
Nathan McDonald ◽  
Clare Thiem ◽  
Thomas Renz ◽  
James Bohl

2019 ◽  
Vol 116 (35) ◽  
pp. 17330-17335 ◽  
Author(s):  
Lian Zhu ◽  
Tiffany M. Richardson ◽  
Ludivine Wacheul ◽  
Ming-Tzo Wei ◽  
Marina Feric ◽  
...  

The nucleolus is a prominent nuclear condensate that plays a central role in ribosome biogenesis by facilitating the transcription and processing of nascent ribosomal RNA (rRNA). A number of studies have highlighted the active viscoelastic nature of the nucleolus, whose material properties and phase behavior are a consequence of underlying molecular interactions. However, the ways in which the material properties of the nucleolus impact its function in rRNA biogenesis are not understood. Here we utilize the Cry2olig optogenetic system to modulate the viscoelastic properties of the nucleolus. We show that above a threshold concentration of Cry2olig protein, the nucleolus can be gelled into a tightly linked, low mobility meshwork. Gelled nucleoli no longer coalesce and relax into spheres but nonetheless permit continued internal molecular mobility of small proteins. These changes in nucleolar material properties manifest in specific alterations in rRNA processing steps, including a buildup of larger rRNA precursors and a depletion of smaller rRNA precursors. We propose that the flux of processed rRNA may be actively tuned by the cell through modulating nucleolar material properties, which suggests the potential of materials-based approaches for therapeutic intervention in ribosomopathies.


2019 ◽  
Vol 6 (3) ◽  
pp. 82 ◽  
Author(s):  
Alejandra Rodriguez-Contreras

Polyhydroxyalkanoates (PHAs), a family of natural biopolyesters, are widely used in many applications, especially in biomedicine. Since they are produced by a variety of microorganisms, they possess special properties that synthetic polyesters do not have. Their biocompatibility, biodegradability, and non-toxicity are the crucial properties that make these biologically produced thermoplastics and elastomers suitable for their applications as biomaterials. Bacterial or archaeal fermentation by the combination of different carbohydrates or by the addition of specific inductors allows the bioproduction of a great variety of members from the PHAs family with diverse material properties. Poly(3-hydroxybutyrate) (PHB) and its copolymers, such as poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHVB) or poly(3-hydroxybutyrate-co-4-hydroxybutyrate) (PHB4HB), are the most frequently used PHAs in the field of biomedicine. PHAs have been used in implantology as sutures and valves, in tissue engineering as bone graft substitutes, cartilage, stents for nerve repair, and cardiovascular patches. Due to their good biodegradability in the body and their breakdown products being unhazardous, they have also been remarkably applied as drug carriers for delivery systems. As lately there has been considerable and growing interest in the use of PHAs as biomaterials and their application in the field of medicine, this review provides an insight into the most recent scientific studies and advances in PHAs exploitation in biomedicine.


MRS Bulletin ◽  
2004 ◽  
Vol 29 (2) ◽  
pp. 96-99 ◽  
Author(s):  
Wilson C.K. Poon

AbstractThis article reviews recent advances in understanding amorphous glassy states in dense colloidal suspensions with or without short-range interparticle attractions. Experiments, theory, and simulation show that two kinds of glassy states are possible, dominated respectively by repulsion and attraction. Under suitable conditions, a small change in the interparticle potential can lead to a transition between these two kinds of colloidal glasses that entails sharp changes in material properties such as the shear modulus. This may provide novel routes for fine-tuning the properties of industrial pastes and slurries.


2020 ◽  
Vol 11 (19) ◽  
pp. 4855-4870 ◽  
Author(s):  
Marc Guerre ◽  
Christian Taplan ◽  
Johan M. Winne ◽  
Filip E. Du Prez

In this minireview, we survey recent advances in the development of vitrimer materials. Focus on how to chemically control their material properties is used to highlight challenges for boosting the potential of this emerging class of polymer materials.


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