scholarly journals The Relation Between the Arterial Stress and Restenosis Rate After Coronary Stenting

2010 ◽  
Vol 4 (3) ◽  
Author(s):  
Linxia Gu ◽  
Shijia Zhao ◽  
Aswini K. Muttyam ◽  
James M. Hammel

Two commercially available stents (the Palmaz–Schatz (PS) and S670 stents) with reported high and low restenosis rates, respectively, have been investigated in this paper. Finite element models simulating the stent, plaque, and artery interactions in 3 mm stenosed right coronary arteries were developed. These models were used to determine the stress field in artery walls after stent implantation. The material properties of porcine arteries were measured and implemented in the numerical models. The stress concentration induced in the artery by the PS stent was found to be more than double that of the S670 stent. It demonstrated a good correlation with the reported restenosis rate. The effects of stent structures, compliance mismatch, plaque geometry, and level of stenosis were studied. Results suggested that stent designs and tissue properties cause alterations in vascular anatomy that adversely affect arterial stress distributions within the wall, which impact vessel responses such as restenosis. Appropriate modeling of stent, plaque, and artery interactions provided insights for evaluating alterations to the arterial mechanical environment, as well as biomechanical factors leading to restenosis.

2005 ◽  
Vol 492-493 ◽  
pp. 421-428 ◽  
Author(s):  
Rafael Schouwenaars ◽  
Víctor H. Jacobo ◽  
Sara M. Cerrud ◽  
Armando Ortiz

Journal bearings are graded systems with a metal-metal composite as the functional layer. Estimation of the microscale stress distributions is used to analyse the interaction between microstructure, material properties and damage mechanisms during wear. The analysis is executed by means of simple plane-strain finite element models mimicking experimentally observed microstructures. It is found that under realistic macrosstress conditions no tensile microstresses are induced in the triboalloy and that plastic flow is inhibited by the graded structure.


Author(s):  
Luca Cristofolini ◽  
Enrico Schileo ◽  
Mateusz Juszczyk ◽  
Fulvia Taddei ◽  
Saulo Martelli ◽  
...  

Bone biomechanics have been extensively investigated in the past both with in vitro experiments and numerical models. In most cases either approach is chosen, without exploiting synergies. Both experiments and numerical models suffer from limitations relative to their accuracy and their respective fields of application. In vitro experiments can improve numerical models by: (i) preliminarily identifying the most relevant failure scenarios; (ii) improving the model identification with experimentally measured material properties; (iii) improving the model identification with accurately measured actual boundary conditions; and (iv) providing quantitative validation based on mechanical properties (strain, displacements) directly measured from physical specimens being tested in parallel with the modelling activity. Likewise, numerical models can improve in vitro experiments by: (i) identifying the most relevant loading configurations among a number of motor tasks that cannot be replicated in vitro ; (ii) identifying acceptable simplifications for the in vitro simulation; (iii) optimizing the use of transducers to minimize errors and provide measurements at the most relevant locations; and (iv) exploring a variety of different conditions (material properties, interface, etc.) that would require enormous experimental effort. By reporting an example of successful investigation of the femur, we show how a combination of numerical modelling and controlled experiments within the same research team can be designed to create a virtuous circle where models are used to improve experiments, experiments are used to improve models and their combination synergistically provides more detailed and more reliable results than can be achieved with either approach singularly.


2011 ◽  
Vol 255-260 ◽  
pp. 1597-1602
Author(s):  
Qian Zhou ◽  
Wei Ming Yan

To protect Chinese ancient building,by theoretical calculation and finite element simulation sinkage as well as strengthening method on tenon-mortise joint of a face beam in Tai-He Palace in the Forbidden City were studied.2 strengthening methods were considered,by which calculation diagrams as well as finite element models for the beam were built and static analysis were carried out.Based on analysis results,displacement as well as stress distributions of the face beam before strengthened were obtained;Based on laws of cultural relics protection,the 2 strengthening methods were discussed and the more suitable one was selected.Results show that the main cause of sinkage of the face beam tenon relates closely to over great values of bending,tension as well as shearing stress values at the tenon-mortise joint position;The method that strengthening tenon-mortise joint by additional columns under the face beam may bring adverse effects to the substructure,however the method of using steel-wood composite system to strengthen the joint is more suitable which meets the demand of cultural relics protection.


1996 ◽  
Vol 118 (4) ◽  
pp. 473-481 ◽  
Author(s):  
Michael R. Bryant ◽  
Peter J. McDonnell

Membrane inflation tests were performed on fresh, intact human corneas using a fiber optic displacement probe to measure the apical displacements. Finite element models of each test were used to identify the material properties for four different constitutive laws commonly used to model corneal refractive surgery. Finite element models of radial keratotomy using the different best-fit constitutive laws were then compared. The results suggest that the nonlinearity in the response of the cornea is material rather than geometric, and that material nonlinearity is important for modeling refractive surgery. It was also found that linear transverse isotropy is incapable of representing the anisotropy that has been experimentally measured by others, and that a hyperelastic law is not suitable for modeling the stiffening response of the cornea.


2014 ◽  
Vol 1648 ◽  
Author(s):  
Michael Culler ◽  
Keri A. Ledford ◽  
Jason H. Nadler

ABSTRACTRemora fish are capable of fast, reversible and reliable adhesion to a wide variety of both natural and artificial marine hosts through a uniquely evolved dorsal pad. This adhesion is partially attributed to suction, which requires a robust seal between the pad interior and the ambient environment. Understanding the behavior of remora adhesion based on measurable surface parameters and material properties is a critical step when creating artificial, bio-inspired devices. In this work, structural and fluid finite element models (FEM) based on a simplified “unit cell” geometry were developed to predict the behavior of the seal with respect to host/remora surface topology and tissue material properties.


2002 ◽  
Vol 124 (3) ◽  
pp. 734-744 ◽  
Author(s):  
Ihab M. Hanna ◽  
John S. Agapiou ◽  
David A. Stephenson

The HSK toolholder-spindle connection was developed to overcome shortcomings of the 7/24 steep-taper interface, especially at higher speeds. However, the HSK system was standardized quickly, without detailed evaluation based on operational experience. Several issues concerning the reliability, maintainability, and safety of the interface have been raised within the international engineering community. This study was undertaken to analytically investigate factors which influence the performance and limitations of the HSK toolholder system. Finite Element Models were created to analyze the effects of varying toolholder and spindle taper geometry, axial spindle taper length, drawbar/clamping load, spindle speed, applied bending load, and applied torsional load on HSK toolholders. Outputs considered include taper-to-taper contact pressures, taper-to-taper clearances, minimum drawbar forces, interface stiffnesses, and stresses in the toolholder. Static deflections at the end of the holder predicted by the models agreed well with measured values. The results showed that the interface stiffness and load-carrying capability are significantly affected by taper mismatch and dimensional variations, and that stresses in the toolholder near the drive slots can be quite high, leading to potential fatigue issues for smaller toolholders subjected to frequent clamping-unclamping cycles (e.g., in high volume applications). The results can be used to specify minimum toolholder material properties for critical applications, as well as drawbar design and spindle/toolholder gaging guidelines to increase system reliability and maintainability.


2022 ◽  
Vol 12 (1) ◽  
Author(s):  
Christopher J. Stubbs ◽  
Ryan Larson ◽  
Douglas D. Cook

AbstractThe maize (Zea mays) stem is a biological structure that must balance both biotic and structural load bearing duties. These competing requirements are particularly relevant in the design of new bioenergy crops. Although increased stem digestibility is typically associated with a lower structural strength and higher propensity for lodging, with the right balance between structural and biological activities it may be possible to design crops that are high-yielding and have digestible biomass. This study investigates the hypothesis that geometric factors are much more influential in determining structural strength than tissue properties. To study these influences, both physical and in silico experiments were used. First, maize stems were tested in three-point bending. Specimen-specific finite element models were created based on x-ray computed tomography scans. Models were validated by comparison with experimental data. Sensitivity analyses were used to assess the influence of structural parameters such as geometric and material properties. As hypothesized, geometry was found to have a much stronger influence on structural stability than material properties. This information reinforces the notion that deficiencies in tissue strength could be offset by manipulation of stalk morphology, thus allowing the creation of stalks which are both resilient and digestible.


2014 ◽  
Vol 2014 (4) ◽  
pp. 114-124
Author(s):  
Юрий Костенко ◽  
Yuriy Kostenko ◽  
Анатолий Чепурной ◽  
Anatoliy Chepurnoy ◽  
Александр Литвиненко ◽  
...  

The methods of direct perturbation for finite element models of thin-walled engineering constructions for sensitivity analysis of their strength, stiffness and dynamic characteristics to the change in their thickness are proposed. The approach for prediction of distribution for natural frequencies migration as result of change in their thickness are presented. The applicability of the linearized models to determine displacements, stresses and natural frequencies slightly thinned design compared to the nominal (original) are shown. The examples of test problems are given.


2000 ◽  
Author(s):  
Ihab M. Hanna ◽  
John S. Agapiou ◽  
David A. Stephenson

Abstract The HSK toolholder-spindle connection was developed to overcome shortcomings of the 7/24 steep-taper interface, especially at higher speeds. However, the HSK system was standardized quickly, without detailed evaluation based on operational experience. Several issues concerning the reliability, maintainability, and safety of the interface have been raised within the international engineering community. This study was undertaken to analytically investigate factors which influence the performance and limitations of the HSK toolholder system. Finite Element Models were created to analyze the effects of varying toolholder and spindle taper geometry, axial spindle taper length, drawbar/clamping load, spindle speed, applied bending load, and applied torsional load on HSK toolholders. Outputs considered include taper-to-taper contact pressures, taper-to-taper clearances, minimum drawbar forces, interface stiffnesses, and stresses in the toolholder. Static deflections at the end of the holder predicted by the models agreed well with measured values. The results showed that the interface stiffness and load-carrying capability are significantly affected by taper mismatch and dimensional variations, and that stresses in the toolholder near the drive slots can be quite high, leading to potential fatigue issues for smaller toolholders subjected to frequent clamping-unclamping cycles (e.g., in high volume applications). The results can be used to specify minimum toolholder material properties for critical applications, as well as drawbar design and spindle/toolholder gaging guidelines to increase system reliability and maintainability.


Designs ◽  
2019 ◽  
Vol 3 (1) ◽  
pp. 9
Author(s):  
Sujith Bobba ◽  
Shaik Abrar ◽  
Shaik Mujeebur Rehman

The present work deals with the development of a finite element methodology for obtaining the stress distributions in thick cylindrical HK40 stainless steel pipe that carries high-temperature fluids. The material properties and loading were assumed to be random variables. Thermal stresses that are generated along radial, axial, and tangential directions are generally computed using very complex analytical expressions. To circumvent such an issue, probability theory and mathematical statistics have been applied to many engineering problems, which allows determination of the safety both quantitatively and objectively based on the concepts of reliability. Monte Carlo simulation methodology is used to study the probabilistic characteristics of thermal stresses, and was implemented to estimate the probabilistic distributions of stresses against the variations arising due to material properties and load. A 2-D probabilistic finite element code was developed in MATLAB, and the deterministic solution was compared with ABAQUS solutions. The values of stresses obtained from the variation of elastic modulus were found to be low compared to the case where the load alone was varying. The probability of failure of the pipe structure was predicted against the variations in internal pressure and thermal gradient. These finite element framework developments are useful for the life estimation of piping structures in high-temperature applications and for the subsequent quantification of the uncertainties in loading and material properties.


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