The Effect of a Lathyritic Diet on the Sensitivity of Tendon to Strain Rate

1985 ◽  
Vol 107 (2) ◽  
pp. 166-174 ◽  
Author(s):  
R. C. Haut
Keyword(s):  
Strain Rate ◽  
Tensile Failure ◽  
Yield Response ◽  
Covalent Crosslinking ◽  
Age Dependent ◽  
Diet Supplement ◽  
Failure Properties ◽  
Tail Tendon ◽  
And Control ◽  
Rat Tail

While the tensile failure properties of rat-tail tendon depend on strain rate, the sensitivity to strain rate decreases with age, especially during sexual maturation. The object of this study was to determine the effect of an experimental model of chronic lathyrism on age-dependent changes in the sensitivity of developing tendon strength to strain rate. Tensile failure experiments were conducted at high and low strain rate on tendons excised from test and control animals aged 1 to 6 mo. The tensile “yield” response of tendon was significantly affected by the diet resulting in a reduced tensile strength and failure strain. While the sensitivity of tendon failure to strain rate was slightly elevated by the experimental diet, age-dependent changes compared with controls. Since the diet supplement is thought to inhibit covalent crosslinking of collagen in the developing tendon, other factors are likely responsible for decrease in the sensitivity of tendon strength to strain rate during maturation.

Age-Dependent Influence of Strain Rate on the Tensile Failure of Rat-Tail Tendon

1983 ◽  
Vol 105 (3) ◽  
pp. 296-299 ◽  
Author(s):  
R. C. Haut
Keyword(s):  
Tensile Strength ◽  
Energy Density ◽  
Connective Tissue ◽  
Strain Rate ◽  
Failure Strain ◽  
Tensile Failure ◽  
Strength Failure ◽  
Age Dependent ◽  
Tail Tendon ◽  
Rat Tail

Sensitivity of tensile strength, failure strain, and failure energy density to strain rate was studied for rat-tail tendon (RTT), a collagen-rich connective tissue. Tendons from animals aged 1–27 months were stretched at a high (720 percent/s) and low (3.6 percent/s) strain rate. Each failure parameter increased with strain rate. However, the sensitivity of tendon failure to rate of strain decreased rapidly during growth and sexual maturation of the animal. The study provides basic data on the rate-sensitive strength of collagen fibers using RTT.

scholarly journals Chromatographic Fractionation of Acetic Acid-solubilized Rat Tail Tendon Collagen

1960 ◽  
Vol 235 (4) ◽  
pp. 989-994
Author(s):  
Alexander Kessler ◽  
Hyman Rosen ◽  
Stanley M. Levenson
Keyword(s):  
Acetic Acid ◽  
Chromatographic Fractionation ◽  
Tail Tendon ◽  
Rat Tail ◽  
Tendon Collagen

Mechanical Properties of Blends of Crystallizable Polybutadienes Containing Amorphous Polybutadiene Diblock Copolymers

1994 ◽  
Vol 67 (2) ◽  
pp. 342-347
Author(s):  
Moira Marx Nir ◽  
Robert E. Cohen
Keyword(s):  
Mechanical Properties ◽  
Molecular Weight ◽  
Surface Area ◽  
Diblock Copolymer ◽  
Diblock Copolymers ◽  
Tensile Failure ◽  
Interfacial Surface ◽  
Failure Properties ◽  
Enhanced Properties

Abstract Tensile failure properties of syndiotactic 1,2 polybutadiene/trans 1,4 polybutadiene crystalline blends are improved by addition of 5–10% amorphous 1,2 polybutadiene/1,4 polybutadiene diblock copolymer. The effect of block molecular weight and microphase behavior of the diblock copolymer was investigated. Heterogeneous diblocks enhance blend properties to a greater extent than homogeneous diblocks. In blends with enhanced properties, percent coverage of interfacial surface area by diblock is on the order of 10%.

Abstract 14768: Echocardiographic Strain Outcomes of Cardiac Resynchronization Therapy in Patients With Chemotherapy Induced Cardiomyopathy

Circulation ◽  
2020 ◽  
Vol 142 (Suppl_3) ◽  
Author(s):  
Fatima M Ezzeddine ◽  
Antoine N Saliba ◽  
Vaibhav Jain ◽  
Hector R Villarraga ◽  
Joerg Herrmann ◽  
...  
Keyword(s):  
Cardiac Resynchronization Therapy ◽  
Strain Rate ◽  
Left Ventricular ◽  
Cardiac Resynchronization ◽  
Control Group ◽  
Resynchronization Therapy ◽  
Control Groups ◽  
Left Ventricular Strain ◽  
The Mean ◽  
And Control

Introduction: Several chemotherapy agents, especially anthracyclines, are associated with the development of non-ischemic cardiomyopathy. When chemotherapy-induced cardiomyopathy (CHIC) is associated with left bundle branch block (QRS >150 ms) and a left ventricular ejection fraction (LVEF) of 35% or lower, cardiac resynchronization therapy (CRT) is often utilized to improve cardiac function and relieve symptoms. Hypothesis: CRT is associated with improvement in left ventricular strain in patients with CHIC. Methods: The study included 22 patients with CHIC and 44 age- and gender-matched controls with other types of NIC who underwent CRT implantation between 2004 and 2017. LVEF, left ventricular global longitudinal strain (GLS), systolic strain rate (SRS), and early diastolic strain rate (SRE) were assessed at baseline and 6-18 months after CRT. CRT response was defined as LVEF improvement by >5% after CRT. Results: CRT responders had a significant improvement in left ventricular GLS as compared to CRT non-responders in the control group, but not in the CHIC group (Table 1). The mean change in LVEF after CRT was similar between the CHIC and control groups (10 ± 10% versus 11 ± 11%, p= 0.67). The mean change in GLS after CRT was also similar between the two groups (-2.15 ± 4.32 versus -3.57 ± 4.02, p= 0.19). The proportion of patients whose LVEF increased by more than 5% was similar between the two groups (59% in the CHIC group versus 68% in the control group, p= 0.46). The mean changes in LV myocardial systolic and early diastolic strain rates were similar between the CHIC and control groups. Mean SRS decreased by 0.13 ± 0.14 in the CHIC group and by 0.34 ± 1.28 in the control group (p=0.45). Mean SRE increased by 0.06 ± 0.18 in the CHIC group and by 0.07 ± 0.22 in the control group (p=0.86). Conclusions: CRT is associated with improvement in left ventricular strain in patients with CHIC. Prospective studies are needed to further evaluate the echocardiographic strain outcomes of CRT in CHIC.

Polarization-dependent optical second-harmonic imaging of a rat-tail tendon

2002 ◽  
Vol 7 (2) ◽  
pp. 205 ◽  
Author(s):  
Patrick Stoller ◽  
Beop-Min Kim ◽  
Alexander M. Rubenchik ◽  
Karen M. Reiser ◽  
Luiz B. Da Silva
Keyword(s):  
Second Harmonic ◽  
Harmonic Imaging ◽  
Tail Tendon ◽  
Rat Tail
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