Dynamic Capacitance of Epicardial Coronary Arteries In Vivo

1985 ◽  
Vol 107 (1) ◽  
pp. 29-33 ◽  
Author(s):  
R. S. Reneman ◽  
T. Arts
Keyword(s):  
Coronary Artery ◽  
Coronary Arteries ◽  
Left Coronary Artery ◽  
Pressure Pulse ◽  
Front Velocity ◽  
Arterial System ◽  
The Right ◽  
Dynamic Capacitance

The dynamic capacitance of epicardial coronary arteries (i.d. ≥ 0.4 mm) in vivo was assessed from the volume stiffness and volume of these arteries. The volume stiffness was derived from the pressure wave front velocity as determined in dogs by measuring the delay time between the pressure pulses recorded proximal and distal to a segment of the anterior descending branch of the left coronary artery. The pressure pulse was generated elsewhere in the arterial system during diastole. The volume of the epicardial coronary arteries was calculated from the lengths and diameters as measured in araldite casts, making corrections for in-vitro/in-vivo differences in dimensions. The dynamic capacitance of the right coronary artery, and the anterior descending and circumflex branches of the left coronary artery at an arterial pressure of 13.3 kPa and a frequency between 7 and 30 Hz was found to be 0.0024 ± 0.0013, 0.0062 ± 0.0028 and 0.0079 ± 0.0035 mL/kPa (mean ± SD), respectively. The total capacitance of the epicardial coronary arteries was calculated to be (0.007 mL/kPa)/100 g, which is small as compared to the total capacitance of the coronary vasculature, including the intramyocardial compartment, which is in the order of (0.5 mL/kPa)/100g [1].

scholarly journals Normal values of coronary arteries branching height in women

2021 ◽  
Vol 27 (4) ◽  
pp. 41-46
Author(s):  
U.Ye. Pidvalna ◽  
D.M. Beshley ◽  
M.Z. Mirchuk ◽  
L.R. Mateshuk-Vatseba
Keyword(s):  
Body Mass Index ◽  
Coronary Artery ◽  
Body Mass ◽  
Coronary Arteries ◽  
Body Surface ◽  
Left Coronary Artery ◽  
Statistical Significance ◽  
Lower Edge ◽  
The Mean ◽  
The Right

Morphometric analysis of the structures of the aortic bulb and coronary arteries is necessary for the planning of cardiac surgery and endovascular interventions. The aim of the study was to determine the height of the coronary arteries branching in healthy women of Lviv city and Lviv region and to determine the relationship between the height of the location of the orifice of the coronary artery with anthropometric indicators. Fifteen computed tomography images with contrast of female thorax without heart and ascending aortic lesions (normal) were selected for the study. The height of the upper and lower edges of the coronary arteries was measured; height of Valsalva sinuses. The comparison of the mean values was performed according to the Student’s t-test. The correlation between the observed variables (age, height, body weight, body mass index, body surface area, height of the sinuses of Valsalva) was calculated using the Pearson linear correlation method (r). According to the study, the population group consisted of persons of the second period of adulthood (46.67 %) and the elderly (53.33 %). According to the body mass index, 80 % were overweight or obese I-II degree. The mean height of the coronary artery orifice in women without structural changes of the heart and ascending aorta was: 11.19±1.96 mm for the left and 11.68±1.80 mm for the right. The height of the orifice of the right and left coronary arteries were almost the same, without statistical significance (p=0.26). Analysis of the correlation between the values of the height of the orifice of the coronary artery did not show a probable dependence on height, weight, age, body mass index and body surface area. There is a direct relationship between the parameters of the height of the lower edge of the right coronary artery and the height of the upper edge of the right coronary artery (r=+0.75, p=0.001) and between the value of the lower edge of the left coronary artery and the upper edge of the left coronary artery (r=+0.63, p=0.01). Thus, the analysis of the correlation between the values of the height of the orifice of the coronary artery in women in norm and anthropometric indicators did not show a significant relationship. There was no statistical significance between the indicators of the height of the orifice of the right and left coronary arteries in women.

A CADAVERIC STUDY ON CORONARY ARTERY VARIATIONS AND ITS CLINICAL `SIGNIFICANCE

2021 ◽  
pp. 20-22
Author(s):  
Sony Jhansi Priya ◽  
Sangeetha A ◽  
M. Sai Krishna
Keyword(s):  
Coronary Artery ◽  
Coronary Arteries ◽  
Left Coronary Artery ◽  
Coronary Vessels ◽  
Average Diameter ◽  
Cadaveric Study ◽  
Aortic Sinus ◽  
Clinical Procedures ◽  
Human Cadavers ◽  
The Right

Coronary artery variations are one of the commonest variations observed during clinical procedures. Normally, there are two main coronary arteries, the right coronary artery (RCA), left coronary artery (LCA).Left coronary artery gives two important branches left circumex artery (LCX) and left anterior descending (LAD) arteries. Knowledge about the coronary vessels and its variations are essential to clinicians to prevent untoward injury of vessels during any procedures. To study the morphology and variations of coronar Aim: y arteries by dissection. Materials and Methods: The present study was a cadaveric study which was conducted on 50 hearts obtained from adult human cadavers. Coronary arteries were dissected to see the origin, course and variations. The data was entered in Microsoft excel sheet and expressed in percentage. The Right Results: coronary artery branched out from the right aortic sinus and had an average diameter of 3.5mm. The left coronary artery arouse from left aortic sinus and had an average diameter of 4mm. LMCA divided into two branches in 60 percent, three branches in 30 percent and four branches in 06 percent of the hearts and direct branches from left aortic sinuus in 4 percent hearts.Based on the origin of Posterior descending or interventricular artery, Right dominance was observed in 68 percent, left dominance in 26 percent, and equal dominance in 06 percent of the hearts. Conclusion: Knowledge about the variations of coronary vessels is a prerequisite for clinicians to perform interventions of coronary vessels.

Location of Early Atheroma in the Human Coronary Arteries

1981 ◽  
Vol 103 (3) ◽  
pp. 208-212 ◽  
Author(s):  
B. Fox ◽  
W. A. Seed
Keyword(s):  
Coronary Artery ◽  
Coronary Arteries ◽  
Right Coronary Artery ◽  
Left Coronary Artery ◽  
Coronary Artery Lesions ◽  
Circumferential Distribution ◽  
Mechanical Factors ◽  
The Right

We have correlated the location of early atheroma with vessel geometry in the major coronary arteries of subjects dying of noncardiovascular causes under 40 yr of age. We analyzed only those vessels affected minimally by very early (fatty) disease. In each of the three major branches, disease was concentrated close to the entrance and diminished with distance downstream. Circumferential distribution of disease was also not random. In the right coronary artery, lesions were concentrated on the inner wall of the major curvature. Immediately downstream of the entrances of both branches of the left coronary artery, the flow-dividing walls were spared. Further downstream in the left anterior, descending branch plaques followed a spiral distribution. We believe these patterns may be determined by local mechanical factors.

Effect of Aortic Stenosis on Coronary Flow Dynamics: Studies in an In-Vitro Pulse Duplicating System

1982 ◽  
Vol 104 (3) ◽  
pp. 221-225 ◽  
Author(s):  
H. N. Sabbah ◽  
P. D. Stein
Keyword(s):  
Coronary Artery ◽  
Aortic Valve ◽  
Left Ventricle ◽  
Coronary Flow ◽  
Left Coronary Artery ◽  
Valvular Stenosis ◽  
Catheter Tip ◽  
Retrograde Coronary Flow

The dynamics of retrograde coronary flow in aortic valvular stenosis was investigated in an in-vitro pulse duplicating system which had the capability of simulating coronary flow. The ventricular chamber of the pulse duplicator consisted of an opaque elastic sac molded from rubber in the shape of a left ventricle. The aortic test section consisted of an acrylic mold of the root of the aorta of a calf, which included the sinuses of Valsalva and the entrance region of both the left and right coronary arteries. Flow in the left coronary artery was modeled to deliver both a systolic and a diastolic component of flow. Studies were performed with normal porcine valves in the aortic and mitral positions and were repeated with a human stenotic valve in the aortic position. Pressures were measured in the aorta, left ventricle, and at the ostium of the left coronary artery with catheter-tip micromanometers. In the presence of a normal aortic valve, total coronary flow was adjusted to 120 ml/min of which 21 percent of the flow occurred during systole. The phasic pattern of coronary flow was similar to that shown in vivo. In the presence of a stenotic aortic valve, a small amount of retrograde coronary flow (<1 percent of total coronary flow) was observed; and this occurred during the initial phase of systole. Retrograde coronary flow during systole appears to have resulted from compression of the collapsible segment of the simulated coronary artery. This was caused by the elevated simulated intramural pressure.

The coronary arteries and cardiac veins

2019 ◽  
pp. 175-186
Keyword(s):  
Coronary Artery ◽  
Coronary Arteries ◽  
Right Coronary Artery ◽  
Coronary Sinus ◽  
Left Coronary Artery ◽  
Venous System ◽  
Cardiac Veins ◽  
Coronary Ostia ◽  
The Right

This chapter describes the anatomy of the coronary arteries and cardiac veins. It covers the coronary ostia and left coronary artery, the right coronary artery, the cardiac venous system, and the coronary sinus and its tributaries.

scholarly journals Morphometric analysis of the coronary arteries: a study of the external diameters

2016 ◽  
Vol 33 (03) ◽  
pp. 138-141 ◽  
Author(s):  
J. Silva ◽  
A. Nagato ◽  
R. Reis ◽  
C. Nardeli ◽  
F. Abreu ◽  
...  
Keyword(s):  
Coronary Artery ◽  
Coronary Arteries ◽  
Right Coronary Artery ◽  
Left Coronary Artery ◽  
The Body ◽  
External Diameter ◽  
Artery Disease ◽  
Student’S T ◽  
The Right ◽  
The Masses

Abstract Introduction: Approximately a third of worldwide deaths are caused by ischemic or coronary heart disease, suggesting that greater attention is needed to study the coronary diameter and myocardial vasculature. Material and Methods: In this study, 39 human adult hearts were dissected. The masses of the hearts were measured according to the principle of Scherle and the external diameters of the right coronary artery, the left coronary artery, and the ascending part of the Aorta were measured in millimeters (mm), using a Mitutoyo digital caliper. In the statistical analysis, normal distribution of the variables was assessed using the Kolmogorov-Smirnov test, external diameters were compared using the unpaired Student's t-test, and Pearson's correlation was applied to investigate the correlation of the diameters of the left coronary artery and right coronary artery with the Aorta. Significance was set at P <0.05, and the data were analyzed using GraphPad Prism v.5.00 (GraphPad Software, San Diego, CA). Results: The external diameters were as follows: left coronary artery, 5.55±0.16 mm; right coronary artery, 4.38±0.15 mm (P <0.0001); and Aorta, 22.85±0.80 mm. Thus, it was demonstrated that the external diameter of the left coronary artery is 22% larger than that of the right coronary artery, resulting in a greater blood supply via the left coronary artery and a greater passage of atherosclerotic factors. Conclusions: Despite the importance of the coronary arteries for the heart and the body as a whole, few studies correlated morphometric data and possible clinical implications related to coronary artery disease.

Unusual coronary artery arrangement in D-transposition of the great arteries with ventricular septal defect

2020 ◽  
pp. 1-3
Author(s):  
Salima Ahmed Bhimani ◽  
Rukmini Komarlu
Keyword(s):  
Coronary Artery ◽  
Ventricular Septal Defect ◽  
Coronary Arteries ◽  
Right Coronary Artery ◽  
Left Coronary Artery ◽  
Septal Defect ◽  
Systolic Function ◽  
Ductus Arteriosus ◽  
Antegrade Flow ◽  
The Right

A term female with prenatally diagnosed D-Transposition of the great arteries, large membranous ventricular septal defect with inlet extension, moderate secundum atrial septal defect, and large patent ductus arteriosus (Fig 1) was born by scheduled caesarean section. Transthoracic echocardiogram confirmed the anatomy with both coronary arteries arising from a single sinus with separate ostia. The right coronary artery arose from right posterior facing sinus (Fig 2). The left coronary artery arose anomalously from the same sinus adjacent to the right coronary artery ostium, coursing posterior to the aorta, with brief intramural and interarterial course before bifurcating into the left anterior descending and left circumflex coronary arteries (Figs 3 and 4). As a result of this unique coronary pattern, she underwent unroofing of the intramural left coronary artery noted on opening the aortic root to the coronary ostium. Both coronary buttons were harvested and this large button was then divided into two buttons. The left coronary artery button was implanted with a trapdoor technique, right coronary artery button was implanted, and the remainder of the arterial switch procedure along with LeCompte maneuver was completed uneventfully, with closure of the atrial and ventricular septal defects. The post-operative course was uneventful and the patient was discharged on the seventh post-operative day. At discharge, the patient had normal biventricular systolic function, no residual intracardiac shunt, and robust antegrade flow in the reimplanted coronary arteries. The patient was growing well at the fourth month post-operative visit with normal biventricular function, patent coronaries, and outflow tracts.

Preoperative identification of coronary arterial anatomy in complete transposition, and outcome after the arterial switch operation

2002 ◽  
Vol 12 (3) ◽  
pp. 240-247 ◽  
Author(s):  
Colin J. McMahon ◽  
Howaida G. El Said ◽  
Timothy F. Feltes ◽  
Carmen H. Watrin ◽  
Beth A. Hess ◽  
...  
Keyword(s):  
Coronary Artery ◽  
Coronary Arteries ◽  
Left Coronary Artery ◽  
Arterial Switch Operation ◽  
Circumflex Coronary Artery ◽  
Arterial Switch ◽  
Complete Transposition ◽  
Switch Operation ◽  
The Right ◽  
Arterial Anatomy

Background: Perceived correlation between the coronary arterial anatomy in patients with complete transposition, and the outcome of the arterial switch procedure, has made preoperative identification of their patterns standard practice. Purpose: Our purpose was to assess the accuracy of preoperative echocardiographic identification of coronary arterial patterns, to evaluate the necessity of preoperative imaging by angiography, and to determine the impact of the coronary arterial anatomy on outcome. Methods: We reviewed the medical records of all patients referred for an arterial switch operation between August 1995 and January 2000. The anatomy as described at the time of the operation using the Leiden convention was compared to the preoperative echocardiographic and angiographic findings. Results: The procedure had been performed in 67 patients, at a mean age of 9 days, with a range from 3 days to 15 months. In 42 patients, the ventricular septum was intact, while 21 patients had a ventricular septal defect, and the other four had double outlet right ventricle with the aorta anterior and rightward. In 52 patients, the left coronary artery arose from sinus #1, and the right from sinus #2. In 8 patients, the interventricular branch of the left coronary artery arose from sinus #1, with the circumflex coronary artery arising together with the right coronary artery from sinus #2. In three patients, all three coronary arteries arose from sinus #1, while in the remaining individual patients, a large conal branch arose with the left coronary artery from sinus #1, the right coronary and left anterior descending arteries arose from sinus #1, all three coronary arteries took origin from sinus #2, and the left anterior descending and right coronary artery arose from sinus #1 with no circumflex coronary artery identifiable, respectively. In two patients (4%), we identified an intramural coronary arterial course. Echocardiography and angiography were comparable (81% versus 86%) in delineating the coronary arterial anatomy. Patients with a single arterial orifice, or an atypical coronary arterial anatomy, had a slightly longer stay on the intensive care unit, and in the hospital, but showed no difference in mortality. In fact, there was no early mortality (70% confidence limits; 0–2.9%), while two patients died late (2.9%). Conclusion: We conclude that complex coronary arterial anatomy does not preclude a successful arterial switch procedure, although patients with a single coronary artery, or other arterial patterns, had a slightly longer hospital course. Preoperative echocardiographic evaluation is comparable to non-selective coronary angiography. Irrespective of complexity, nonetheless, the coronary arteries can successfully be translocated, obviating the need for preoperative coronary angiography.

scholarly journals Origin and distribution of the coronary arteries of boars

2019 ◽  
Vol 55 (4) ◽  
pp. e149316
Author(s):  
Tânia Ribeiro Junqueira Borges ◽  
Lucas De Assis Ribeiro ◽  
Fabiano Braz Romão ◽  
Henrique Inhauser Riceti Magalhães ◽  
Marcos Martins Luz ◽  
...  
Keyword(s):  
Coronary Artery ◽  
Coronary Arteries ◽  
Left Coronary Artery ◽  
Low Cost ◽  
Blood Perfusion ◽  
Process Models ◽  
Pharmacological Studies ◽  
The Right ◽  
Domestic Swine ◽  
Potential Use

The heart of a domestic swine is similar to that of a human regarding anatomy, blood perfusion, and distribution of nurturing arteries. In addition to the similarities, its low cost compared with other species is also one of the reasons these animals have been increasingly used in medical schools and in clinical, surgical, and pharmacological studies. Therefore, we aimed to identify the origin and distribution of the right and left coronary arteries of boars, emphasizing the configuration and macroscopic representativity of their branches while characterizing a possible dominance concerning the type of circulation and the potential use of this animal as an experimental model, hence boars are the ancestors of the domestic pigs. The left coronary artery has bifurcated into paraconal interventricular branch and circumflex branch; or it has trifurcated into paraconal interventricular branch, the oblique branch, and into the left circumflex branch. The right coronary artery has originated the marginal branches to the right ventricle and the right circumflex branch, which has branched out in the subsinuous interventricular branch. Anastomoses have stood out among the paraconal and subsinuous interventricular branches – where a right dominant coronary artery occurred – and between the right and left circumflex branches. We concluded that the morphology and the distribution of the coronary arteries of boars resemble those of a human and, thus, our results are useful for the conception of experimental hemodynamics and possible use as process models.

Pulsatile Flow in the Human Left Coronary Artery Bifurcation: Average Conditions

1996 ◽  
Vol 118 (1) ◽  
pp. 74-82 ◽  
Author(s):  
Xiaoyi He ◽  
David N. Ku
Keyword(s):  
Shear Stress ◽  
Coronary Artery ◽  
Wall Shear Stress ◽  
Coronary Arteries ◽  
Left Coronary Artery ◽  
Outer Wall ◽  
Oscillatory Behavior ◽  
Circumflex Artery ◽  
Wall Shear

The localization of atherosclerosis in the coronary arteries may be governed by local hemodynamic features. In this study, the pulsatile hemodynamics of the left coronary artery bifurcation was numerically simulated using the spectral element method for realistic in vivo anatomic and physiologic conditions. The velocity profiles were found to be skewed in both the left anterior descending and the circumflex coronary arteries. Velocity skewing arose from the bifurcation as well as from the curvature of the artery over the myocardial surface. Arterial wall shear stress was significantly lower in the bifurcation region, including the side walls. The greatest oscillatory behavior was localized to the outer wall of the circumflex artery. The time-averaged mean wall shear stress varied from about 3 to 98 dynes/cm2 in the left coronary artery system. The highly localized distribution of low and oscillatory shear stress along the walls strongly correlates with the focal locations of atheroma in the human left coronary artery.

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