Simulation of Fretting Wear at Orthopaedic Implant Interfaces

2005 ◽  
Vol 127 (3) ◽  
pp. 357-363 ◽  
Author(s):  
Edward Ebramzadeh ◽  
Fabrizio Billi ◽  
Sophia N. Sangiorgio ◽  
Sarah Mattes ◽  
Werner Schmoelz ◽  
...  
Keyword(s):  
Cortical Bone ◽  
Wear Debris ◽  
Fretting Wear ◽  
Orthopaedic Implant ◽  
Joint Replacements ◽  
Total Joint Replacements ◽  
Wear Simulator ◽  
Plasma Sprayed ◽  
Fiber Mesh

Osteolysis due to wear debris is a primary cause of failure of total joint replacements. Although debris produced by the joint articulating surfaces has been studied and simulated extensively, fretting wear debris, produced at nonarticulating surfaces, has not received adequate attention. We developed a three-station fretting wear simulator to reproduce in vivo motion and stresses at the interfaces of total joint replacements. The simulator is based on the beam bending theory and is capable of producing cyclic displacement from 3to1000microns, under varying magnitudes of contact stresses. The simulator offers three potential advantages over previous studies: The ability to control the displacement by load, the ability to produce very small displacements, and dynamic normal loads as opposed to static. A pilot study was designed to test the functionality of the simulator, and verify that calculated displacements and loads produced the predicted differences between two commonly used porous ingrowth titanium alloy surfaces fretting against cortical bone. After 1.5 million cycles, the simulator functioned as designed, producing greater wear of bone against the rougher plasma-sprayed surface compared to the fiber-mesh surface, as predicted. A novel pin-on-disk apparatus for simulating fretting wear at orthopaedic implant interfaces due to micromotion is introduced. The test parameters measured with the fretting wear simulator were as predicted by design calculations, and were sufficient to measure differences in the height and weight of cortical bone pins rubbing against two porous ingrowth surfaces, plasma-sprayed titanium and titanium fiber mesh.

Load Scenarios Influence Fluid Absorption of Polyethylene

2005 ◽  
Author(s):  
T. Schwenke ◽  
C. Rieker ◽  
M. A. Wimmer
Keyword(s):  
Wear Testing ◽  
Fluid Absorption ◽  
Joint Replacements ◽  
Wear Rates ◽  
Total Joint Replacements ◽  
Fluid Uptake ◽  
Dynamically Loaded ◽  
Low Wear ◽  
Lubrication Conditions

Wear of total joint replacements is determined gravimetrically in simulator studies. A mix of bovine serum, distilled water, and additives is intended to replicate the lubrication conditions in-vivo. Weight gain due to fluid absorption during testing of UHMWPE components is corrected using a load soak station. In this study six sets of UHMWPE pins were tested for their fluid soak behavior. The samples were subjected to three different loading scenarios while being submersed in two types of commonly used lubricants. After two million cycles or 23.1 days, respectively, the different fluids lead to significantly different soaking results. Test groups that were dynamically loaded gained more weight than unloaded or statically loaded samples. The results suggest that dynamically loaded soak control stations are required during wear testing of UHMWPE components. Otherwise the fluid uptake masks the wear measurement, especially for new polyethylene materials with low wear rates. Furthermore, an agreement on detailed lubricant specifications is desirable.

Isolation, characterization and quantification of polyethylene wear debris from periprosthetic tissues around total joint replacements

Wear ◽  
2007 ◽  
Vol 262 (9-10) ◽  
pp. 1171-1181 ◽  
Author(s):  
Miroslav Slouf ◽  
Simona Eklova ◽  
Jitka Kumstatova ◽  
Stephane Berger ◽  
Hana Synkova ◽  
...  
Keyword(s):  
Wear Debris ◽  
Polyethylene Wear ◽  
Joint Replacements ◽  
Total Joint Replacements

Wear Debris in Total Joint Replacements

1994 ◽  
Vol 2 (4) ◽  
pp. 212-220 ◽  
Author(s):  
Joshua J. Jacobs ◽  
Arun Shanbhag ◽  
Tibor T. Glant ◽  
Jonathan Black ◽  
Jorge O. Galante
Keyword(s):  
Wear Debris ◽  
Joint Replacements ◽  
Total Joint Replacements

Bone-Bonding Ability of Ce-TZP/Al2O3 Nanocomposite with a Microporous Surface and Calcium Phosphate Coating

2005 ◽  
Vol 284-286 ◽  
pp. 987-990 ◽  
Author(s):  
Mitsuru Takemoto ◽  
Shunsuke Fujibayashi ◽  
J. Suzuki ◽  
Tadashi Kokubo ◽  
Takashi Nakamura
Keyword(s):  
Calcium Phosphate ◽  
Tetragonal Zirconia ◽  
Calcium Phosphate Coating ◽  
Control Group ◽  
Phosphate Coating ◽  
Joint Replacements ◽  
Total Joint Replacements ◽  
Al2o3 Composite ◽  
High Bone

The nano-composite of a ceria-stabilized tetragonal zirconia polycrystals (Ce-TZP) and alumina (Al2O3) polycrystals (Ce-TZP/Al2O3) is attractive as a load-bearing bone substitute because of its mechanical properties and phase stability. We have developed a new method of hydrofluoric acid and heat treatment (HFT) to give a microporous structure to the surface of this Ce-TZP/Al2O3 nanocomposite ceramic. Bone-bonding ability of a microporous surface and calcium phosphate coating on Ce-TZP/Al2O3 composite has been investigated through in vivo detaching model. Thin calcium phosphate coating layer was added by alternate soaking process, and thick CaP layer was produced by soaking in simulated body fluid for 5 days. HFT treated Ce-TZP/Al2O3 composite showed high bone-bonding ability compared with the control group. Thick and thin CaP coating accelerated bone-bonding ability in early post-implantation period. The submicron microporous surface was beneficial for achieving mechanical interlocking between the ceramic and surrounding bone. These results suggest the possibility of using a Ce-TZP/Al2O3 nanocomposite ceramic with microporous surface and calcium phosphate coating as the bearing material for uncemented total joint replacements.

scholarly journals An Antibiotic-Releasing Bone Void Filling (ABVF) Putty for the Treatment of Osteomyelitis

Materials ◽  
2020 ◽  
Vol 13 (22) ◽  
pp. 5080
Author(s):  
Raquib Hasan ◽  
Abbey Wohlers ◽  
Jacob Shreffler ◽  
Pranothi Mulinti ◽  
Hunter Ostlie ◽  
...  
Keyword(s):  
Bone Growth ◽  
Release Kinetics ◽  
Control Group ◽  
Joint Replacements ◽  
Total Joint Replacements ◽  
Press Fitting ◽  
Antibiotic Release ◽  
Bone Void

The number of total joint replacements (TJR) is on the rise with a corresponding increase in the number of infected TJR, which necessitates revision surgeries. Current treatments with either non-biodegradable, antibiotic-releasing polymethylmethacrylate (PMMA) based bone cement, or systemic antibiotic after surgical debridement do not provide effective treatment due to fluctuating antibiotic levels at the site of infection. Here, we report a biodegradable, easy-to-use “press-fitting” antibiotic-releasing bone void filling (ABVF) putty that not only provides efficient antibiotic release kinetics at the site of infection but also allows efficient osseointegration. The ABVF formulation was prepared using poly (D,L-lactide-co-glycolide) (PLGA), polyethylene glycol (PEG), and polycaprolactone (PCL) as the polymer matrix, antibiotic vancomycin, and osseointegrating synthetic bone PRO OSTEON for bone-growth support. ABVF was homogenous, had a porous structure, was moldable, and showed putty-like mechanical properties. The ABVF putty released vancomycin for 6 weeks at therapeutic level. Furthermore, the released vancomycin showed in vitro antibacterial activity against Staphylococcus aureus for 6 weeks. Vancomycin was not toxic to osteoblasts. Finally, ABVF was biodegradable in vivo and showed an effective infection control with the treatment group showing significantly higher bone growth (p < 0.001) compared to the control group. The potential of infection treatment and osseointegration makes the ABVF putty a promising treatment option for osteomyelitis after TJR.

Macro- and Microscale Analysis of Bearing Surface Damage on Total Shoulder Replacements

2013 ◽  
Author(s):  
Farzana Ansari ◽  
Jeff Koller ◽  
Amelia Swan ◽  
Sunny Kung ◽  
Stephen B. Gunther ◽  
...  
Keyword(s):  
Surface Damage ◽  
Bearing Surface ◽  
Joint Replacements ◽  
Total Joint Replacements ◽  
Total Knee Replacements ◽  
Uhmwpe Wear ◽  
Hip Replacements ◽  
Clinical Consequences ◽  
Bearing Damage

Damage to bearing surfaces of total joint replacements (TJR) can have clinical consequences: wear debris generated from ultra-high molecular weight polyethylene (UHMWPE) surfaces can cause osteolysis and subsequent implant loosening [1]. Counterbearing metallic damage may significantly increase UHMWPE wear [2]. Documenting the morphology, frequency and location of bearing surface damage may provide insight into wear initiation and prevention. While scoring methodologies have been available and validated for total hip replacements (THR) and total knee replacements (TKR) [3–4], there is a paucity of validated scoring protocols for total shoulder replacements (TSR) [5]. Our previous work presented a damage scoring methodology to evaluate the severity and coverage of six damage modes on retrieved cobalt chrome (CoCr) humeral heads [6]. In this study, we adapt that protocol to include bearing surface damage on the counter-bearings (UHMWPE glenoid components). Additionally, we incorporate the results of 3D profilometry analysis of scratches in the Co-Cr humeral heads [6]. Ultimately, this macroscale and microscale analysis, combined with clinical data, for coupled TSR retrievals will provide insight on the origin, evolution and consequences of bearing damage in vivo.

Profilometry Analysis and Improvements of a Novel Damage Scoring Method for Metal Bearing Surfaces of Shoulder Replacements

2012 ◽  
Author(s):  
Farzana Ansari ◽  
Eli W. Patten ◽  
Cynthia Cruz ◽  
Erin Beitel ◽  
Amelia Swan ◽  
...  
Keyword(s):  
Surface Damage ◽  
Implant Loosening ◽  
Scoring Method ◽  
Joint Replacements ◽  
Total Joint Replacements ◽  
Uhmwpe Wear ◽  
Ultra High Molecular Weight ◽  
Cobalt Chrome

Characterizing the type and extent of in vivo damage to total joint replacements (TJR) is important for improving the success of arthroplasty outcomes, modeling damage modalities, and validating simulator studies. A method for quantifying the damage present on Cobalt Chrome (CoCr) humeral heads was developed in our lab to fulfill a much-needed gap in clinical knowledge regarding total shoulder replacements as well as metallic bearing surfaces [1,2]. A lack of inter-observer consistency with regard to severity classifications from our initial protocol [1] prompted several modifications to the method, which are tested and described here in this study. Also, since sub-micron scale ultra-high molecular weight polyethylene (UHMWPE) wear debris is linked to osteolysis and implant loosening, additional analysis with high magnification 3D optical profilometry was performed on a subset of damage modes with a long-term goal of correlating surface damage with propensity for osteolysis in TJR [3,4].

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