An investigation of seeded abnormal cell concentrations in liquid based cervical cytology samples to establish minimum detection limits for raman spectroscopy

Author(s):  
A. Abekova ◽  
◽  
A. Malkin ◽  
F. Lyng
1996 ◽  
Vol 27 ◽  
pp. S293-S294 ◽  
Author(s):  
R. Vehring ◽  
B. Xu ◽  
G. Schweiger

1980 ◽  
Vol 34 (2) ◽  
pp. 144-146 ◽  
Author(s):  
Jeanne P. Haushalter ◽  
G. Patrick Ritz ◽  
David J. Wallan ◽  
Kathy Dien ◽  
Michael D. Morris

ac-coupled inverse Raman spectroscopy is shown to yield detection limits comparable to those obtained by spontaneous Raman spectroscopy. For an aqueous nitrate ion, inverse Raman limits are about 2.5 times higher than those reported for conventional measurements with similar laser powers and measurement times. Proposed improvements in instrumentation may lower detection limits another 10 times with no change in laser powers or measurement times.


1998 ◽  
Vol 64 (12) ◽  
pp. 5023-5026 ◽  
Author(s):  
A. C. Layton ◽  
M. Muccini ◽  
M. M. Ghosh ◽  
G. S. Sayler

ABSTRACT A bioluminescent reporter strain, Ralstonia eutrophaENV307(pUTK60), was constructed for the detection of polychlorinated biphenyls by inserting the biphenyl promoter upstream of the bioluminescence genes. In the presence of a nonionic surfactant, which enhances the solubility of chlorinated biphenyls, bioluminescence was induced three- to fourfold over background by biphenyl, monochlorinated biphenyls, and Aroclor 1242. The minimum detection limits for these compounds ranged from 0.15 mg/liter for 4-chlorobiphenyl to 1.5 mg/liter for Aroclor 1242.


The Analyst ◽  
2014 ◽  
Vol 139 (24) ◽  
pp. 6426-6434 ◽  
Author(s):  
Kelley C. Henderson ◽  
Edward S. Sheppard ◽  
Omar E. Rivera-Betancourt ◽  
Joo-Young Choi ◽  
Richard A. Dluhy ◽  
...  

The detection limits by NA-SERS and qPCR for the bacterial pathogenMycoplasma pneumoniaewere compared.


1992 ◽  
Vol 45 (1-4) ◽  
pp. 33-36 ◽  
Author(s):  
E.L. Sensintaffar ◽  
D.A. Chambless ◽  
D.J. Gray ◽  
S.T. Windham

1978 ◽  
Vol 32 (1) ◽  
pp. 98-100 ◽  
Author(s):  
Richard J. Thibeau ◽  
Laurent van Haverbeke ◽  
Chris W. Brown

The feasibility of resonance Raman spectroscopy in the detection of hazardous chemicals in water has been tested on some nitrophenol-based pesticides and fungicides. In most cases, detection limits below the parts per million level were obtained. The method was also tested on an artifically polluted river water sample.


1982 ◽  
Vol 26 ◽  
pp. 331-336
Author(s):  
John D. Zahrt

Recent, state of the art, x-ray spectrometers have made use of polarizing the source x-rays by scattering through 90° (1) . One then observes the analyte fluorescence in a direction perpendicular to the scattering plane in which the polarized x-rays are generated. The signal/noise ratio at the detector is much improved. Unfortunately there is a concomitant loss of intensity and analysis times increase. This adversely affects the minimum detection limits.


2000 ◽  
Vol 54 (8) ◽  
pp. 1126-1135 ◽  
Author(s):  
P. A. Mosier-Boss ◽  
S. H. Lieberman

The use of normal Raman spectroscopy and surface-enhanced Raman spectroscopy (SERS) of cationic-coated, silver substrates to detect nitrate and sulfate ions in aqueous environments is examined. For normal Raman spectroscopy using near-infrared excitation, a linear concentration response was observed with detection limits of 260 and 440 ppm for nitrate and sulfate, respectively. Detection limits in the low parts-per-million concentration range for these anions are achieved by using cationic-coated, silver SERS substrates. Adsorption of the anions on the cationic-coated SERS substrates is described by a Frumkin isotherm.


1987 ◽  
Vol 41 (3) ◽  
pp. 422-427 ◽  
Author(s):  
Liang-Tsair Lin ◽  
Charles K. Mann ◽  
Thomas J. Vickers

The feasibility of quantitative resonance Raman spectroscopy with a KrF excimer laser providing primary radiation at 249 nm has been examined. The instrumentation is described, and results are reported for measurements with a photomultiplier detector and scanning monochromator. Considerations affecting the success of the internal standardization are described. A least-squares fitting procedure is employed for quantifying the overlapped analyte and internal standard spectral lines. Instrumental detection limits of 2.2, 1.2, and 1.0 mg/L are reported for anthracene, 9-methylanthracene, and 2-methylanthracene, respectively, for spectra obtained with 120 laser pulses per step. Detection limits in the low ppb range are projected for a system employing an intensified diode array detector.


1992 ◽  
Vol 45 (1-4) ◽  
pp. 33-36
Author(s):  
E.L. Sensintaffar ◽  
D.A. Chambless ◽  
D.J. Gray ◽  
S.T. Windham

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