scholarly journals Specific hunger- and satiety-induced tuning of guinea pig enteric nerve activity

2012 ◽  
Vol 590 (17) ◽  
pp. 4321-4333 ◽  
Author(s):  
Lina Roosen ◽  
Werend Boesmans ◽  
Marjan Dondeyne ◽  
Inge Depoortere ◽  
Jan Tack ◽  
...  
Keyword(s):  
Guinea Pig ◽  
Nerve Activity ◽  
Specific Hunger

Histamine and Acetylcholine Regulation of Sympathetic Nerve Activity in Guinea-pig Nasal Mucosa

1989 ◽  
Vol 108 (sup463) ◽  
pp. 29-38 ◽  
Author(s):  
Nobuo Kubo ◽  
Hiroyuki Tsuji ◽  
Toyohiko Minami ◽  
Toshio Yamashita ◽  
Tadami Kumazawa
Keyword(s):  
Guinea Pig ◽  
Nasal Mucosa ◽  
Sympathetic Nerve ◽  
Sympathetic Nerve Activity ◽  
Nerve Activity

scholarly journals Inhibition of guinea-pig and human sensory nerve activity and the cough reflex in guinea-pigs by cannabinoid (CB2 ) receptor activation

2003 ◽  
Vol 140 (2) ◽  
pp. 261-268 ◽  
Author(s):  
Hema J Patel ◽  
Mark A Birrell ◽  
Natascia Crispino ◽  
David J Hele ◽  
Priya Venkatesan ◽  
...  
Keyword(s):  
Guinea Pig ◽  
Guinea Pigs ◽  
Sensory Nerve ◽  
Receptor Activation ◽  
Cb2 Receptor ◽  
Nerve Activity ◽  
Cough Reflex

Nociceptive nerve activity in an experimental model of knee joint osteoarthritis of the guinea pig: Effect of intra-articular hyaluronan application

Pain ◽  
2007 ◽  
Vol 130 (1) ◽  
pp. 126-136 ◽  
Author(s):  
Ana Gomis ◽  
Ana Miralles ◽  
Robert F. Schmidt ◽  
Carlos Belmonte
Keyword(s):  
Knee Joint ◽  
Guinea Pig ◽  
Experimental Model ◽  
Nerve Activity

Sa1402 Hunger- and Satiety-Cycles Tune Guinea Pig Enteric Nerve Activity

2012 ◽  
Vol 142 (5) ◽  
pp. S-294-S-295
Author(s):  
Lina Roosen ◽  
Werend Boesmans ◽  
Marjan A. Dondeyne ◽  
Inge Depoortere ◽  
Jan F. Tack ◽  
...  
Keyword(s):  
Guinea Pig ◽  
Nerve Activity

Alterations in Average Spectrum of Cochleoneural Activity by Long-Term Salicylate Treatment in the Guinea Pig: A Plausible Index of Tinnitus

1998 ◽  
Vol 80 (4) ◽  
pp. 2113-2120 ◽  
Author(s):  
Y. Cazals ◽  
K. C. Horner ◽  
Z. W. Huang
Keyword(s):  
Hearing Loss ◽  
Guinea Pig ◽  
Auditory Nerve ◽  
Acoustic Noise ◽  
Compound Action Potential ◽  
Broadband Noise ◽  
Nerve Activity ◽  
Average Spectrum ◽  
Acoustic Tuning

Cazals, Y., K. C. Horner, and Z. W. Huang. Alterations in average spectrum of cochleoneural activity by long-term salicylate treatment in the guinea pig: a plausible index of tinnitus. J. Neurophysiol. 80: 2113–2120, 1998. Salicylate, one of the most widely used drugs, produces at repetitive high doses reversible tinnitus and hearing loss. Neural correlates of hearing loss have long been established, whereas they remain elusive for tinnitus. The average spectrum of electrophysiological cochleoneural activity (ASECA), a measure of spontaneous auditory nerve activity, was monitored in guinea pigs over weeks of salicylate administration. Auditory nerve compound action potential (CAP) was also recorded to monitor acoustic sensitivity. In the first days of treatment, ASECA decreased acutely during hours after salicylate administration; after several days this decrease could be reduced. Over weeks of treatment the level of ASECA increased progressively. No change in CAP threshold was observed. The ASECA decrease induced by a contralateral broadband noise remained unchanged. At the end of treatment, acoustic tuning of ASECA showed a partially decreased sensitivity. After cessation of treatment the ASECA level returned progressively to initial values. In control animals delivery of an ipsilateral acoustic noise could reproduce the ASECA increase observed in long-term salicylate-treated animals. This white noise was of moderate sound pressure level and it elevated slightly CAP thresholds at high frequencies. These data provide evidence for salicylate-induced ASECA alterations without changes in CAP thresholds, in accord with clinical reports of tinnitus being the first subjective sign of salicylate ototoxicity. The similarities in occurrence, development, reversibility, frequency content, and acoustic level support the idea that ASECA changes, which indicates alterations of spontaneous eighth nerve activity and reflects the presence of salicylate-induced high-pitch tinnitus.

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