scholarly journals The early effects of chronic hypoxia on the cardiovascular system in the rat: role of nitric oxide

2006 ◽  
Vol 575 (1) ◽  
pp. 263-275 ◽  
Author(s):  
Martin P. Walsh ◽  
Janice M. Marshall
Keyword(s):  
Nitric Oxide ◽  
Cardiovascular System ◽  
Chronic Hypoxia ◽  
Early Effects

The Role of Nitric Oxide in the Cardiovascular System

1996 ◽  
Vol 786 (1 Near-Earth Ob) ◽  
pp. 233-244 ◽  
Author(s):  
WEE SOO SHIN ◽  
HIROYUKI KAWAGUCHI ◽  
TOSHINOBU SASAKI ◽  
YUE PENG WANG ◽  
WEI DONG YANG ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Cardiovascular System

Old and New Gasotransmitters in the Cardiovascular System: Focus on the Role of Nitric Oxide and Hydrogen Sulfide in Endothelial Cells and Cardiomyocytes

2011 ◽  
Vol 12 (9) ◽  
pp. 1406-1415 ◽  
Author(s):  
Daniele Mancardi ◽  
Alessandra Florio Pla ◽  
Francesco Moccia ◽  
Franco Tanzi ◽  
Luca Munaron
Keyword(s):  
Nitric Oxide ◽  
Endothelial Cells ◽  
Hydrogen Sulfide ◽  
Cardiovascular System ◽  
System Focus

The role of nitric oxide in regulation of the cardiovascular system in reptiles

2005 ◽  
Vol 142 (2) ◽  
pp. 205-214 ◽  
Author(s):  
Nini Skovgaard ◽  
Gina Galli ◽  
Augusto Abe ◽  
Edwin W. Taylor ◽  
Tobias Wang
Keyword(s):  
Nitric Oxide ◽  
Cardiovascular System

Molecular mechanisms underlying the role of nitric oxide in the cardiovascular system

1998 ◽  
Vol 7 (11) ◽  
pp. 1769-1779 ◽  
Author(s):  
Jean-Claude Stoclet ◽  
Eric Troncy ◽  
Bernard Muller ◽  
Claire Brua ◽  
Andrei L Kleschyov
Keyword(s):  
Nitric Oxide ◽  
Cardiovascular System ◽  
Molecular Mechanisms

scholarly journals Nitric Oxide as a Unique Bioactive Signaling Messenger in Physiology and Pathophysiology

2004 ◽  
Vol 2004 (4) ◽  
pp. 227-237 ◽  
Author(s):  
Narendra Tuteja ◽  
Mahesh Chandra ◽  
Renu Tuteja ◽  
Mithilesh K. Misra
Keyword(s):  
Nitric Oxide ◽  
Cardiovascular System ◽  
Posttranslational Modification ◽  
Penile Erection ◽  
Defense Mechanism ◽  
Target Cells ◽  
No Production ◽  
Response Modulation ◽  
Physiological Processes

Nitric oxide (NO) is an intra- and extracellular messenger that mediates diverse signaling pathways in target cells and is known to play an important role in many physiological processes including neuronal signaling, immune response, inflammatory response, modulation of ion channels, phagocytic defense mechanism, penile erection, and cardiovascular homeostasis and its decompensation in atherogenesis. Recent studies have also revealed a role for NO as signaling molecule in plant, as it activates various defense genes and acts as developmental regulator. In plants, NO can also be produced by nitrate reductase. NO can operate through posttranslational modification of proteins (nitrosylation). NO is also a causative agent in various pathophysiological abnormalities. One of the very important systems, the cardiovascular system, is affected by NO production, as this bioactive molecule is involved in the regulation of cardiovascular motor tone, modulation of myocardial contractivity, control of cell proliferation, and inhibition of platelet activation, aggregation, and adhesion. The prime source of NO in the cardiovascular system is endothelial NO synthase, which is tightly regulated with respect to activity and localization. The inhibition of chronic NO synthesis leads to neurogenic and arterial hypertensions, which later contribute to development of myocardial fibrosis. Overall, the modulation of NO synthesis is associated with hypertension. This review briefly describes the physiology of NO, its synthesis, catabolism, and targeting, the mechanism of NO action, and the pharmacological role of NO with special reference to its essential role in hypertension.

Role of nitric oxide in the cardiovascular system of South American rattlesnakes (Crotalus durissus)

2021 ◽  
Author(s):  
Samanta Aparecida Castro ◽  
Edwin T. Taylor ◽  
Driele Tavares ◽  
Renato Filogonio ◽  
Gerson Jhonatan Rodriges ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Cardiovascular System ◽  
South American ◽  
Crotalus Durissus
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