scholarly journals Kinetic and functional analysis of transient, persistent and resurgent sodium currents in rat cerebellar granule cellsin situ: an electrophysiological and modelling study

2006 ◽  
Vol 573 (1) ◽  
pp. 83-106 ◽  
Author(s):  
Jacopo Magistretti ◽  
Loretta Castelli ◽  
Lia Forti ◽  
Egidio D'Angelo
Keyword(s):  
Functional Analysis ◽  
Sodium Currents ◽  
Cerebellar Granule ◽  
Resurgent Sodium Currents ◽  
Modelling Study

scholarly journals Navβ4 Regulates Fast Resurgent Sodium Currents and Excitability in Sensory Neurons

2015 ◽  
Vol 11 ◽  
pp. s12990-015-0063 ◽  
Author(s):  
Cindy Barbosa ◽  
Zhi-Yong Tan ◽  
Ruizhong Wang ◽  
Wenrui Xie ◽  
Judith A. Strong ◽  
...  
Keyword(s):  
Sensory Neurons ◽  
Sodium Currents ◽  
Resurgent Sodium Currents

Topiramate attenuates voltage-gated sodium currents in rat cerebellar granule cells

1997 ◽  
Vol 231 (3) ◽  
pp. 123-126 ◽  
Author(s):  
Cristina Zona ◽  
Maria Teresa Ciotti ◽  
Massimo Avoli
Keyword(s):  
Granule Cells ◽  
Cerebellar Granule Cells ◽  
Sodium Currents ◽  
Cerebellar Granule ◽  
Voltage Gated

scholarly journals FHF2 isoforms differentially regulate Nav1.6-mediated resurgent sodium currents in dorsal root ganglion neurons

2016 ◽  
Vol 469 (2) ◽  
pp. 195-212 ◽  
Author(s):  
Cindy Barbosa ◽  
Yucheng Xiao ◽  
Andrew J. Johnson ◽  
Wenrui Xie ◽  
Judith A. Strong ◽  
...  
Keyword(s):  
Dorsal Root Ganglion ◽  
Dorsal Root ◽  
Dorsal Root Ganglion Neurons ◽  
Sodium Currents ◽  
Ganglion Neurons ◽  
Resurgent Sodium Currents

scholarly journals Impact Of NaV1.7-PEPD Missense Mutations That Slow The Rate Of Inactivation On Sensory Neuronal Resurgent Sodium Currents

2009 ◽  
Vol 96 (3) ◽  
pp. 663a
Author(s):  
Brian W. Jarecki ◽  
Andrew D. Piekarz ◽  
James O. Jackson ◽  
Theodore R. Cummins
Keyword(s):  
Missense Mutations ◽  
Sodium Currents ◽  
Resurgent Sodium Currents

Voltage dependent sodium currents in cultured rat cerebellar granule cells

1990 ◽  
Vol 10 (5) ◽  
pp. 445-453 ◽  
Author(s):  
Fan Lin ◽  
Oscar Moran
Keyword(s):  
Steady State ◽  
Sodium Channels ◽  
Granule Cells ◽  
Cerebellar Granule Cells ◽  
Inactivation Kinetics ◽  
Sodium Currents ◽  
Patch Clamp Technique ◽  
Cerebellar Granule ◽  
Voltage Dependent ◽  
Peak Value

Sodium currents were studied in granule cells dissociated from rat cerebellum. Macroscopic currents were recorded using the patch-clamp technique. Sudium currents, which are TTX sensitive, reached a maximum peak value of 0.42±0.08 pA/μm2 at 18.4±2.2 mV (n=6). Activation and inactivation kinetics and steady-state properties were described in terms of Hodgkin and Huxley, parameters. The properties of sodium channels in cultured rat cerebellar granule cells are very similar to those reported for various neural preparations.

scholarly journals Increased Resurgent Sodium Currents in Nav1.8 Contribute to Nociceptive Sensory Neuron Hyperexcitability Associated with Peripheral Neuropathies

2019 ◽  
Vol 39 (8) ◽  
pp. 1539-1550 ◽  
Author(s):  
Yucheng Xiao ◽  
Cindy Barbosa ◽  
Zifan Pei ◽  
Wenrui Xie ◽  
Judith A. Strong ◽  
...  
Keyword(s):  
Sensory Neuron ◽  
Peripheral Neuropathies ◽  
Sodium Currents ◽  
Resurgent Sodium Currents

Nav 1.6 channels generate resurgent sodium currents in spinal sensory neurons

FEBS Letters ◽  
2005 ◽  
Vol 579 (10) ◽  
pp. 2166-2170 ◽  
Author(s):  
Theodore R. Cummins ◽  
Sulayman D. Dib-Hajj ◽  
Raimund I. Herzog ◽  
Stephen G. Waxman
Keyword(s):  
Sensory Neurons ◽  
Sodium Currents ◽  
Resurgent Sodium Currents
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