scholarly journals Cholinergic regulation of the evoked quantal release at frog neuromuscular junction

2004 ◽  
Vol 560 (1) ◽  
pp. 77-88 ◽  
Author(s):  
Eugeny E. Nikolsky ◽  
František Vyskočil ◽  
Ella A. Bukharaeva ◽  
Dmitry Samigullin ◽  
Lev G. Magazanik
Keyword(s):  
Neuromuscular Junction ◽  
Frog Neuromuscular Junction ◽  
Quantal Release ◽  
Cholinergic Regulation

Cation dependence of posttetanic potentiation of neuromuscular transmission

1987 ◽  
Vol 252 (1) ◽  
pp. C55-C62 ◽  
Author(s):  
S. Misler ◽  
L. Falke ◽  
S. Martin
Keyword(s):  
Neuromuscular Junction ◽  
Neuromuscular Transmission ◽  
Frog Neuromuscular Junction ◽  
Posttetanic Potentiation ◽  
Quantal Content ◽  
Quantal Release ◽  
New Findings ◽  
Pump Activity ◽  
Voltage Dependent ◽  
Quantal Release Of Neurotransmitter

We have investigated the possibility that much of posttetanic potentiation (PTP) of quantal release of neurotransmitter at the frog neuromuscular junction may be due to posttetanic accumulation of [Ca2+]i, via a plasmalemmal Cao2+-Nai+ exchanger that is powered by an increase in Nai+ during the tetanus. Our new findings on the cationic dependence of PTP are consistent with this hypothesis. 1) Several manuevers that decrease Na+-K+ pump activity, (decreasing [K+]o, replacing K+o with Rb+o or Li+o, or adding acetylstrophanthidin to Ringers), all increase the intratetanic rise and prolong the posttetanic decay of epp quantal content (m) and miniature epp frequency (fmepp). 2) Increasing [Ca2+]i or [Sr2+]o, but not [Mg2+]o, increases posttetanic fmepp in a graded fashion. 3) PTP of fmepp is still present after addition of Mn2+o, which blocks voltage dependent Ca2+ entry.

scholarly journals Opposing effects of cannabinoids and vanilloids on evoked quantal release at the frog neuromuscular junction

2010 ◽  
Vol 473 (2) ◽  
pp. 97-101 ◽  
Author(s):  
Priscila Elisa Silveira ◽  
Naiara Araújo Silveira ◽  
Verônica de Cássia Morini ◽  
Christopher Kushmerick ◽  
Lígia Araujo Naves
Keyword(s):  
Neuromuscular Junction ◽  
Frog Neuromuscular Junction ◽  
Quantal Release ◽  
Opposing Effects

221 Presynaptic Ca2+-imaging at the frog neuromuscular junction

1996 ◽  
Vol 25 ◽  
pp. S36 ◽  
Author(s):  
M. Osanai ◽  
S. Suzuki ◽  
N. Suzuki ◽  
K. Kuba ◽  
H. Kijima
Keyword(s):  
Neuromuscular Junction ◽  
Frog Neuromuscular Junction
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