scholarly journals Mitochondrial Ca2+ uptake prevents desynchronization of quantal release and minimizes depletion during repetitive stimulation of mouse motor nerve terminals

2003 ◽  
Vol 548 (2) ◽  
pp. 425-438 ◽  
Author(s):  
G. David ◽  
E. F Barrett
Keyword(s):  
Motor Nerve ◽  
Repetitive Stimulation ◽  
Nerve Terminals ◽  
Motor Nerve Terminals ◽  
Quantal Release ◽  
Stimulation Of

scholarly journals Motor Nerve Terminals As the Site of Initial Functional Changes After Denervation

1969 ◽  
Vol 53 (1) ◽  
pp. 70-80 ◽  
Author(s):  
Michiko Okamoto ◽  
Walter F. Riker
Keyword(s):  
Motor Nerve ◽  
Repetitive Stimulation ◽  
Motor Nerve Terminal ◽  
Nerve Terminals ◽  
In Situ Experiment ◽  
Muscle System ◽  
Motor Nerve Terminals ◽  
Functional Changes ◽  
Post Tetanic Potentiation ◽  
Nerve Muscle

For the cat soleus nerve-muscle system, motor nerve section 48 hr prior to in situ experiment causes certain characteristic transmission losses. Responses to repetitive stimulation are sharply altered: The capacity to transmit iterative stimulation is severely reduced; post-tetanic potentiation and the post-tetanic repetition of soleus nerve terminals responsible for it are also greatly impaired; a phenomenon of post-tetanic depression was frequently observed. However, function of the extramuscular axons appears normal and single impulse transmission is usually not seriously affected. The loss of reactivity to repetitive stimulation has been traced to soleus motor nerve terminals. In view of these data and the known absence of denervation hypersensitivity at this time, the earliest functional failure may be said to occur in the unmyelinated terminals. This subacutely denervated preparation therefore offers a simple means of evaluating motor nerve terminal responsiveness.

Stimulation of Motor Nerve Terminals

Nature ◽  
1961 ◽  
Vol 191 (4793) ◽  
pp. 1103-1104 ◽  
Author(s):  
J. I. HUBBARD ◽  
ROBERT F. SCHMIDT
Keyword(s):  
Motor Nerve ◽  
Nerve Terminals ◽  
Motor Nerve Terminals ◽  
Stimulation Of

scholarly journals Targeted delivery into motor nerve terminals of inhibitors for SNARE-cleaving proteases via liposomes coupled to an atoxic botulinum neurotoxin

FEBS Journal ◽  
2012 ◽  
Vol 279 (14) ◽  
pp. 2555-2567 ◽  
Author(s):  
Om P. Edupuganti ◽  
Saak V. Ovsepian ◽  
Jiafu Wang ◽  
Tomas H. Zurawski ◽  
James J. Schmidt ◽  
...  
Keyword(s):  
Targeted Delivery ◽  
Botulinum Neurotoxin ◽  
Motor Nerve ◽  
Nerve Terminals ◽  
Motor Nerve Terminals
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